Test Price
2,800 AEDโ Home Collection Available
ALDH2 Gene Acute Alcohol Sensitivity Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post-Test Clinical Guidance included in the pre-counselling session.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The ALDH2 Gene Acute Alcohol Sensitivity Genetic Test detects functional variants in the ALDH2 gene to assess an individualโs ability to metabolize acetaldehyde, the toxic intermediate of alcohol. This test utilises Next-Generation Sequencing (NGS) to comprehensively analyse the entire coding region, capturing both common polymorphisms such as rs671 and rare or novel variants that influence enzyme activity.
| Feature | Our Test (NGS) | Closest Alternative (PCR-based Genotyping) |
|---|---|---|
| Molecular Resolution | Whole gene coverage โ detects rare and novel variants | Limited to predefined common SNPs (e.g., rs671) |
| Analytical Sensitivity | Greater than 99.9% at 100x depth | Approximately 95% for targeted alleles |
| Turnaround Time | 21โ28 Days (comprehensive analysis) | 5โ7 Days |
| Clinical Report | DHA-compliant laboratory report with interpretation guidance | Basic genotype call without full metabolic interpretation |
Physician Insight & Safety Protocols
โThe ALDH2 test serves as a powerful preventive tool for patients of East Asian descent and others who experience alcohol-induced flushing. A definitive genetic result empowers clinicians to offer personalised advice on alcohol intake, drug safety, and cancer screening. I always remind patients that the result should be correlated with a complete clinical history and never used in isolation. โ Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403)โ
Medication Advisory
Important Medication Interaction Warning
Always consult your prescribing physician before discontinuing any medication. Certain drugs including antihistamines, sulfonylurea antidiabetics, and nitrate-based cardiovascular therapies can interact with elevated acetaldehyde levels, potentially amplifying side effects such as flushing, headache, or hypotension.
Safety Exclusion Criteria
Who Should Not Proceed with Testing
- Individuals who have received an allogeneic bone marrow or stem cell transplant within the preceding 6 months (donor-derived DNA may confound germline results).
- Patients with an active hematologic malignancy where circulating blasts exceed 20% (may compromise leukocyte DNA integrity).
- Pregnant women โ non-urgent genetic testing is generally deferred until the postpartum period in accordance with UAE clinical ethics guidelines.
Emergency Red Flags
- Seek immediate medical attention if accidental alcohol ingestion results in severe facial flushing, palpitations, and hypotension that do not respond to antihistamines.
- Never self-administer disulfiram or disulfiram-like supplements without a formal prescription and direct physician oversight.
All results must be interpreted by a licensed genetic counsellor or physician. A genetic consultation is included as part of the pre-test counselling session.
Patient FAQ & Clinical Guidance
1. What does a positive ALDH2 deficiency result mean for my daily life?
A positive result confirms that your body has a reduced capacity to break down acetaldehyde, the toxic byproduct of alcohol metabolism. This places you at higher risk for alcohol-induced facial flushing, nausea, tachycardia, and a well-documented increased long-term susceptibility to certain cancers, particularly oesophageal squamous cell carcinoma.
2. How reliable is the NGS method compared to older PCR-based testing?
Our NGS technology delivers an analytical sensitivity exceeding 99.9% at 100x sequencing depth. It identifies both common variations such as rs671 and rare or previously unreported ALDH2 mutations, whereas PCR-based genotyping is confined to a small set of predefined alleles and may miss up to 5% of clinically relevant variants.
3. Is home blood collection safe and how does it meet UAE regulatory standards?
Yes. Our ISO 9001:2015 certified mobile phlebotomy service adheres to strict cold-chain transportation protocols and is performed by trained professionals. It fully complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
4. Will my insurance cover the cost of this genetic test?
Coverage varies by insurance provider and policy. Our team can verify your direct billing eligibility via WhatsApp at +971 54 548 8731. Please have your policy number and Emirates ID ready for verification.
5. How long will it take to receive my results and how are they delivered?
The turnaround time is 21 to 28 days from sample receipt. This includes comprehensive NGS analysis, bioinformatic interpretation, and medical review. Results are delivered as a secure digital PDF report compliant with DHA standards, accompanied by a telephonic post-test guidance session with a genetics professional.
UAE Regulatory & Data Privacy Adherence
Commitment to UAE Legal Frameworks
All genetic testing procedures at DNA Labs UAE are conducted in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ ensuring your genetic data is collected, processed, and stored with the highest privacy safeguards.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ governing the secure handling of electronic health records and telemedicine interactions.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ upholding patient consent, clinical safety, and accountability in all diagnostic procedures.
Your data belongs to you. We never share identifiable genetic information without your explicit written consent.
Clinical & Logistical Metadata
| Test Name | ALDH2 Gene Acute Alcohol Sensitivity Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 21โ28 Days |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Next-Generation Sequencing (NGS) โ Whole Gene Coverage |
| ICD-10-CM Code | Z13.89 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians