Test Price
2,800 AED✅ Home Collection Available
AVPR2 Gene NSIAD Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, Available daily from 8 AM to 11 PM by DHA-licensed phlebotomists.
- Clinical Guidance: Telephonic Post-Test Consultation with a Consultant Medical Geneticist for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This next-generation sequencing (NGS) test comprehensively screens the entire coding region of the AVPR2 gene to detect pathogenic variants responsible for nephrogenic syndrome of inappropriate antidiuresis (NSIAD), a rare X-linked disorder causing water retention and hyponatremia. The method provides full exon coverage and bioinformatics analysis for variant classification.
| Feature | Our Test (AVPR2 NGS) | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity | ~95% (Sanger sequencing—limited variant detection) |
| Methodology | NGS with full exon coverage and bioinformatics analysis | Sanger sequencing (single-exon analysis) |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics (DHA: 9294403): “Identifying a pathogenic AVPR2 variant confirms NSIAD, but clinical correlation with serum sodium, plasma osmolality, and family history remains essential to differentiate from SIADH or other hyponatremic states. This NGS test enables precise diagnosis and targeted management, reducing unnecessary fluid restrictions or empirical drug trials.”
Clinical Advisory: Medication Interaction Awareness
Do not discontinue or adjust any prescribed medication without consulting your physician. Certain drugs (e.g., carbamazepine, SSRIs) can mimic or exacerbate hyponatremia; always inform your doctor of all current therapies before undergoing genetic testing.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unable to provide valid genetic counselling consent or with a known interfering blood transfusion within the past 7 days.
- Red Flag – Seek Immediate Medical Attention: Sudden severe headache, confusion, seizures, or altered consciousness—symptoms of acute hyponatremic encephalopathy.
- Red Flag: Serum sodium <120 mmol/L or a rapid drop of >10 mmol/L in 24 hours requires urgent hospital evaluation.
Patient FAQ & Clinical Guidance
1. What exactly does the AVPR2 gene NSIAD NGS test detect, and who needs it?
This advanced next-generation sequencing test detects pathogenic variants in the AVPR2 gene causing nephrogenic syndrome of inappropriate antidiuresis. It is indicated for individuals with unexplained hyponatremia, low plasma osmolality, and normal adrenal and thyroid function.
2. How is the sample collected, and is home service available in the UAE?
A simple venous blood draw is collected via our VIP mobile phlebotomy service, available daily from 8 AM to 11 PM across all emirates. The sample is transported under temperature-controlled cold chain to our accredited laboratory.
3. What is the turnaround time, and does insurance cover the 2800 AED cost?
Results are delivered within 3 to 4 weeks at a fixed price of 2800 AED. We offer direct insurance billing verification via WhatsApp at +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
This diagnostic service fully complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring secure handling of genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing digital health data integrity.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – establishing patient safety and consent protocols.
Clinical & Logistical Metadata
| Test Name | AVPR2 Gene NSIAD Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA tube) |
| Methodology Used | Next-Generation Sequencing (NGS) – full gene coding region and splice sites |
| ICD-10-CM Code | E22.2 (Syndrome of inappropriate secretion of antidiuretic hormone) |
| LOINC Code | 91821-6 (AVPR2 gene full mutation analysis) |
| DHA Facility License & Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians