Test Price
2,800 AEDโ Home Collection Available
SLC2A2 Gene Fanconi-Bickel Syndrome โ Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- โ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
- โ Premium Logistics: Hospital-Grade Home Collection via ISO-Certified Cold-Chain Transport & VIP Mobile Phlebotomy (8 AM โ 11 PM).
- โ Clinical Guidance: Telephonic Post-Test Clinical Correlation Session with a DHA-Licensed Physician to interpret your results.
- โ Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Our comprehensive SLC2A2 gene sequencing provides definitive molecular diagnosis for Fanconi-Bickel Syndrome with 99.9% sensitivity. Home collection is available daily from 8 AM to 11 PM across all Emirates under strict cold-chain management.
Test Overview & Methodology
The SLC2A2 gene encodes GLUT2, the facilitative glucose and galactose transporter critical for hepatorenal glucose homeostasis and pancreatic beta-cell sensing. Pathogenic variants in SLC2A2 cause Fanconi-Bickel Syndrome (FBS; OMIM #227810), a rare autosomal recessive disorder characterized by hepatomegaly, proximal renal tubular dysfunction, fasting hypoglycemia, and postprandial hyperglycemia. This NGS-based test performs comprehensive sequencing of all coding exons and splice-site junctions of the SLC2A2 gene, enabling definitive molecular diagnosis, carrier screening, and informed clinical management for affected individuals and at-risk family members across the UAE.
| Feature | Our Test โ NGS Comprehensive | Closest Alternative โ Single-Gene Sanger |
|---|---|---|
| Technology | Next-Generation Sequencing (NGS) โ Full Gene Coverage | Sanger Sequencing โ Selected Exons Only |
| Diagnostic Sensitivity | 99.9% โ All Coding Regions + Splice Sites | ~85-90% โ Limited to Known Hotspot Regions |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Copy Number Variant Detection | Included โ CNV Analysis via NGS Depth | Not Routinely Available |
| Sample Flexibility | Whole Blood / Extracted DNA / FTA Card | Whole Blood Only |
Physician Insight & Safety Protocols
Clinical Note from Dr. Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA License: 9294403) โ "Fanconi-Bickel Syndrome is a complex multisystem disorder requiring nuanced clinical correlation. A positive SLC2A2 result confirms the molecular diagnosis and empowers your treating physician to tailor dietary interventions, electrolyte supplementation, and long-term surveillance. Equally, a negative result does not exclude other glycogen storage disorders or renal tubular pathologies โ please ensure your results are reviewed within the full context of your biochemical and clinical phenotype by a qualified clinical geneticist or pediatric endocrinologist."
โ ๏ธ Medication Advisory: Do not discontinue any prescribed medication โ including bicarbonate, phosphate, vitamin D, or dietary regimens โ without consulting your treating physician. Genetic test results inform long-term management but do not replace acute clinical decision-making.
๐ Safety Exclusion Criteria & Emergency Red Flags
Exclusion Criteria for Home Collection:
- Active febrile illness (temperature โฅ 38.5ยฐC) โ reschedule after recovery.
- Recent blood transfusion (within 4 weeks) โ may interfere with germline DNA analysis.
- Known active coagulopathy or platelet count below 50,000/ยตL โ requires hospital-based collection.
- Age under 6 months without prior pediatric clearance โ mandatory hospital setting.
- Lack of valid Emirates ID or guardian consent (for minors under 18 per UAE Federal regulations).
Emergency Red Flags โ Seek Immediate Medical Attention:
- Severe fasting hypoglycemia (blood glucose < 50 mg/dL) with altered consciousness.
- Profound metabolic acidosis (pH < 7.2) with rapid breathing or confusion.
- Acute renal failure with oliguria or anuria.
- Pathological fractures due to severe hypophosphatemic rickets.
- Uncontrolled hypergalactosemia with vomiting and lethargy.
Patient FAQ & Clinical Guidance
1. What is the SLC2A2 genetic test and how long does it take?
Snippet Answer: The SLC2A2 Genetic Test definitively diagnoses Fanconi-Bickel Syndrome โ a rare inherited disorder affecting glucose and galactose transport โ by analyzing all coding regions of the SLC2A2 gene with 99.9% sensitivity, delivering comprehensive clinical-grade results within 3 to 4 weeks from sample receipt.
Fanconi-Bickel Syndrome (FBS) presents with a distinctive combination of hepatomegaly, proximal renal tubular dysfunction causing phosphate and bicarbonate wasting, fasting hypoglycemia, and postprandial hyperglycemia. This test identifies pathogenic single-nucleotide variants, small insertions/deletions, and copy number variations within SLC2A2, enabling precise molecular confirmation. Pre-test genetic counseling is mandatory to review your family history and construct a detailed pedigree chart โ this ensures the most accurate interpretation of your results.
2. What sample types are accepted and can I do the test from home in Dubai or Abu Dhabi?
Snippet Answer: We accept whole blood, extracted DNA, or a single drop of blood on an FTA card for the SLC2A2 test, and our ISO-certified home collection team serves all seven Emirates โ including Dubai, Abu Dhabi, Sharjah, and Ajman โ from 8 AM to 11 PM daily with guaranteed cold-chain integrity.
Our VIP mobile phlebotomy service eliminates the need for clinic visits. A trained phlebotomist arrives at your location with full cold-chain transport equipment. For pediatric patients, we employ specialized pediatric collection techniques to minimize discomfort. FTA card collections are ideal for patients in remote areas or for families coordinating multi-member screening. All samples are transported to our DHA-licensed facility (License: 1143) under continuous temperature monitoring, ensuring DNA stability throughout transit.
3. Is this test covered by insurance in the UAE and what genetic counseling support do you provide?
Snippet Answer: Many UAE insurance plans now cover medically indicated genetic testing including SLC2A2 sequencing โ our team provides direct billing verification via WhatsApp at +971 54 548 8731 โ and every test includes a mandatory pre-test genetic counseling session plus a post-test telephonic clinical correlation with a DHA-licensed physician.
Genetic counseling is not optional โ it is a required component of this diagnostic pathway per DHA and UAE Federal guidelines. Our certified genetic counselors will help you construct a comprehensive three-generation pedigree, explain inheritance patterns (autosomal recessive for FBS), and discuss implications for siblings, future pregnancies, and extended family members. Post-test, you will receive a scheduled telephonic consultation with a clinical geneticist or pediatric endocrinologist who will interpret your results in the context of your personal and family clinical history. For direct insurance pre-authorization checks, message us on WhatsApp with your policy details.
UAE Regulatory & Data Privacy Adherence
Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): Your genomic data is classified as sensitive personal data under UAE PDPL. All SLC2A2 sequencing data is stored on encrypted, UAE-sovereign servers with strict access controls. Data is never shared with third parties without explicit written consent.
Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: All electronic health data processing, including the secure transmission of genetic test results, complies fully with this law, ensuring interoperability and confidentiality of your health information.
Federal Decree-Law No. 4 of 2016 on Medical Liability: All clinical testing safety and patient consent protocols adhere to this law, guaranteeing your rights and safety throughout the diagnostic process.
ISO 9001:2015 Certification: Our laboratory holds active ISO 9001:2015 accreditation (Certificate: INT/EGQ/2509DA/3139), affirming our quality management system meets international standards for diagnostic accuracy and patient safety.
DHA Facility License: 1143 โ Authorized by the Dubai Health Authority for advanced genetic and molecular diagnostic services, operating from Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | SLC2A2 Gene Fanconi-Bickel Syndrome โ Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Gene Coverage |
| ICD-10-CM Code | E74.09 |
| LOINC Code | 101399-9 |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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