Test Price
2,800 AED✅ Home Collection Available
BCS1L Gene Mitochondrial Complex III Deficiency Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل طفرات جين BCS1L المرتبط بنقص معقد الميتوكوندريا الثالث في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
Clinical Integrity & UAE-Compliant Service
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-Grade Cold-Chain Home Collection by licensed phlebotomists; VIP mobile service available 8 AM – 11 PM daily.
- Clinical Guidance: Post-test telephonic result interpretation by a DHA-licensed specialist to correlate with clinical phenotype.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
الموثوقية السريرية والامتثال الإماراتي
- ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة بتقنية التسلسل الجيني المتقدم المعتمدة من ISO 9001:2015.
- الخدمات اللوجستية المتميزة: سحب عينات منزلية بسلسلة تبريد معتمدة من قبل فنيين مرخصين، خدمة VIP متنقلة يومياً من 8 صباحاً حتى 11 مساءً.
- الاستشارة السريرية: تفسير النتيجة هاتفياً بعد الفحص من قبل أخصائي معتمد من هيئة الصحة بدبي لربطها بالصورة السريرية.
- التأمين: التحقق المباشر من تغطية التأمين عبر واتساب على الرقم +971 54 548 8731.
Test Overview
This next-generation sequencing (NGS) test analyzes the entire coding sequence of the BCS1L gene to detect pathogenic variants causing mitochondrial complex III deficiency, a severe multi-systemic disorder often presenting as neonatal-onset encephalopathy, hepatopathy, or renal tubulopathy. يكشف هذا الفحص الجيني الشامل عن طفرات جين BCS1L المسؤولة عن نقص معقد الميتوكندريا الثالث، الذي يسبب اعتلالات عصبية وكبدية وكلوية خطيرة.
| Feature | Our Test (BCS1L NGS – ISO Lab) | Closest Alternative (Standard Single-Gene Sequencing) |
|---|---|---|
| Precision | Detection of SNVs, indels, and copy number variants with >99.9% analytical sensitivity | May miss deep intronic or regulatory mutations; lower coverage uniformity |
| Methodology | NGS (Next Generation Sequencing) on Illumina platform with full bioinformatic alignment to GRCh38 | Sanger sequencing – limited to exons, no CNV analysis |
| Turnaround Time | 3–4 Weeks from sample receipt | 6–8 Weeks |
| Price (AED) | 2,800 | ~3,500 |
Physician Insight & Safety Protocol
“As a Neurologist, I recognize that a positive BCS1L result can be emotionally devastating for families. This report must be interpreted in the full clinical context—neuroimaging, biochemical markers, and family history—to guide realistic management plans. Please remember that genetic mutations do not always predict disease severity, and supportive care options have advanced significantly.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011, Specialist Neurologist
Medication Warning:
Do not discontinue or adjust any prescribed medication without explicit consultation with your treating physician. Certain drugs (e.g., valproic acid, aminoglycosides) may aggravate mitochondrial dysfunction; always inform your doctor before testing.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unstable due to acute metabolic decompensation (pH <7.2, hyperammonemia) must be stabilized before sample collection.
- Exclusion: Known interfering substances: recent heparinized sample without proper DNA extraction may inhibit sequencing. Use EDTA whole blood or FTA card.
- Red Flag Symptoms (seek immediate ER): Acute encephalopathy, seizures unresponsive to benzodiazepines, sudden loss of developmental milestones, severe lactic acidosis (lactate >5 mmol/L), or stroke-like episodes.
- Pre-test Information: A detailed clinical history and a formal genetic counselling session to draw a pedigree chart of affected family members is mandatory. This ensures appropriate variant classification and cascade testing.
Patient FAQ & Clinical Guidance
What does the BCS1L NGS test detect, and how long do results take?
Our comprehensive NGS test identifies pathogenic single-nucleotide variants, small deletions/insertions, and exon-level copy number changes across all coding exons of the BCS1L gene, with results delivered in 3 to 4 weeks.
يكشف اختبارنا الشامل عن الطفرات الجينية المسببة للأمراض في جميع إكسونات جين BCS1L، وتظهر النتائج خلال 3 إلى 4 أسابيع.
Is a home blood collection service available throughout the UAE?
Yes, we offer DHA-licensed mobile phlebotomy with ISO-certified cold-chain transport from 8 AM to 11 PM, covering all emirates, including Dubai, Abu Dhabi, Sharjah, and the Northern Emirates.
نوفر خدمة سحب عينات منزلية معتمدة من هيئة الصحة بدبي مع نقل بسلسلة تبريد معتمدة، تغطي جميع إمارات الدولة من الساعة 8 صباحاً حتى 11 مساءً.
Will my insurance cover this genetic, and how is my data protected?
Many UAE insurers partially or fully reimburse diagnostic mitochondrial genetic testing; we verify your coverage via WhatsApp before sample collection, and all genetic data is secured under UAE Federal Decree-Law No. 41 of 2024 (Art. 87) and the Personal Data Protection Law (PDPL).
تغطي العديد من شركات التأمين في الإمارات تكاليف هذا الفحص التشخيصي؛ نتحقق من تغطيتك عبر واتساب، وتُحمى بياناتك الجينية بموجب المرسوم الاتحادي رقم 41 لسنة 2024 وقانون حماية البيانات الشخصية.
Facility License No.: 9834453 | ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139)
Methodology: Next Generation Sequencing (NGS) with Illumina chemistry, GRCh38 alignment, and ACMG 2026 variant interpretation guidelines.
ICD-10-CM Codes (2026): E88.49 (Other mitochondrial metabolism disorders), G31.81 (Mitochondrial encephalopathy), Z15.09 (Genetic susceptibility to other disease).
LOINC Code: 93336-6 (BCS1L gene mutations found in Blood or Tissue by Molecular genetics method).
Intended Specialties: Neurologists, Clinical Geneticists, and Mitochondrial Medicine Specialists.
Legal Compliance: This service adheres to Federal Decree-Law No. 41 of 2024 (Art. 87) regarding confidentiality of genetic tests, the CDS Law 2026 for minors, and the UAE PDPL for genomic data privacy. Samples are processed in an ISO 9001:2015 and DHA-licensed facility.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians