Test Price
2,800 AED✅ Home Collection Available
TMEM237 Gene Joubert Syndrome Type 14 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين TMEM237 لمتلازمة جوبيرت من النوع 14 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary & Clinical Guarantee
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with a specialist physician.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Overview
The TMEM237 Gene Joubert Syndrome Type 14 NGS Test detects disease-causing variants in the TMEM237 gene associated with Joubert syndrome, a rare ciliopathy marked by cerebellar vermis hypoplasia and neurological dysfunction. This comprehensive next-generation sequencing analysis offers a definitive molecular diagnosis, guiding early intervention and tailored management for affected individuals and at-risk family members across the UAE.
| Feature | Our TMEM237 NGS Test | Closest Alternative (Targeted Sanger) |
|---|---|---|
| Precision | Full gene coverage, CNV detection, >99.9% analytical sensitivity | Limited to known hot-spot mutations, missed large deletions |
| Methodology | NGS (Next-Generation Sequencing) with proprietary bioinformatics | Sanger sequencing of selected exons |
| Speed | 3–4 Weeks (wet-lab + analysis) | 4–6 Weeks (if multiple targets required) |
Physician Insight & Safety Protocol
“A positive TMEM237 variant is not a final verdict but a starting point for multidisciplinary care. I always emphasize that genotype-phenotype correlation and family studies are essential before making any major clinical decisions. Please involve your neurologist and clinical geneticist when interpreting these results.”
— Dr. PRABHAKAR REDDY, Consultant Neurologist (DHA License: 61713011)
⚠️ Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- This test is not for individuals without a clinical suspicion of Joubert syndrome or a known family history.
- Genetic counselling is mandatory prior to sample collection; patients who refuse counselling are excluded.
- If the patient exhibits acute neurological deterioration, seizure, or respiratory distress, seek emergency care immediately—do not wait for test results.
- Pediatric samples require parental consent as per UAE CDS Law 2026 (Minors).
Patient FAQ & Clinical Guidance
1. How accurate is the TMEM237 NGS test for Joubert syndrome, and can it detect all mutations?
Our NGS approach achieves over 99.9% analytical sensitivity and specificity, delivering a near-exhaustive screen of the entire TMEM237 coding region, including point mutations, small insertions/deletions, and copy number variants. While no can claim 100% coverage of every possible non-coding region, our protocol identifies the vast majority of clinically relevant variants, providing a reliable molecular diagnosis when interpreted alongside clinical and radiological findings.
يحقق فحص تسلسل الجيل التالي لدينا حساسية تحليلية تزيد عن 99.9% لتغطية كاملة لمنطقة ترميز جين TMEM237، بما في ذلك الطفرات النقطية والحذف والازدواج الصغير. لا يمكن لأي اختبار إحصاء جميع المتغيرات غير المشفرة، إلا أن منهجيتنا تحدد الغالبية العظمى من المتغيرات ذات الصلة سريريًا.
2. What is the sample requirement, and does the price include home collection?
We accept whole blood, extracted DNA, or a single drop of blood on an FTA card; the collection kit is provided during our ISO-certified cold-chain home visit, which is included in the 2800 AED package. The sample is transported under strict temperature control to our central laboratory, ensuring specimen integrity and uncompromised sequencing quality.
نقبل الدم الكامل أو الحمض النووي المستخلص أو قطرة دم واحدة على بطاقة FTA، وتُقدم خدمة السحب المنزلي المعقمة والمبردة ضمن السعر البالغ 2800 درهم. يُنقل العينة وفق معايير صارمة لضمان سلامتها واستقرارها حتى وصولها المختبر.
3. How will I receive my results, and who will explain them?
A detailed digital report is shared securely via our patient portal within 3 to 4 weeks, and a pre-scheduled telephonic consultation with a physician fluent in your language is provided at no additional cost to walk you through the clinical significance, inheritance pattern, and recommended follow-up steps. All data is handled in compliance with UAE PDPL, accessible only to authorized healthcare professionals.
يُرسل تقرير رقمي مفصل إلى حسابك الآمن خلال 3 إلى 4 أسابيع، مع استشارة هاتفية مجانية مع طبيب متخصص لشرح النتائج وأهميتها الوراثية وخطوات المتابعة، وفقًا لقانون حماية البيانات الشخصية الإماراتي.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians