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Test Price

2,800 AED

✅ Home Collection Available

HNF1A Gene (MODY3) Genetic Test in UAE – 2800 AED – DHA Licensed

Executive Summary & Core Metrics

Executive Summary

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-Licensed Medical Geneticists.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The HNF1A Gene NGS Test screens the entire coding region of the hepatocyte nuclear factor-1 alpha gene using deep sequencing with ≥99.9% analytical sensitivity, empowering targeted treatment—many patients can switch from insulin to oral sulfonylureas.

Feature Our Test: HNF1A Full Gene NGS Closest Alternative: MODY Panel (Limited HNF1A)
MethodologyNGS (Illumina NovaSeq, 100% exon coverage)Sanger sequencing / targeted mutation panel
Diagnostic Yield>99% for HNF1A coding variants~85% (misses novel variants)
Turnaround Time3–4 Weeks4–6 Weeks
Clinical ActionabilityDirect sulfonylurea sensitivity guidanceMay require reflex testing
Price (AED)2800~2200

Physician Insight & Safety Protocols

“Understanding the genetic basis of your diabetes allows us to tailor therapy precisely. This test not only confirms MODY3 but also opens the door to personalised treatment plans, potentially reducing or eliminating insulin dependence. I strongly recommend discussing results with a medical geneticist to integrate genotype with your clinical history.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Do Not Alter Medication Without Medical Guidance

Do not discontinue prescribed insulin or oral hypoglycaemics without consulting your physician. This test guides long-term management; acute changes can be dangerous.

Exclusion Criteria & Safety Protocol

  • Exclusion: Inability to provide whole blood, extracted DNA, or FTA card sample.
  • Exclusion: Unwillingness to attend a mandatory pre-test genetic counselling session (pedigree drawing required).
  • Emergency Red Flags: If you experience new-onset severe hyperglycaemia (>300 mg/dL), ketonuria, or altered consciousness, seek emergency care immediately—do not wait for genetic results.
  • Minors: Genetic testing in minors requires documented parental/guardian consent and a paediatric endocrinologist's referral, in accordance with UAE regulations.

Patient FAQ & Clinical Guidance

1. What is the HNF1A MODY3 genetic test, and why do I need it?

This test provides definitive genetic confirmation of maturity-onset diabetes of the young type 3 by sequencing the HNF1A gene, enabling personalised treatment decisions.

2. How should I prepare, and what sample is required?

A mandatory pre-test genetic counselling session will map your family pedigree; afterwards, a simple blood draw, extracted DNA, or one drop on an FTA card is collected at home by our cold-chain phlebotomy team.

3. How accurate is this test, and when will I get results?

The test achieves greater than 99.9% diagnostic sensitivity for HNF1A variants using ISO-certified NGS, with results available in 3–4 weeks followed by specialist tele-consultation.

UAE Regulatory & Data Privacy Adherence

This genetic testing service operates under the regulatory framework of the Dubai Health Authority (DHA) and complies with:

  • Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all patient data handling.
  • Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for digital health information security.
  • Federal Decree-Law No. 4 of 2016 on Medical Liability governing clinical testing safety and patient consent.

All genetic data is encrypted and stored in UAE-based servers with strict access controls. Laboratory processes are ISO 9001:2015 certified.

Clinical & Logistical Metadata

Test Name HNF1A Gene (MODY3) Full Sequencing – NGS
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot
Methodology Used Next-Generation Sequencing (NGS) – Illumina NovaSeq 6000, 100% exon coverage
ICD-10-CM Code E11.8 (Other specified diabetes mellitus – MODY)
LOINC Code 21652-0 (HNF1A gene mutation analysis)
DHA Facility License & Laboratory Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE

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