Test Price
1,800 AED✅ Home Collection Available
Spinocerebellar Ataxia (SCA) Comprehensive Profile | 1,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
A comprehensive genetic test for spinocerebellar ataxia subtypes using PCR-based fragment analysis and STR genotyping, providing 99.9% diagnostic sensitivity. Sample collection is performed via VIP Mobile Phlebotomy with temperature-controlled cold-chain logistics, available daily from 8 AM to 11 PM. Post-result telephonic guidance is provided by a DHA-licensed consultant medical geneticist. Insurance verification available via WhatsApp.
Test Overview & Methodology
The Spinocerebellar Ataxia (SCA) Comprehensive Profile detects pathogenic trinucleotide repeat expansions and mutations in genes associated with SCA types 1, 2, 3, 6, 7, 8, 10, 12, 17, and DRPLA. Methodology includes multiplex PCR, high-resolution fragment analysis via capillary electrophoresis, and STR genotyping validated against reference materials. This approach delivers definitive genetic diagnosis for hereditary ataxias.
| Feature | Our Test (Prime) | Closest Alternative |
|---|---|---|
| Precision | Fragment analysis by capillary electrophoresis with proprietary size standards | Standard PCR + electrophoresis or limited repeat‑primed PCR |
| Methodology | Multiplex PCR + fluorescent STR genotyping; validated against reference materials | Low‑plex or single‑locus approaches |
| Speed & Service | 5‑7 business days TAT with tele‑report guidance | Often >10 days, report‑only |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I want to emphasize that this SCA profile is a powerful diagnostic adjunct. Positive findings confirm a specific genetic subtype, but results must always be interpreted alongside clinical presentation and family history. A negative result does not rule out all hereditary ataxias. Comprehensive post-test genetic counseling is essential for every patient.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Important Safety Advisory
Medication Precaution
Do not discontinue or modify any prescribed medication, including anti‑epileptics, immunosuppressants, or anticoagulants, without explicit instruction from your treating physician. Abrupt changes may trigger severe neurological or systemic complications.
Exclusion Criteria & Red Flags
Patient Suitability
- Inability to provide a 4 mL whole blood sample in a lavender‑top EDTA tube via standard venipuncture.
- Active hemolytic anemia or severe thrombocytopenia unless cleared by a hematologist.
- Recent hematopoietic stem cell transplant (chimerism invalidates DNA source).
- Emergency Red Flags: Sudden worsening of ataxia with dysphagia, vision loss, or altered consciousness → seek immediate ER care. Do not wait for test results.
Patient FAQ & Clinical Guidance
1. What exactly does the Spinocerebellar Ataxia (SCA) Comprehensive Profile detect?
This test identifies pathogenic trinucleotide repeat expansions and mutations in genes associated with SCA types 1, 2, 3, 6, 7, 8, 10, 12, 17, and DRPLA, providing a definitive genetic diagnosis when clinical ataxia is present. The panel uses PCR and high‑resolution fragment analysis to count the exact number of repeats and differentiate between normal, borderline, and full‑mutation alleles. This information helps your neurologist determine the specific ataxia subtype, predict prognosis, and guide family screening.
2. How is the test performed and what preparation is required?
A certified phlebotomist collects a 4 mL whole blood sample in a lavender‑top EDTA tube, shipped refrigerated (never frozen) to our ISO‑certified laboratory within 24 hours. No fasting or special preparation is needed. However, you must complete the mandatory Genomics Clinical Information Requisition Form with your treating physician’s details and clinical history. If you are on any blood‑thinning medication, please inform the collection team to apply extra hemostasis.
3. What does a positive result mean and what are the next steps?
A positive result indicates you have a pathogenic repeat expansion that confirms a specific SCA subtype, but the clinical course varies; immediate post‑genetic counseling is essential. You will receive a telephonic guidance session with our DHA‑licensed consultant medical geneticist to interpret the report in context of your symptoms and family history. A positive result does not always mean immediate disability, and many patients benefit from early neurological rehabilitation and targeted therapies. Your physician will also discuss the implications for at‑risk relatives.
UAE Regulatory & Data Privacy Adherence
Legal Compliance Framework
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): All genomic data processed and stored exclusively on encrypted servers within UAE territory.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Secure electronic health record and telemedicine standards are strictly followed.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Clinical testing safety and patient consent protocols adhere to this law.
- ISO 9001:2015 Certified Laboratory (Cert: INT/EGQ/2509DA/3139) — ensuring quality management from collection to report.
- DHA/MOHAP: All tests conducted under DHA Facility License No. 1143 with DHA‑registered specialists.
Clinical & Logistical Metadata
| Test Name | Spinocerebellar Ataxia (SCA) Comprehensive Profile |
| Price (AED) | 1,800 AED |
| Turnaround Time | 5–7 business days from sample receipt |
| Sample Type / Matrix | Peripheral whole blood – 4 mL in lavender-top EDTA tube (refrigerated transport) |
| Methodology Used | Multiplex PCR, fragment analysis by capillary electrophoresis, STR genotyping |
| ICD-10-CM Code | G11.9 |
| LOINC Code | 81320-0 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians