Test Price
2,800 AED✅ Home Collection Available
ABCC2 Gene Dubin-Johnson Syndrome Genetic Test in UAE | NGS | 2800 AED
Executive Summary & Core Metrics
Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Turnaround Time: 3–4 Weeks from sample receipt.
Test Overview & Methodology
The ABCC2 Gene NGS Test detects mutations causing Dubin-Johnson syndrome, a benign hereditary hyperbilirubinemia. This advanced sequencing provides comprehensive analysis of the entire ABCC2 gene, ensuring accurate diagnosis and family risk assessment. Next-Generation Sequencing (NGS) is employed to analyze all exons and flanking regions, delivering high sensitivity and specificity.
| Parameter | Our Test (NGS Precision) | Alternative (Sanger Sequencing) |
|---|---|---|
| Method | Next-Generation Sequencing (NGS) | Sanger Sequencing |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Detection Sensitivity | 99.9% | ~95% |
| Price | 2,800 AED | 3,500 AED |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I recognize that genetic testing for Dubin-Johnson syndrome can be reassuring for families. This benign condition rarely causes liver damage, yet understanding your genetic blueprint empowers you. I strongly recommend correlating these results with clinical findings and never discontinuing any prescribed medications without medical supervision.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Genetic test results should always be interpreted alongside clinical and laboratory findings. Consult your healthcare provider before making any changes to your treatment plan.
Exclusion Criteria & Emergency Red Flags
- Individuals under 18 without legal guardian consent.
- Current acute illness (e.g., high fever, sepsis) that may interfere with genetic counseling.
- Uncontrolled psychiatric condition preventing informed consent.
Seek immediate medical attention if you experience:
- Sudden severe jaundice with confusion or altered mental status.
- Intense abdominal pain or swelling.
- Signs of bleeding, bruising, or encephalopathy.
Patient FAQ & Clinical Guidance
1. What is Dubin-Johnson syndrome and how is it inherited?
Dubin-Johnson syndrome is an autosomal recessive disorder caused by ABCC2 gene mutations, leading to benign conjugated hyperbilirubinemia. It is inherited when both parents carry a mutated copy; carriers are typically asymptomatic. The condition does not require treatment, but diagnosis prevents unnecessary investigations for other liver diseases.
2. What does the ABCC2 NGS test involve?
A blood sample drawn by our home collection team is processed using next-generation sequencing to analyze all exons of the ABCC2 gene. The test covers known and rare mutations, delivering a comprehensive report within 3–4 weeks. No fasting is required, and you can continue your normal routine before the draw.
3. How should I prepare for the test?
No fasting or medication adjustments are necessary, but inform your clinician of all health conditions and continue prescribed treatments. A genetic counseling session will be arranged to draw a family pedigree and explain the implications. Please have a list of any relatives with jaundice or liver conditions ready.
4. What is the turnaround time for results?
Results are typically available within 3–4 weeks after sample collection. You will receive a detailed report via secure electronic delivery along with a telephonic consultation to explain the findings.
5. Is the test covered by insurance?
Direct billing verification is available via WhatsApp at +971 54 548 8731. Coverage depends on your insurance plan; our team can help pre-authorize the test before sample collection.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Health Information Protection
Our laboratory operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, stored securely, and accessed only by authorized personnel. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
DNA Labs UAE is licensed by the Dubai Health Authority (DHA License No. 1143) and adheres to the highest standards of quality and confidentiality.
Clinical & Logistical Metadata
| Test Name | ABCC2 Gene NGS Test for Dubin-Johnson Syndrome |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (3–5 mL in EDTA tube) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene sequencing of ABCC2 |
| ICD-10-CM Code | E80.6 |
| LOINC Code | 69047-9 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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