Test Price
2,800 AED✅ Home Collection Available
BCS1L Gene Mitochondrial Complex III Deficiency Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-Grade Cold-Chain Home Collection by licensed phlebotomists; VIP mobile service available 8 AM – 11 PM daily.
- Clinical Guidance: Post-test telephonic result interpretation by a DHA-licensed Clinical Geneticist to correlate with clinical phenotype.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This next-generation sequencing (NGS) test analyzes the entire coding sequence of the BCS1L gene to detect pathogenic variants causing mitochondrial complex III deficiency, a severe multi-systemic disorder often presenting as neonatal-onset encephalopathy, hepatopathy, or renal tubulopathy. The assay identifies single-nucleotide variants, small insertions/deletions, and exon-level copy number changes.
| Feature | Our Test (BCS1L NGS – ISO Lab) | Closest Alternative (Standard Single-Gene Sequencing) |
|---|---|---|
| Precision | Detection of SNVs, indels, and copy number variants with >99.9% analytical sensitivity | May miss deep intronic or regulatory mutations; lower coverage uniformity |
| Methodology | NGS (Next Generation Sequencing) on Illumina platform with full bioinformatic alignment to GRCh38 | Sanger sequencing – limited to exons, no CNV analysis |
| Turnaround Time | 12–18 Business Days from sample receipt | 6–8 Weeks |
| Price (AED) | 2,800 | ~3,500 |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I emphasize that a positive BCS1L result must be interpreted alongside neuroimaging, biochemical markers, and a three-generation pedigree. Genetic variants do not always dictate severity; supportive therapies continue to evolve. Patients and families need compassionate, multidisciplinary guidance.”
— Ms. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue or adjust any prescribed medication without explicit consultation with your treating physician. Certain drugs (e.g., valproic acid, aminoglycosides) may aggravate mitochondrial dysfunction; always inform your doctor before testing.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unstable due to acute metabolic decompensation (pH <7.2, hyperammonemia) must be stabilized before sample collection.
- Exclusion: Known interfering substances: recent heparinized sample without proper DNA extraction may inhibit sequencing. Use EDTA whole blood or FTA card.
- Red Flag Symptoms (seek immediate ER): Acute encephalopathy, seizures unresponsive to benzodiazepines, sudden loss of developmental milestones, severe lactic acidosis (lactate >5 mmol/L), or stroke-like episodes.
- Pre-test Information: A detailed clinical history and a formal genetic counselling session to draw a pedigree chart of affected family members is mandatory. This ensures appropriate variant classification and cascade testing.
Patient FAQ & Clinical Guidance
1. What does the BCS1L NGS test detect, and how long do results take?
Our comprehensive NGS test identifies pathogenic single-nucleotide variants, small deletions/insertions, and exon-level copy number changes across all coding exons of the BCS1L gene, with results delivered in 12–18 business days from sample receipt.
2. Is a home blood collection service available throughout the UAE?
Yes, we offer DHA-licensed mobile phlebotomy with ISO-certified cold-chain transport from 8 AM to 11 PM, covering all emirates, including Dubai, Abu Dhabi, Sharjah, and the Northern Emirates.
3. Will my insurance cover this genetic test, and how is my data protected?
Many UAE insurers partially or fully reimburse diagnostic mitochondrial genetic testing; we verify your coverage via WhatsApp before sample collection. All genetic data is secured under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Privacy
This service complies fully with the following UAE federal laws:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – genomic data handling and consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – health data security and storage.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – clinical testing safety and patient consent protocols.
Samples are processed in a DHA-licensed facility (License No. 1143) and ISO 9001:2015 accredited laboratory. All results are delivered under strict confidentiality protocols.
Clinical & Logistical Metadata
| Test Name | BCS1L Gene Mitochondrial Complex III Deficiency Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 12–18 Business Days |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or buccal swab; archival tissue slides accepted via secure courier |
| Methodology Used | Next-Generation Sequencing (Illumina), GRCh38 alignment, ACMG variant interpretation |
| ICD-10-CM Code | E88.49, G31.81 |
| LOINC Code | 93336-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians