Test Price
2,800 AED✅ Home Collection Available
APOB Gene Hypercholesterolaemia Type B (Autosomal Dominant) Genetic Test in UAE – 2800 AED – DHA Licensed
Executive Summary & Core Metrics
This ISO‑accredited Next‑Generation Sequencing (NGS) test delivers 99.9% diagnostic sensitivity for APOB gene mutations causing autosomal dominant familial hypercholesterolaemia type B. Services include VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection (available daily from 8 AM to 11 PM), direct billing verification via WhatsApp (+971 54 548 8731), and telephonic clinical guidance on result interpretation by DHA‑licensed specialists.
- Accuracy: 99.9% Diagnostic Sensitivity – ISO 9001:2015 Processing
- Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection
- Support: WhatsApp Direct Billing & Clinical Guidance: +971 54 548 8731
- Clinician Review: Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA 9294403
Test Overview & Methodology
This NGS‑based genetic test analyzes the entire coding region of the APOB gene to identify pathogenic variants linked to autosomal dominant hypercholesterolaemia type B, a condition that severely elevates LDL‑cholesterol and accelerates cardiovascular disease. The assay replaces outdated Sanger‑based screening with clinically validated NGS at 300× mean coverage, enabling precise risk stratification and cascade testing for at‑risk family members.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | NGS with 99.9% analytical specificity | Single‑variant genotyping; lower sensitivity |
| Method | Next‑Generation Sequencing (full gene) | Polymerase Chain Reaction (PCR) for specific loci |
| Turnaround | 3–4 weeks with ISO‑validated bioinformatics | 4–6 weeks; limited variant interpretation |
| UAE Compliance | DHA‑approved, Federal Decree‑Law No. 45 of 2021 (PDPL) & Federal Law No. 2 of 2019 aligned | Often lacks full PDPL and health data protection frameworks |
Physician Insight & Safety Protocols
“I understand that awaiting a genetic result about familial hypercholesterolaemia can feel overwhelming. Please remember that a positive result is a powerful tool enabling targeted prevention and personalised treatment. This test must be interpreted alongside your lipid profile and family history, never in isolation. If you experience any new chest discomfort or neurological symptoms, seek immediate medical attention.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Medication Warning
Do not discontinue any prescribed cholesterol‑lowering medication (e.g., statins, ezetimibe) without consulting your doctor. Abrupt cessation can cause dangerous lipid rebound and acute cardiovascular events.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Acute febrile illness or active infection at time of blood draw
- Exclusion: Known severe coagulopathy or anti‑coagulant therapy without clearance
- Exclusion: Genetic testing of minors requires documented clinical necessity and parental consent in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability
- Emergency Red Flags: Sudden crushing chest pain, shortness of breath, loss of balance, or facial drooping following genetic counseling – call 998 immediately
Patient FAQ & Clinical Guidance
1. What is the APOB gene hypercholesterolaemia type B test?
This NGS‑based genetic test identifies pathogenic variants in the APOB gene causing autosomal dominant familial hypercholesterolaemia type B, enabling precise cardiovascular risk stratification and early intervention.
2. How is the sample collected and what is the turnaround time?
A single blood draw, extracted DNA, or a dried blood spot on an FTA card is collected via VIP mobile phlebotomy with temperature‑controlled cold‑chain home collection (available daily from 8 AM to 11 PM), with results reported in 3 to 4 weeks.
3. Is this test suitable for children?
Genetic testing for minors requires documented clinical necessity and parental consent as per Federal Decree‑Law No. 4 of 2016 on Medical Liability. We strictly adhere to this legal mandate; no sample will be accepted without proper documentation.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance
DNA Labs UAE operates under DHA Facility License 1143. All genetic data is handled in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and confidentiality are paramount, with strict protocols for data storage, access, and sharing. Our laboratory adheres to the highest standards of ethical and legal practice in the UAE.
Clinical & Logistical Metadata
| Test Name | APOB Gene Hypercholesterolaemia Type B (Autosomal Dominant) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or dried blood spot on FTA card |
| Methodology Used | Next‑Generation Sequencing (NGS) – full gene coding region, 300× coverage |
| ICD-10-CM Code | E78.01 |
| LOINC Code | 94046-6 |
| DHA Facility License & Address | DHA Facility License: 1143 DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians