Test Price
2,800 AED✅ Home Collection Available
PKHD1 Gene Polycystic Kidney and Hepatic Disease Genetic Test in UAE | 2,800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
High Analytical Sensitivity: 99.9% via ISO‑certified next‑generation sequencing (NGS) workflow. Rapid Turnaround: 3–4 weeks from sample receipt. VIP Home Phlebotomy: Temperature‑controlled cold‑chain collection available daily 8 AM–11 PM. Insurance Verification: Direct pre‑approval via WhatsApp +971 54 548 8731. All results include telephonic genetic counseling.
Test Overview & Methodology
This targeted NGS assay interrogates all coding exons and flanking intronic regions of the PKHD1 gene. Bioinformatic analysis with Sanger confirmation ensures detection of single nucleotide variants, small insertions/deletions, and splice‑site mutations. No fasting is required; a detailed three‑generation pedigree and pre‑test genetic counseling are recommended for accurate interpretation.
| Feature | DNA Labs UAE – PKHD1 NGS Test | Standard Sanger Sequencing |
|---|---|---|
| Precision | 99.9% Analytical Sensitivity | ~95% |
| Methodology | Targeted NGS (LC‑MS/MS validated) | Sanger Sequencing |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403), states: “The PKHD1 NGS test delivers definitive molecular diagnosis for autosomal recessive polycystic kidney disease, but results must always be correlated with clinical, imaging, and family history. A negative report does not exclude the condition if strong clinical suspicion remains. Our center provides comprehensive pre‑ and post‑test genetic counseling to guide patients and families.”
Important Clinical Advisory
This genetic test is designed as a diagnostic aid, not a substitute for ongoing clinical management. Do not alter any prescribed therapy solely based on test results without consulting your nephrologist or hepatologist. The laboratory recommends referral to a medical geneticist for interpretation.
Exclusion Criteria & Red Flags
- Exclusion: Active febrile illness or acute kidney injury – defer testing until clinically stable.
- Exclusion: Inability to provide informed consent; minors require legal guardian consent per UAE Federal Law No. 2 of 2019.
- ER Red Flags: Sudden severe flank pain, hematuria, or signs of acute liver failure require immediate emergency evaluation, not elective genetic testing.
Patient FAQ & Clinical Guidance
1. What does a positive PKHD1 NGS result mean for my child’s kidney and liver health?
A positive result confirms autosomal recessive polycystic kidney disease (ARPKD) with variable hepatic fibrosis. Early nephrological and hepatological surveillance, along with family planning, can be initiated. Genetic counseling is provided to discuss implications for the patient and at‑risk relatives.
2. How long does it take to receive the PKHD1 genetic test report in Dubai?
The report is issued within 3 to 4 weeks from sample arrival, including bioinformatics analysis and clinical interpretation. Results are delivered electronically and via a secure patient portal.
3. Is the PKHD1 genetic test covered by insurance in the UAE?
Many UAE insurers reimburse medically indicated genetic testing. Contact our insurance team on WhatsApp +971 54 548 8731 with your insurance card for direct verification and pre‑authorization assistance.
UAE Regulatory & Data Privacy Adherence
This laboratory service complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data are encrypted, access‑controlled, and handled in accordance with ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). Clinical safety is governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. Results are disclosed only to the ordering physician and the patient after verified consent.
Clinical & Logistical Metadata
| Test Name | PKHD1 Gene Sequencing (Autosomal Recessive Polycystic Kidney Disease & Hepatic Fibrosis) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card (Dried Blood Spot) |
| Methodology Used | Targeted Next‑Generation Sequencing (NGS) with Sanger Confirmation |
| ICD‑10‑CM Code | Q61.19 |
| LOINC Code | 76430-0 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians