Test Price
2,800 AED✅ Home Collection Available
BMP2 Gene Brachydactyly Type A2 Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS processing for single nucleotide variants and small indels.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Post-Test Clinical Guidance: Dedicated telephonic interpretation session with a consultant medical geneticist to contextualize results.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced NGS test analyzes the entire BMP2 gene to identify pathogenic variants that cause autosomal dominant brachydactyly type A2 (BDA2), a skeletal dysplasia marked by shortened middle phalanges of the index finger and second toe. The assay provides comprehensive molecular confirmation to guide clinical management, surgical planning, and reproductive counseling.
| Feature | Our BMP2 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | Full‑gene coverage including deep intronic and regulatory regions | Limited to coding exons and splice sites; may miss non‑coding variants |
| Methodology | Next‑Generation Sequencing (Illumina‑based) with bioinformatic validation | Sanger sequencing of individual amplicons |
| Turnaround Time | 3–4 Weeks | 2 Weeks |
| Clinical Sensitivity | >99% for single nucleotide variants and small indels | ~85–90% |
Physician Insight & Safety Protocols
“Brachydactyly type A2 frequently follows an autosomal dominant inheritance pattern that can remain undetected across generations. A definitive molecular diagnosis empowers families with accurate recurrence risk assessments and informs orthopedic intervention timelines. I strongly recommend that results be reviewed in consultation with a clinical geneticist rather than interpreted in isolation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Guidance for Patients
Important Pre-Test Considerations
- Exclusion Criteria: This test should not be ordered for asymptomatic minors without parental consent and pre-test genetic counseling. It is not a substitute for emergency evaluation.
- Emergency Red Flags: If you or your child experiences acute pain, swelling, or functional loss unrelated to brachydactyly, proceed immediately to the nearest emergency department. This genetic test is designed exclusively for molecular confirmation of BDA2 and does not address urgent musculoskeletal complaints.
- Medication Continuation: Do not discontinue any prescribed medication without consulting your attending physician.
Clinical Exclusion Criteria
Circumstances Requiring Alternative Evaluation
- Patients presenting with acute trauma, infection, or inflammatory arthritis should undergo standard clinical and radiological workup prior to genetic testing.
- Individuals with a known clinical diagnosis of brachydactyly type A2 who have already received molecular confirmation through an accredited laboratory do not require repeat sequencing.
- Post-mortem genetic analysis requires specific consent and may be subject to additional legal and ethical approvals under UAE jurisdiction.
Patient FAQ & Clinical Guidance
1. What exactly does the BMP2 brachydactyly test detect?
This test analyzes the BMP2 gene for mutations causing brachydactyly type A2, a hereditary bone disorder. It identifies single nucleotide changes, small insertions/deletions, and copy number variations that lead to the classic shortening of the index fingers and second toes, confirming the clinical diagnosis and clarifying inheritance patterns.
2. How is the sample collected and what support can I expect?
A small blood sample or DNA FTA card is obtained, and our ISO-certified cold-chain home collection ensures viability. A trained phlebotomist visits you between 8 AM and 11 PM, and the sample is transported under strict temperature control to prevent degradation. You also receive pre-test genetic counseling and a post-test clinical discussion with a consultant medical geneticist.
3. How should I interpret the results and what are the next steps?
A positive result confirms a BMP2 variant and ties your clinical features directly to brachydactyly type A2. You will receive a comprehensive report detailing the specific mutation, its zygosity, and its known clinical significance. A geneticist will explain the implications for you and your family, including recurrence risk and potential orthopedic interventions.
4. Is this test covered by insurance in the UAE?
Coverage varies by insurer and policy. Our team can verify your direct billing eligibility via WhatsApp at +971 54 548 8731. We recommend contacting your insurance provider to confirm whether genetic testing for hereditary skeletal disorders is included in your plan.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework
DNA Labs UAE operates under DHA Facility License Number 1143 and strictly adheres to all applicable UAE federal laws governing health data and genetic testing:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): Governs the collection, processing, and storage of all personal health information with explicit consent requirements.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Regulates the secure handling, transfer, and confidentiality of electronic health records and genomic data.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Establishes the legal framework for clinical safety, informed patient consent, and professional accountability in diagnostic procedures.
All laboratory processes are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). Patient data is encrypted, access-restricted, and retained only as long as required by UAE health information governance standards.
Clinical & Logistical Metadata
| Test Name | BMP2 Gene Sequencing – Brachydactyly Type A2 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks (21–28 Business Days) |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or DNA FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina-based platform with bioinformatic variant validation |
| ICD-10-CM Code | Q68.1 – Congenital deformity of finger(s) and hand (Brachydactyly Type A2) |
| LOINC Code | 82316-9 – BMP2 gene mutation analysis in Blood or Tissue by Sequencing |
| DHA Facility License & Laboratory Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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