Test Price
2,800 AED✅ Home Collection Available
SOD2 Genetic Susceptibility Test for Diabetic Microvascular Complications (NGS) in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed medical geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (reply within 15 minutes).
Test Overview & Methodology
This advanced NGS-based test identifies the SOD2 rs4880 (Val16Ala) polymorphism to stratify an individual’s genetic risk for diabetic microvascular complications, including nephropathy, retinopathy, and neuropathy. Patients receive a bilingual laboratory report with lifetime risk scores and actionable clinical recommendations aligned with international guidelines and UAE regulatory standards.
| Feature | Our Test (SOD2 NGS) | Closest Alternative (PCR-based Genotyping) |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity via full‑gene NGS sequencing | 85–90% sensitivity; only targets the rs4880 SNP, missing adjacent pathogenic variants |
| Method | Next‑Generation Sequencing (Illumina® platform, 500× depth) | TaqMan® PCR or RFLP |
| Speed | 3–4 weeks (comprehensive bioinformatics & double‑locking clinical interpretation) | 1–2 weeks (raw genotype only, no phenotypic correlation) |
Physician Insight & Safety Protocols
“The SOD2 rs4880 polymorphism is a key modulator of mitochondrial antioxidant defense. A positive susceptibility result empowers early, targeted surveillance for diabetic microvascular complications. I always interpret this result within the full clinical context, including HbA1c, eGFR, and fundoscopic examination, to craft a truly personalised prevention plan.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Notice
⚠️ Important Medication Safety
Do not discontinue prescribed diabetes medication or alter your treatment plan without consulting your doctor. This genetic test is a complementary risk stratification tool and does not replace standard diabetes care, regular complication screening, or clinical judgment.
Exclusion Criteria & Emergency Red Flags
- Active acute hyperglycaemic crisis (HHS/DKA) or unstable medical condition – defer testing until stabilised.
- Known diagnosis of end‑stage renal disease (eGFR <15 mL/min) or advanced proliferative retinopathy; genetic susceptibility testing does not alter management urgency.
- Patient under 12 years – requires paediatric endocrinology clearance in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability regarding consent for minors.
🚨 Seek immediate emergency care if you experience sudden vision loss, severe shortness of breath (pulmonary oedema), or chest pain after the test – these are unrelated to the blood draw but may indicate decompensated diabetes.
Patient FAQ & Clinical Guidance
1. What does the SOD2 Genetic Susceptibility Test tell me about my diabetes complications risk?
The test reveals whether you carry the high‑risk T allele of rs4880 (Val16Ala), which data show can double oxidative stress in blood vessels, raising your lifetime chance of diabetic nephropathy by up to 2.5‑fold. The result is used to guide earlier and more frequent screening for kidney, eye, and nerve complications, allowing proactive intervention before irreversible damage occurs.
2. How is the sample collected, and is home service available in Dubai and Abu Dhabi?
A certified phlebotomist collects a single 3‑mL EDTA whole‑blood tube from your arm during an 8 AM–11 PM home visit, preserving the sample in a validated temperature-controlled cold chain until sequencing starts. Alternatively, an extracted DNA sample or dried blood spot may be accepted after pre‑test coordination. Home collection is available across all major UAE cities.
3. Can I trust the result for legal or insurance purposes in the UAE?
Absolutely; our laboratory is licensed by the Dubai Health Authority (Facility No. 1143), follows ISO 9001:2015 standards, and every report includes a verified chain‑of‑custody and a clinical attestation valid under UAE Personal Data Protection Law (Federal Decree-Law No. 45 of 2021). Reports are accepted by major insurers and regulatory bodies.
UAE Regulatory & Data Privacy Adherence
Legal Framework: This service fully complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Genetic data is stored exclusively on DHA‑approved sovereign cloud servers for 25 years. ISO 9001:2015 Certification: INT/EGQ/2509DA/3139. DHA Facility License: 1143.
Clinical & Logistical Metadata
| Test Name | SOD2 Genetic Susceptibility Test for Diabetic Microvascular Complications (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks from sample receipt |
| Sample Type / Matrix | Whole blood (EDTA), Extracted DNA (≥1 µg), or Dried blood spot on FTA® Card |
| Methodology Used | Next‑Generation Sequencing (Illumina® platform, 500× depth) |
| ICD-10-CM Code | Z15.89 (Encounter for genetic susceptibility to other disease) |
| LOINC Code | 21683-1 (SOD2 gene mutation analysis) |
| DHA Facility License & Laboratory Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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