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Test Price

2,800 AED

✅ Home Collection Available

MTO1 Gene Combined Oxidative Phosphorylation Deficiency Type 10 (COXPD10) Genetic Test in UAE – 2,800 AED

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% diagnostic sensitivity for MTO1 coding region variants via ISO 15189 accredited next-generation sequencing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
  • Clinical Guidance: Post-test telephonic counselling by a DHA-licensed Consultant Medical Genetics.
  • Insurance: Direct billing verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The MTO1 Gene NGS test definitively diagnoses Combined Oxidative Phosphorylation Deficiency Type 10, a severe mitochondrial disorder, by sequencing the entire coding region of the MTO1 gene using next-generation sequencing technology. This test empowers UAE families with precise genetic information, enabling early clinical intervention and informed reproductive choices.

Feature Our Test (COXPD10 NGS) Closest Alternative (Whole Exome)
Precision 99.9% Analytical Sensitivity for MTO1 variants ~95% (broader scope, lower depth)
Method Targeted NGS (full gene sequencing) Whole Exome Sequencing
Turnaround 3–4 Weeks 6–8 Weeks

Physician Insight & Safety Protocols

“A positive MTO1 finding must always be contextualised within the full metabolic and neurological picture. Targeted NGS offers high-resolution data, yet treatment decisions require integration with clinical examination and biochemical markers. I counsel families to use this result as a gateway to multidisciplinary care, not as an isolated verdict.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Important Clinical Advisory

🚨 Do not discontinue prescribed medication without consulting your doctor. Genetic results complement but do not replace ongoing clinical care.

Exclusion Criteria & ER Red Flags

  • Exclusion: Recent blood transfusion (within 2 weeks), inability to provide informed consent, or acute febrile illness requiring hospitalisation.
  • ER Red Flag: Sudden intractable vomiting, extreme lethargy, seizures, or loss of consciousness — these may signal a metabolic crisis requiring immediate emergency care.

Patient FAQ & Clinical Guidance

1. What is the MTO1 gene test used for?

This NGS test detects pathogenic mutations in the MTO1 gene causing Combined Oxidative Phosphorylation Deficiency Type 10, a multisystem mitochondrial disease. It aids in confirming a clinical diagnosis, identifying carriers, and guiding family planning through precise genetic data.

2. How is the MTO1 genetic test performed?

A certified phlebotomist collects a simple blood sample at your home — no fasting or special preparation is required. DNA is extracted from whole blood and analysed using next-generation sequencing to read the entire MTO1 coding region.

3. What do the test results mean?

A positive result confirms COXPD10, enabling early metabolic intervention and comprehensive genetic counselling for family members. A negative result significantly reduces the likelihood of the disease but does not rule out other mitochondrial disorders.

UAE Regulatory & Data Privacy Adherence

All genetic testing procedures at DNA Labs UAE comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is encrypted, access-controlled, and never shared without explicit authorisation.

Clinical & Logistical Metadata

Test Name MTO1 Gene Combined Oxidative Phosphorylation Deficiency Type 10 (COXPD10) Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood (peripheral venipuncture)
Methodology Used Targeted Next-Generation Sequencing (NGS) – full MTO1 coding region
ICD-10-CM Code E88.49
LOINC Code 82939-0
DHA Facility License & Laboratory Address License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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