Test Price
2,800 AEDโ Home Collection Available
AGTR1 Gene Renal Tubular Dysgenesis Genetic Test in UAE | AED 2800 | DHA Licensed Laboratory
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139)
- Premium Logistics: Hospital-Grade Home Collection with ISO-Certified Cold-Chain & VIP Mobile Phlebotomy, available 8 AM โ 11 PM
- Clinical Guidance: Telephonic PostโTest Clinical Interpretation with a Consultant Medical Genetics specialist
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
- Regulatory Compliance: Full adherence to UAE Federal Decree-Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019 for health data protection
Test Overview & Methodology
The AGTR1 Gene Genetic Test identifies pathogenic mutations in the angiotensin II receptor type 1 gene that cause autosomal recessive renal tubular dysgenesis โ a severe congenital kidney disorder. This advanced molecular diagnostic test enables precise diagnosis, family risk assessment, and informed clinical management. Next-generation sequencing (NGS) provides comprehensive coverage of the entire AGTR1 coding region with high depth, detecting single nucleotide variants, small insertions/deletions, and splice-site alterations that may be missed by conventional methods.
| Feature | Our Test โ AGTR1 NGS DNA | Closest Alternative โ Sanger Sequencing |
|---|---|---|
| Methodology | Next Generation Sequencing (targeted, high depth) | Sanger sequencing of individual exons |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| Diagnostic Yield | 99.9% sensitivity (variant confirmation included) | ~95% for coding mutations; may miss deep intronic variants |
| Clinical Utility | Comprehensive gene coverage, ideal for carrier screening & family planning | Limited variant resolution; not optimal for broad family mutation screening |
Physician Insight & Safety Protocols
โAs a Consultant Medical Genetics specialist, I recognise the profound impact that a genetic diagnosis of renal tubular dysgenesis can have on a family. This AGTR1 NGS test delivers definitive variant identification, empowering nephrologists and genetic counsellors to provide accurate recurrence risk counselling and guide reproductive decision-making. Always correlate results with full clinical evaluation and family history.โ
โ Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Important Advisory
โ ๏ธ Do not discontinue prescribed medications or alter renal management without consulting your treating physician. This test is a complement to โ not a replacement for โ comprehensive clinical assessment by a qualified nephrologist or geneticist.
Exclusion Criteria & Emergency Red Flags
- Not suitable for individuals who have received a bone marrow transplant within the last 6 weeks (donor DNA interference may compromise results).
- Patients with platelet count <50,000/ยตL must obtain haematology clearance prior to venipuncture.
- Testing for minors requires valid parental/guardian consent as per UAE Federal Law No. 2 of 2019.
- Seek emergency care immediately if you experience severe bleeding, fainting, or signs of infection at the blood collection site.
Patient FAQ & Clinical Guidance
1. What is the AGTR1 gene test used for?
AGTR1 NGS test detects mutations that cause renal tubular dysgenesis, aiding early diagnosis and family planning. It screens the entire coding region of the AGTR1 gene using next-generation sequencing to identify disease-causing variants responsible for severe kidney maldevelopment, helping nephrologists and geneticists tailor management and reproductive options.
2. How is the sample collected and is it painful?
Home sample collection uses a standard blood draw or non-invasive FTA card, ensuring comfort and sterility. A certified phlebotomist arrives at your location with temperature-controlled cold-chain transport; most patients report minimal discomfort comparable to a routine blood test.
3. What do the results mean for my family?
Results identify if you carry a pathogenic AGTR1 mutation, guiding reproductive choices and family screening. If a mutation is found, genetic counselling can clarify inheritance risks for siblings and future children, and discuss options such as prenatal diagnosis or preimplantation genetic testing.
4. How long does it take to get results?
The turnaround time is 3โ4 weeks from sample reception. This allows for comprehensive NGS processing, bioinformatic analysis, variant confirmation by Sanger sequencing when required, and detailed reporting with clinical interpretation by a Consultant Medical Genetics specialist.
5. Is genetic counselling provided with this test?
Yes, telephonic post-test clinical interpretation is included with every test. A genetic specialist will discuss your results, explain inheritance patterns, and provide guidance on next steps for you and your family members.
UAE Regulatory & Data Privacy Adherence
โ This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, accessโcontrolled, and processed under strict confidentiality agreements. Clinical safety and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | AGTR1 Gene Renal Tubular Dysgenesis Genetic Test (NGS) |
| Price (AED) | AED 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or FTA Card โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily 8 AM โ 11 PM |
| Methodology Used | Next Generation Sequencing (Targeted, High Depth) with Sanger Confirmation |
| ICD-10-CM Code | Q61.4 |
| LOINC Code | 90507-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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