Test Price
2,800 AED✅ Home Collection Available
ALS2 Gene (Amyotrophic Lateral Sclerosis Type 2, Juvenile) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited NGS Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain, including VIP Mobile Phlebotomy (available daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The ALS2 gene NGS test screens for pathogenic variants linked to juvenile-onset amyotrophic lateral sclerosis (JALS), enabling early neurological intervention. This test analyzes the entire coding region using Next Generation Sequencing with >99% sensitivity, providing a definitive molecular diagnosis in 3–4 weeks.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | >99% Sensitivity (Full Exon NGS) | Limited to known variants (Sanger Sequencing) |
| Method | Next Generation Sequencing (NGS) | Targeted Sanger Sequencing |
| Speed | 3 – 4 Weeks TAT | Up to 6 Weeks |
Physician Insight & Safety Protocols
A positive result confirms genetic susceptibility but does not diagnose clinical ALS; it must be interpreted alongside neurological examination and family history. As a consultant in medical genetics, I emphasize that this test is a powerful tool for early risk stratification, especially in families with juvenile-onset motor neuron disease. Always consult with a genetic counselor before testing.
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)
Clinical Advisory
Post-Test Genetic Counseling
All patients receiving a pathogenic or likely pathogenic result are strongly advised to attend a post-test genetic counseling session. Our team coordinates with DHA-licensed genetic counselors to discuss implications for family planning, cascade screening, and long-term neurological monitoring.
Safety & Exclusion Criteria
- Exclusion Criteria: Active infections, recent blood transfusion (may affect DNA extraction); severe anemia requiring immediate treatment.
- ER Red Flags: If the patient develops acute respiratory distress, swallowing difficulties, or rapid muscle weakness, seek emergency care immediately. This genetic test is not a substitute for urgent neurological evaluation.
- Home collection is performed by DHA-licensed phlebotomists; always inform the team of any bleeding disorders or anticoagulant use.
Patient FAQ & Clinical Guidance
1. What does the ALS2 gene test detect?
The ALS2 gene test detects pathogenic mutations in the ALS2 gene that cause juvenile amyotrophic lateral sclerosis, enabling targeted family screening. These mutations are associated with a rapidly progressive, early-onset form of motor neuron disease. Understanding your genetic status allows neurologists and genetic counsellors to tailor surveillance and support for at-risk family members.
2. How is the sample collected and what is the turnaround time?
Sample collection is via a simple blood draw or FTA card at home between 8 AM and 11 PM, with results available in 3–4 weeks using Next Generation Sequencing. A DHA-licensed phlebotomist arrives with full cold-chain transport. The lab extracts DNA and performs full exon analysis, ensuring minimal false negatives. You may choose whole blood, extracted DNA, or a heel-prick dried blood spot on an FTA card.
3. Is this covered by insurance in the UAE?
Many UAE insurers cover ALS2 genetic testing when medically indicated, and we verify your coverage directly via WhatsApp before the appointment. Our team coordinates with Daman, ADNIC, Nextcare, and all major networks to obtain pre-approval. Contact +971 54 548 8731 with your Emirates ID and insurer details for a quick verification.
UAE Regulatory & Data Privacy Adherence
Your Data is Protected Under UAE Federal Law
DNA Labs UAE operates under DHA Facility License No. 1143 and strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, stored securely, and never shared without explicit consent. Clinical safety and patient consent are further governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | ALS2 Gene (Juvenile ALS) Sequencing |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) – Full Coding Region |
| ICD-10-CM Code | G12.21 |
| LOINC Code | 29527-8 |
| DHA Facility License & Laboratory Address | License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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