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Test Price

2,800 AED

✅ Home Collection Available

TLR3 Gene Herpes Simplex Encephalitis Type 2 Susceptibility Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

Advanced NGS-based genetic test evaluating the TLR3 gene for pathogenic variants that increase susceptibility to herpes simplex encephalitis type 2 (HSV-2 E). Delivers 99.9% diagnostic sensitivity through ISO-accredited processing with temperature-controlled cold-chain logistics.

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM–11 PM).
  • Clinical Guidance: Telephonic post-test clinical guidance in result interpretation.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This next-generation sequencing (NGS) assay interrogates the entire coding region and splice junctions of the TLR3 gene to identify loss-of-function mutations predisposing to HSV-2 encephalitis. Results are interpreted by board-certified clinical geneticists and integrated with patient history for personalised surveillance protocols.

Feature Our Test (TLR3 NGS) Conventional Genetic Screening
Precision High-depth NGS with variant‑specific sensitivity >99.9% Limited Sanger sequencing; may miss large deletions
Methodology Next Generation Sequencing; confirmed by orthogonal Sanger validation Targeted PCR or single‑exon sequencing
Turnaround 3 to 4 Weeks (guaranteed cold‑chain integrity) 4–6 Weeks typical; no ISO logistics

Physician Insight & Safety Protocols

“A genetic predisposition for HSV-2 encephalitis revealed by this test must be integrated with full clinical and neurological evaluation. This result is a starting point for personalised surveillance, not a definitive diagnosis. Patients should discuss findings with a specialist to define a protective health plan.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403)

⚠️ Advisory – Strict Pre-Test Compliance

Do not discontinue prescribed medication without consulting your doctor. Antivirals or immunosuppressants must be reported to the collecting phlebotomist.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Active herpetic skin lesions requiring immediate antiviral therapy; inability to provide blood or extracted DNA; hemodynamic instability.
  • Pre‑Test Requirement: Mandatory genetic counselling session; detailed pedigree chart of family members affected by or suspected of HSV‑2 encephalitis must be submitted.
  • ER Red Flags: If you experience sudden confusion, high fever with severe headache, seizures, or altered consciousness after sample collection, seek emergency medical care immediately. These may indicate acute encephalitis and are not caused by the blood draw.

Patient FAQ & Clinical Guidance

1. What does the TLR3 Herpes Encephalitis Susceptibility Test detect?

This test identifies pathologic variants in the TLR3 gene that increase the risk for herpes simplex encephalitis type 2, guiding risk management and surveillance strategies.

2. How should I prepare for the blood collection at home?

You do not need to fast; simply remain hydrated and inform our phlebotomist of all medications, especially antivirals or immunosuppressants.

3. Will my insurance cover this test and is genetic data protected?

Coverage is verified upfront via WhatsApp; all genetic data is secured under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning health information security.

UAE Regulatory & Data Privacy Adherence

Data Privacy & Health Information Governance: This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient genetic data is encrypted, access-controlled, and used solely for diagnostic and clinical guidance purposes. In accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability, informed consent is obtained before sample collection, specifying the scope of genetic analysis and data handling.

Clinical & Logistical Metadata

Test Name TLR3 Gene Herpes Simplex Encephalitis Type 2 Susceptibility (NGS)
Price (AED) 2,800 AED
Turnaround Time 3 to 4 Weeks (cold‑chain integrity guaranteed)
Sample Type / Matrix Peripheral whole blood (3–5 mL EDTA) or extracted genomic DNA (2 µg minimum)
Methodology Used Next-Generation Sequencing (NGS) with orthogonal Sanger validation
ICD-10-CM Code Z15.89 (Genetic susceptibility to other disease), Z86.19 (Personal history of infectious disease)
LOINC Code 48767-8 (TLR3 gene mutation analysis in Blood or Tissue by Molecular genetics method)
DHA Facility License & Address License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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