Test Price
2,800 AED✅ Home Collection Available
SLC2A2 Gene Fanconi-Bickel Syndrome – Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل تسلسل جين SLC2A2 لمتلازمة فانكوني-بيكل بتقنية الجيل التالي في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – Diagnostic Confidence You Can Trust
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: Hospital-Grade Home Collection via ISO-Certified Cold-Chain Transport & VIP Mobile Phlebotomy (8 AM – 11 PM).
- ✓ Clinical Guidance: Telephonic Post-Test Clinical Correlation Session with a DHA-Licensed Physician to interpret your results.
- ✓ Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
الملخص التنفيذي – دقة تشخيصية يمكنكم الوثوق بها
نقدم تحليل التسلسل الجيني الكامل لجين SLC2A2 باستخدام تقنية الجيل التالي (NGS) المعتمدة وفق معايير الآيزو 9001:2015، مع حساسية تشخيصية تبلغ 99.9%. يشمل الفحص خدمة سحب منزلي معتمدة بنظام النقل المبرَد المعزول، وجلسة تفسير سريري هاتفية بعد صدور النتائج مع طبيب مرخص من هيئة الصحة بدبي. الامتثال الكامل للمرسوم بقانون اتحادي رقم 41 لسنة 2024 وقانون البيانات الصحية الشخصية الإماراتي.
Clinical Overview – SLC2A2 / Fanconi-Bickel Syndrome Genetic Testing
The SLC2A2 gene encodes GLUT2, the facilitative glucose and galactose transporter critical for hepatorenal glucose homeostasis and pancreatic beta-cell sensing. Pathogenic variants in SLC2A2 cause Fanconi-Bickel Syndrome (FBS; OMIM #227810), a rare autosomal recessive disorder characterized by hepatomegaly, proximal renal tubular dysfunction, fasting hypoglycemia, and postprandial hyperglycemia. This NGS-based test performs comprehensive sequencing of all coding exons and splice-site junctions of the SLC2A2 gene, enabling definitive molecular diagnosis, carrier screening, and informed clinical management for affected individuals and at-risk family members across the UAE. يوفر هذا التحليل الجيني الشامل تشخيصاً جزيئياً دقيقاً لمتلازمة فانكوني-بيكل، مما يمكّن الأطباء من وضع خطة علاجية موجهة تشمل الإرشاد الغذائي والدوائي للمرضى في دولة الإمارات.
| Feature | Our Test – NGS Comprehensive | Closest Alternative – Single-Gene Sanger |
|---|---|---|
| Technology | Next-Generation Sequencing (NGS) – Full Gene Coverage | Sanger Sequencing – Selected Exons Only |
| Diagnostic Sensitivity | 99.9% – All Coding Regions + Splice Sites | ~85-90% – Limited to Known Hotspot Regions |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Copy Number Variant Detection | Included – CNV Analysis via NGS Depth | Not Routinely Available |
| Sample Flexibility | Whole Blood / Extracted DNA / FTA Card | Whole Blood Only |
Physician Insight & Safety Protocol
Clinical Note from Dr. Prabhakar Reddy (DHA License: 61713011) — "Fanconi-Bickel Syndrome is a complex multisystem disorder requiring nuanced clinical correlation. A positive SLC2A2 result confirms the molecular diagnosis and empowers your treating physician to tailor dietary interventions, electrolyte supplementation, and long-term surveillance. Equally, a negative result does not exclude other glycogen storage disorders or renal tubular pathologies — please ensure your results are reviewed within the full context of your biochemical and clinical phenotype by a qualified clinical geneticist or pediatric endocrinologist."
⚠️ Medication Advisory: Do not discontinue any prescribed medication — including bicarbonate, phosphate, vitamin D, or dietary regimens — without consulting your treating physician. Genetic test results inform long-term management but do not replace acute clinical decision-making.
🛑 Safety Exclusion Criteria & Emergency Red Flags
Exclusion Criteria for Home Collection:
- Active febrile illness (temperature ≥ 38.5°C) — reschedule after recovery.
- Recent blood transfusion (within 4 weeks) — may interfere with germline DNA analysis.
- Known active coagulopathy or platelet count below 50,000/µL — requires hospital-based collection.
- Age under 6 months without prior pediatric clearance — mandatory hospital setting.
- Lack of valid Emirates ID or guardian consent (for minors under 18 per CDS Law 2026).
Emergency Red Flags — Seek Immediate Medical Attention:
- Severe fasting hypoglycemia (blood glucose < 50 mg/dL) with altered consciousness.
- Profound metabolic acidosis (pH < 7.2) with rapid breathing or confusion.
- Acute renal failure with oliguria or anuria.
- Pathological fractures due to severe hypophosphatemic rickets.
- Uncontrolled hypergalactosemia with vomiting and lethargy.
UAE Regulatory & Legal Compliance
Federal Decree-Law No. 41 of 2024 (Article 87): This genetic test is conducted in full compliance with the UAE's updated healthcare liability framework, ensuring patient rights, informed consent, and clinical data integrity at every stage of the diagnostic process.
CDS Law 2026 – Minors & Vulnerable Populations: All genetic testing on individuals under 18 years requires documented guardian consent and mandatory pre-test genetic counseling as mandated by UAE Communicable Diseases Surveillance Law 2026 provisions for genetic services involving minors.
UAE PDPL (Personal Data Protection Law): Your genomic data is classified as sensitive personal data under UAE PDPL. All SLC2A2 sequencing data is stored on encrypted, UAE-sovereign servers with strict access controls. Data is never shared with third parties without explicit written consent.
ISO 9001:2015 Certification: Our laboratory holds active ISO 9001:2015 accreditation (Certificate: INT/EGQ/2509DA/3139), affirming our quality management system meets international standards for diagnostic accuracy and patient safety.
DHA Facility License: 9834453 — Authorized by the Dubai Health Authority for advanced genetic and molecular diagnostic services.
Frequently Asked Questions – SLC2A2 Genetic Testing
Q1: What does the SLC2A2 genetic test diagnose, and how long until I receive my results?
Snippet Answer: The SLC2A2 Genetic Test definitively diagnoses Fanconi-Bickel Syndrome — a rare inherited disorder affecting glucose and galactose transport — by analyzing all coding regions of the SLC2A2 gene with 99.9% sensitivity, delivering comprehensive clinical-grade results within 3 to 4 weeks from sample receipt.
Fanconi-Bickel Syndrome (FBS) presents with a distinctive combination of hepatomegaly, proximal renal tubular dysfunction causing phosphate and bicarbonate wasting, fasting hypoglycemia, and postprandial hyperglycemia. This test identifies pathogenic single-nucleotide variants, small insertions/deletions, and copy number variations within SLC2A2, enabling precise molecular confirmation. Pre-test genetic counseling is mandatory to review your family history and construct a detailed pedigree chart — this ensures the most accurate interpretation of your results.
يقوم هذا التحليل بتشخيص متلازمة فانكوني-بيكل بشكل قاطع من خلال تحليل جميع مناطق الترميز في جين SLC2A2، مع نتائج دقيقة تصدر خلال 3 إلى 4 أسابيع.
Q2: What sample types are accepted, and can I do the test from home in Dubai or Abu Dhabi?
Snippet Answer: We accept whole blood, extracted DNA, or a single drop of blood on an FTA card for the SLC2A2 test, and our ISO-certified home collection team serves all seven Emirates — including Dubai, Abu Dhabi, Sharjah, and Ajman — from 8 AM to 11 PM daily with guaranteed cold-chain integrity.
Our VIP mobile phlebotomy service eliminates the need for clinic visits. A trained phlebotomist arrives at your location with full cold-chain transport equipment. For pediatric patients, we employ specialized pediatric collection techniques to minimize discomfort. FTA card collections are ideal for patients in remote areas or for families coordinating multi-member screening. All samples are transported to our DHA-licensed facility (License: 9834453) under continuous temperature monitoring, ensuring DNA stability throughout transit.
نقبل عينات الدم الكامل أو الحمض النووي المستخلص أو بقعة دم على بطاقة FTA، مع خدمة سحب منزلي في دبي وأبوظبي وجميع الإمارات حتى الساعة 11 مساءً.
Q3: Is this test covered by insurance in the UAE, and what genetic counseling support do you provide?
Snippet Answer: Many UAE insurance plans now cover medically indicated genetic testing including SLC2A2 sequencing — our team provides direct billing verification via WhatsApp at +971 54 548 8731 — and every test includes a mandatory pre-test genetic counseling session plus a post-test telephonic clinical correlation with a DHA-licensed physician.
Genetic counseling is not optional — it is a required component of this diagnostic pathway per DHA and UAE Federal guidelines. Our certified genetic counselors will help you construct a comprehensive three-generation pedigree, explain inheritance patterns (autosomal recessive for FBS), and discuss implications for siblings, future pregnancies, and extended family members. Post-test, you will receive a scheduled telephonic consultation with a clinical geneticist or pediatric endocrinologist who will interpret your results in the context of your personal and family clinical history. For direct insurance pre-authorization checks, message us on WhatsApp with your policy details.
تشمل الخدمة جلسة إرشاد وراثي قبل الفحص واستشارة هاتفية بعد النتائج مع طبيب مرخص من هيئة الصحة بدبي لتفسير النتائج سريرياً.
Specimen Requirements & Pre-Test Instructions
Accepted Sample Types:
- Whole Blood (EDTA Tube – 3 to 5 mL)
- Extracted DNA (≥ 1 µg, A260/A280 ratio 1.8–2.0)
- One Drop Blood on FTA Card (air-dried, properly labeled)
Pre-Test Requirements:
- Clinical history documentation including age of symptom onset, biochemical lab reports, and imaging findings.
- Mandatory genetic counseling session to construct a detailed pedigree chart of family members affected with or suspected of having Fanconi-Bickel Syndrome.
- Signed informed consent form (provided by our team prior to collection).
- Valid Emirates ID — for minors, guardian's Emirates ID plus guardianship documentation.
Drug & Supplement Avoidance (Pre-Sample):
- No specific drug restrictions required for germline DNA testing.
- If on chronic glucocorticoid therapy, note this on your requisition form — does not affect DNA quality but is clinically relevant for result interpretation.
- Recent intravenous glucose or galactose infusion should be documented for clinical correlation.
Turnaround Time: 3 to 4 Weeks | Price: 2,800 AED | CPT Code Equivalent: 81406
Referring Specialists & Clinical Intent
The SLC2A2 Fanconi-Bickel Syndrome NGS Test is indicated for patients referred by the following clinical specialists, each addressing a distinct diagnostic pathway within the hepatology-nephrology-endocrinology spectrum:
Clinical Geneticist
Primary Specialist — Molecular diagnosis, carrier screening, family cascade testing, and recurrence risk counseling for autosomal recessive FBS.
Pediatric Endocrinologist
Metabolic Specialist — Diagnostic workup for unexplained hypoglycemia, growth retardation, and dysglycemia patterns suggestive of GLUT2 dysfunction.
Pediatric Nephrologist
Renal Specialist — Evaluation of proximal renal tubular dysfunction, hypophosphatemic rickets, and Fanconi-type electrolyte wasting syndromes.
2026 Medical Coding & Classification
| Code Type | Code | Description |
|---|---|---|
| ICD-10-CM (Primary) | E74.09 | Other glycogen storage disease — Fanconi-Bickel Syndrome |
| ICD-10-CM (Secondary) | N25.89 | Other disorders resulting from impaired renal tubular function |
| ICD-10-CM (Screening) | Z13.228 | Encounter for screening for other metabolic disorders |
| LOINC | 101399-9 | SLC2A2 gene full sequence analysis – NGS Methodology |
| OMIM | #227810 | Fanconi-Bickel Syndrome (FBS) |
Ready to Schedule Your SLC2A2 Genetic?
Home Collection Available Across All Emirates — Results in 3 to 4 Weeks — DHA-Licensed Facility
Facility License: 9834453 | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139)
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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