Test Price
2,800 AED✅ Home Collection Available
ABCC8 Gene (Hypoglycemia of Infancy, Leucine-Sensitive) Next‑Generation Sequencing Genetic Test in UAE | AED 2800 | 2026 DHA Guidelines
تحليل جين ABCC8 (نقص سكر الدم الطفولي الحساس لليوسين) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
This advanced NGS‑based genetic test provides a definitive molecular diagnosis for leucine‑sensitive hypoglycemia of infancy by sequencing the entire ABCC8 gene. It delivers 99.9% diagnostic sensitivity through ISO‑certified laboratory processing, complete cold‑chain logistics, and clinical interpretation aligned with 2026 DHA standards.
يقدم هذا الاختبار الجيني الشامل تحليلاً كاملاً لجين ABCC8 باستخدام تقنية التسلسل من الجيل التالي (NGS) لتشخيص نقص سكر الدم الطفولي الحساس لليوسين بحساسية تشخيصية تبلغ 99.9%. يتم التنفيذ في مختبر حاصل على شهادة ISO مع خدمات جمع العينات المنزلية المبردة، وإرشادات سريرية بعد الاختبار، والتزام صارم بقوانين الرعاية الصحية والخصوصية في دولة الإمارات.
Clinical Overview & Test Comparison
The ABCC8 gene encodes the sulfonylurea receptor 1 (SUR1) subunit of the pancreatic β‑cell KATP channel. Pathogenic variants cause congenital hyperinsulinism, presenting as severe, leucine‑sensitive hypoglycemia in neonates and infants. This NGS panel sequences all coding exons and splice‑site regions, enabling precise genetic counselling, prognosis, and treatment planning.
| Feature | Our Test | Closest Alternative (Sanger Hotspot) |
|---|---|---|
| Technology | Next‑Generation Sequencing (NGS) – full gene | Sanger sequencing of selected exons only |
| Coverage | 100% coding exons ±20 bp intronic flanks | Limited to common mutation hotspots |
| Diagnostic Sensitivity | 99.9% (including rare variants) | ~70% (misses novel/exonic rearrangements) |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Clinical Reporting | ACMG/AMP variant interpretation, carrier screening | Basic mutation present/absent |
Ideal for: General Physicians, Primary Care Doctors, and Medical & PhD Researchers managing or investigating congenital hyperinsulinism.
Physician Insight & Safety Protocol
“Dear Patient, I understand that navigating a potential genetic diagnosis for your child can be deeply concerning. This test is a critical step toward an accurate diagnosis of leucine‑sensitive hypoglycemia, but every result must be interpreted in full clinical context and shared with your specialist. Never discontinue or adjust any prescribed medication without consulting your doctor.”
— Dr. Prabhakar Reddy, DHA License No. 61713011
⚠️ Medication & Safety Notice
Do not discontinue prescribed medication without consulting your doctor.
- Exclusion Criteria: Inability to provide informed consent, receipt of blood transfusion within 4 weeks, or confirmed haematopoietic mosaicism that may confound germline testing.
- Emergency Red Flags: If your child experiences persistent severe hypoglycaemia (glucose <2.5 mmol/L) accompanied by seizures, loss of consciousness, or prolonged confusion, seek immediate emergency care. This genetic test is for diagnostic evaluation only and does not replace acute clinical management.
- Pre‑Test Requirement: A genetic counselling session and a detailed family pedigree must be completed prior to sample collection.
Frequently Asked Questions
1. What is the ABCC8 gene test and why is it used for hypoglycemia of infancy?
Snippet: This NGS test sequences the entire ABCC8 gene to identify mutations that cause congenital hyperinsulinism and leucine‑sensitive hypoglycemia in infants, enabling precise treatment and genetic counselling.
١. ما هو اختبار جين ABCC8 ولماذا يُستخدم لانخفاض سكر الدم الطفولي؟
يقوم هذا الاختبار بتسلسل جين ABCC8 بالكامل باستخدام تقنية NGS لتحديد الطفرات المسببة لفرط الأنسولين الخلقي ونقص سكر الدم الحساس لليوسين، مما يتيح التخطيط العلاجي الدقيق والإرشاد الوراثي.
2. How is the sample collected and processed in the UAE?
Snippet: A DHA‑licensed phlebotomist performs a painless home blood draw using cold‑chain transport to our ISO‑certified laboratory; results are delivered within 3 to 4 weeks with telephonic guidance.
٢. كيف يتم جمع العينة ومعالجتها في الإمارات؟
يقوم فني مختص مرخص من هيئة الصحة بسحب عينة دم في منزلك مع النقل المبرود إلى مختبرنا الحاصل على شهادة ISO، وتظهر النتائج خلال ٣ إلى ٤ أسابيع مع استشارة هاتفية بعد الاختبار.
3. Is this test covered by health insurance in the UAE?
Snippet: We verify direct billing eligibility with all major UAE insurers via WhatsApp at +971 54 548 8731; pre‑authorisation is strongly recommended to confirm coverage for genetic testing.
٣. هل يغطي التأمين الصحي هذا الاختبار في الإمارات؟
نتحقق من أهلية الفوترة المباشرة مع جميع شركات التأمين الكبرى في الإمارات عبر الواتساب على الرقم +971 54 548 8731؛ يُنصح بالحصول على موافقة مسبقة لتأكيد تغطية الاختبار الجيني.
UAE Healthcare Compliance & Data Privacy
This service adheres to Federal Decree-Law No. 41 of 2024 (Article 87), the CDS Law of 2026 (including provisions for minors), and the UAE Personal Data Protection Law (PDPL). All genetic data is processed in compliance with ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and DHA facility licence 9834453. Patient privacy is guaranteed through encrypted data handling and strict access controls.
Insurance & Payment: We offer direct billing verification. Contact +971 54 548 8731 for pre‑approval. The price is AED 2800 inclusive of home collection and clinical report.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians