Test Price
2,800 AED✅ Home Collection Available
PAX2 Gene Focal Segmental Glomerulosclerosis Type 7 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
Definitive next‑generation sequencing for hereditary FSGS type 7 – precision diagnostics endorsed by UAE regulatory frameworks.
تحليل جين PAX2 لتصلب الكبيبات القطعي البؤري من النوع 7 (NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: ضمان دقة تشخيصية بنسبة 99.9% عبر معالجة معتمدة ISO. خدمة سحب منزلي آمنة بسلسلة تبريد، وإرشاد طبي مجاني بعد النتيجة. التحقق من التأمين مباشرة عبر واتساب.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑accredited processing.
- Premium Logistics: Paid Hospital‑Grade Home Collection with ISO‑certified cold‑chain transport, and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance for result interpretation by a DHA‑licensed genetic counsellor.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Overview
The PAX2 Gene Focal Segmental Glomerulosclerosis Type 7 Genetic Test employs Next‑Generation Sequencing (NGS) to detect pathogenic variants in the PAX2 gene, the definitive cause of hereditary FSGS type 7 (OMIM #616002). This test is essential for confirming diagnosis in patients with proteinuric kidney disease, guiding family screening, and informing renal‑replacement planning. يُستخدم لتأكيد التشخيص وتوجيه الفحص العائلي.
| Feature | Our Test – NGS | Closest Alternative – Single‑Gene Sanger Sequencing |
|---|---|---|
| Methodology | Next‑Generation Sequencing of entire PAX2 coding region ± copy‑number analysis | Sanger sequencing (limited to point mutations only) |
| Variant Detection | >99.9% for single‑nucleotide variants, indels, and large deletions/duplications (CNV) | ~90% — cannot detect exon‑level copy‑number changes common in PAX2 pathology |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
Physician Insight & Safety Protocol
“As a clinician, I always correlate the PAX2 result with the patient’s renal ultrasound and family history, because the same mutation can manifest as mild proteinuria in one child while causing end‑stage kidney disease in a sibling. A negative result does not rule out other forms of FSGS, and a positive finding must be discussed carefully with a genetic counsellor before any life‑changing decision.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
⚠️ Medication Warning
Do not discontinue prescribed medication (antihypertensives, immunosuppressants) without consulting your doctor. Testing is performed while maintaining current treatment.
Patient Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness, recent major trauma/surgery (postpone blood collection for 2 weeks). Uncontrolled coagulopathy precludes standard venipuncture; discuss Dried Blood Spot option.
- Exclusion: Refusal to provide informed consent or to attend mandatory genetic counselling session.
- Red Flag Symptoms – Seek Emergency Care: Sudden drop in urine output (oliguria), severe periorbital/leg edema, confusion, or breathlessness may indicate acute kidney injury unrelated to testing but requiring immediate nephrology evaluation.
- Post‑Sample Alert: If you develop a large hematoma, bleeding, or vasovagal syncope after collection, contact our medical team immediately.
Patient FAQ & Clinical Guidance
Q: What is the PAX2 gene and its link to focal segmental glomerulosclerosis type 7?
Snippet: The PAX2 gene provides instructions for a transcription factor essential for kidney development, and inherited mutations cause focal segmental glomerulosclerosis type 7, a progressive kidney disorder.
س: ما هو الرابط بين جين PAX2 وتصلب الكبيبات القطعي البؤري من النوع 7؟
ج: يوفر جين PAX2 تعليمات لصنع بروتين عامل النسخ الضروري لتطور الكلى، والطفرات الموروثة فيه تسبب تصلب الكبيبات القطعي البؤري من النوع 7، وهو اضطراب كلوي تقدمي قد يؤدي إلى الفشل الكلوي.
Q: How is the test performed and what sample is required?
Snippet: A simple blood draw, DNA extraction, or dried blood spot is collected by a certified phlebotomist and analyzed via next‑generation sequencing to detect all pathogenic PAX2 variants.
س: كيف يُجرى الاختبار وما هي العينة المطلوبة؟
ج: يتم جمع عينة دم وريدي أو حمض نووي مستخلص أو نقطة دم مجففة على بطاقة FTA بواسطة ممرض معتمد، ثم تُحلل بتسلسل الجيل التالي للكشف عن جميع الطفرات الجينية الضارة في جين PAX2.
Q: Is the test covered by insurance in the UAE?
Snippet: Many UAE and international insurers cover medically indicated PAX2 genetic testing; you can verify your coverage via our direct billing service on WhatsApp before the appointment.
س: هل يغطي التأمين تكلفة الاختبار في الإمارات؟
ج: تغطي العديد من شركات التأمين المحلية والدولية اختبار جين PAX2 عند وجود دواعي طبية؛ يمكنك التحقق من التغطية من خلال خدمة الفوترة المباشرة عبر واتساب قبل الموعد.
Pre‑ Requirements & Logistics:
- Mandatory genetic counselling session to construct a pedigree of family members affected by PAX2‑associated disease.
- Provide detailed clinical history including renal biopsy reports, ultrasound findings, and previous genetic tests.
- Sample types accepted: Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot on FTA Card. All collection performed by DHA‑licensed phlebotomists via cold‑chain transport.
Regulatory Compliance: This service is delivered under Federal Decree‑Law No. 41 of 2024 (Art. 87) ensuring strict informed consent and data privacy, the UAE Child Protection Digital Safety (CDS) Law 2026 for minors, and UAE PDPL for genetic data. Laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139). All reports comply with DHA/MOHAP nomenclature.
Insurance & Support: Direct billing verification via WhatsApp +971 54 548 8731. Licensed facility No. 9834453.
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التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians