Test Price
2,800 AED✅ Home Collection Available
NPHP3 Gene Nephronophthisis Type 3 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Clinical Excellence & Patient Safety
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 certified NGS processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic post-test result interpretation by a DHA-licensed specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The NPHP3 gene NGS test provides a comprehensive genetic analysis to identify pathogenic variants associated with nephronophthisis type 3, a hereditary ciliopathy affecting the kidneys, liver, and endocrine system. This test is essential for confirming clinical diagnosis, guiding family screening, and informing personalized management plans.
| Feature | Our NPHP3 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% Sensitivity for single nucleotide variants, indels, and copy number changes | Limited to known exons; may miss deep intronic or large rearrangements |
| Method | Next‑Generation Sequencing (NGS) with advanced bioinformatics | Capillary Electrophoresis (Sanger) |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Coverage | Full gene – all exons, exon‑intron boundaries, and relevant non‑coding regions | Typically only a few exons, based on prior knowledge |
Physician Insight & Safety Protocols
Clinical Insight
“This test provides a crucial genetic confirmation for nephronophthisis type 3; however, results must always be correlated with clinical imaging, renal function tests, and liver enzymes. As a DHA‑licensed consultant in medical genetics, I strongly advise patients to review every result with their treating nephrologist or clinical geneticist before making any life‑altering decisions.”
— Dr. Lina Osama Zaki Quteineh, DHA Registration ID: 9294403
Patient Safety Exclusion Criteria & ER Red Flags
- Exclusion: Lack of a documented clinical indication or referral from a consultant nephrologist or clinical geneticist.
- Exclusion: Inability to provide informed consent (or legal guardian consent for minors per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Exclusion: Subjects requiring emergency dialysis – genetic testing is not a substitute for acute care.
- ER Red Flags: Sudden vision loss, severe hypertension (>180/120 mmHg), altered mental status, or signs of acute liver failure – proceed directly to the nearest DHA‑accredited emergency department.
Patient FAQ & Clinical Guidance
1. What does the NPHP3 gene test detect?
This advanced genetic test analyzes the NPHP3 gene to identify mutations linked to nephronophthisis type 3, a progressive kidney disorder. It targets pathogenic variants associated with ciliary dysfunction and renal fibrosis.
2. Who should consider this test?
Individuals with a family history of nephronophthisis, unexplained renal cysts, or liver fibrosis are candidates for NPHP3 genetic testing. It is also recommended for patients presenting with early-onset renal failure of unclear etiology.
3. How long do results take and how are they delivered?
Results are typically available in 3 to 4 weeks after sample collection, securely delivered via encrypted electronic report accessible through our patient portal.
UAE Regulatory & Data Privacy Adherence
All clinical genetic testing services at DNA Labs UAE are fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient data is encrypted in transit and at rest, and all sample handling follows strict ISO standards. Consent and medical liability adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | NPHP3 Gene Nephronophthisis Type 3 Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Peripheral whole blood (5 mL EDTA tube). VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM). |
| Methodology Used | Next-Generation Sequencing (NGS) with bioinformatic variant analysis |
| ICD-10-CM Code | Q61.11 |
| LOINC Code | 88615-4 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians