Test Price
2,800 AED✅ Home Collection Available
ADK Gene Hypermethioninemia due to Adenosine Kinase Deficiency: NGS Genetic Test
Executive Summary & Core Metrics
Executive Summary – ADK Gene Test
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited next-generation sequencing.
- Premium Logistics: VIP mobile phlebotomy & temperature-controlled cold-chain home collection available daily (8 AM – 11 PM).
- Clinical Guidance: Post-test telephonic interpretation by qualified clinical geneticists.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
99.9%
Diagnostic Sensitivity
3-4 Weeks
Turnaround Time
2,800 AED
Test Price
ISO 9001:2015
Accredited Lab
Test Overview & Methodology
The ADK Gene NGS Test uses advanced next-generation sequencing to analyse the entire coding region of the adenosine kinase (ADK) gene, identifying pathogenic variants that cause hypermethioninemia and associated multisystemic features. Comprehensive coverage detects even rare mutations, enabling precise diagnosis, carrier screening, and personalised management.
| Feature | Our Test (ADK Gene NGS) | Closest Alternative (Plasma Methionine) |
|---|---|---|
| Method | Next‑Generation Sequencing (full gene) | Biochemical assay of methionine/homocysteine |
| Diagnostic precision | >99.9% sensitivity for coding SNVs/indels | Reflects metabolic status, can miss attenuated cases |
| Turnaround Time | 3‑4 Weeks (ISO‑controlled workflow) | 1‑3 Days |
| Clinical Utility | Definitive genetic diagnosis, family screening, recurrence risk | Screening tool; requires confirmatory genetic test |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics certified by the DHA (License No. 9294403) with extensive expertise in inborn errors of metabolism, I understand the profound concern a suspected hypermethioninemia diagnosis can cause for you and your family. A positive result must always be interpreted alongside clinical symptoms, biochemical profiles, and imaging findings. Please use this genetic information as a powerful tool to guide care, not as an isolated verdict.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics
Advisory: Medication Continuation & Medical Consultation
⚠️ Important: Do not discontinue or alter any prescribed medication based on genetic test results without direct consultation with your treating physician. Test results provide diagnostic information and are not a substitute for medical advice.
Exclusion Criteria & Safety Red Flags
- Exclusion Criteria: This test is not suitable for patients requiring acute emergency intervention; it is an outpatient diagnostic/screening service. Venous access failure or active infection at the draw site may temporarily delay sample collection.
- Emergency Red Flags: If the patient develops sudden lethargy, poor feeding, seizures, respiratory distress, or an altered mental state, seek immediate emergency care and postpone routine genetic testing.
- Minors: Testing of minors requires explicit informed consent from a legal guardian in compliance with UAE Child Protection Law (Wadeema’s Law) and Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What exactly does the ADK gene NGS test detect?
This test sequences the entire coding region of the ADK gene to identify DNA variants responsible for adenosine kinase deficiency and hypermethioninemia. It detects single nucleotide variants and small insertions/deletions with >99.9% sensitivity.
2. How should I prepare for the blood draw and what does pre-test counselling involve?
You will receive a complimentary genetic counselling session to draw a detailed pedigree chart, review your clinical history, and ensure informed consent before the blood sample is taken. No special preparation is needed beyond routine hydration.
3. Is my genetic data protected under UAE law?
Yes, all genetic information is strictly safeguarded under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Data is processed only in ISO‑certified facilities with strict access controls.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance Framework
Your genetic data is handled in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL)
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Federal Decree-Law No. 4 of 2016 on Medical Liability (ensuring informed consent and clinical safety)
DNA Labs UAE is ISO 9001:2015 certified and operates under DHA Facility License No. 1143, adhering to the highest standards of quality and data security.
Clinical & Logistical Metadata
| Test Name | ADK Gene Hypermethioninemia (Adenosine Kinase Deficiency) NGS Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks (ISO-controlled workflow) |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL EDTA tube) |
| Methodology Used | Next‑Generation Sequencing (Targeted Capture & High‑Throughput Sequencing) |
| ICD-10-CM Code | E72.11 (Hypermethioninemia) |
| LOINC Code | 101404-3 |
| DHA Facility License & Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians