Test Price
2,800 AED✅ Home Collection Available
KANK1 Gene Cerebral Palsy (Spastic Quadriplegic) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- ✓Diagnostic Accuracy: 99.9% sensitivity for KANK1 coding regions and exon-intron boundaries via ISO 9001:2015 accredited next-generation sequencing.
- ✓Premium Logistics: VIP Mobile Phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- ✓Clinical Guidance: Post-test telephonic genetic counselling and result interpretation by a DHA-licensed consultant medical geneticist.
- ✓Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The KANK1 gene genetic test detects pathogenic variants associated with autosomal recessive spastic quadriplegic cerebral palsy type 2. This molecular diagnostic assay enables precise genetic confirmation, informs prognosis, and guides family planning decisions for affected individuals and their families. Next-generation sequencing technology provides comprehensive coverage of the KANK1 coding region, splice sites, and flanking intronic sequences with high analytical sensitivity.
| Feature | KANK1 NGS Assay | Single-Gene Sanger Sequencing |
|---|---|---|
| Analytical Sensitivity | >99.9% for coding regions and exon-intron boundaries | Approximately 98% limited to targeted exonic amplicons |
| Method | Next-generation sequencing with copy number variant detection | Sanger sequencing without CNV analysis |
| Turnaround Time | 14 to 28 calendar days | 28 to 42 calendar days |
Physician Insight & Safety Protocols
"A positive KANK1 variant must be interpreted within the full clinical context including neurological examination, neuroimaging findings, and detailed family history. Genetic results alone are never diagnostic in isolation; thorough clinical correlation is essential. Our multidisciplinary team provides comprehensive support throughout the entire diagnostic journey." – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
⚠ Medication Warning
Do not discontinue prescribed antispasmodic, anticonvulsant, or any other medication without consulting your treating physician. This genetic test does not replace ongoing neurological or pharmacological therapy.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to obtain written informed consent from legal guardian (mandatory for minors).
- Exclusion: Uncontrolled seizure disorder within 24 hours of blood draw due to elevated vasovagal risk.
- Exclusion: Known haematological malignancy that may interfere with DNA extraction and sequencing quality.
- 🚨 Emergency Red Flag: Sudden escalation of spasticity accompanied by respiratory distress — proceed to emergency department immediately.
- 🚨 Emergency Red Flag: New-onset status epilepticus or unexplained loss of consciousness.
- 🚨 Emergency Red Flag: Clinical signs suggestive of acute intracranial infection including fever, nuchal rigidity, or altered mental status.
Patient FAQ & Clinical Guidance
1. What is the KANK1 gene test and why is it recommended for my child?
The KANK1 NGS test identifies inherited mutations that cause spastic quadriplegic cerebral palsy type 2, enabling precise molecular diagnosis and early therapeutic planning. It is typically indicated when a child presents with severe spasticity, motor developmental delay, and a suggestive family history. Results are delivered within 14 to 28 calendar days from our DHA-licensed laboratory in Dubai Healthcare City.
2. How accurate is the NGS method and what preparation is required?
Our ISO-accredited NGS platform delivers a diagnostic sensitivity exceeding 99.9% for KANK1 coding and splice-site variants, including detection of copy number alterations. No special preparation such as fasting is needed. A simple blood sample of 2 to 3 mL whole blood or a dried blood spot on an FTA card is collected at your convenience via our temperature-controlled courier service.
3. How do I schedule the test and verify my insurance coverage?
Scheduling is straightforward: send a WhatsApp message to +971 54 548 8731 with your Emirates ID and insurance policy details. Our team confirms coverage within two business hours and arranges a same-day home phlebotomy visit. Direct billing is processed with most major UAE health insurers. A pre-test genetic counselling session is scheduled per DHA and MOHAP regulatory guidelines.
UAE Regulatory & Data Privacy Adherence
🛡️ Your Data Is Protected Under UAE Federal Law
All genetic data and personal health information are processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE maintains rigorous data encryption, access control, and audit trail protocols to safeguard your confidentiality.
Clinical & Logistical Metadata
| Test Name | KANK1 Gene Cerebral Palsy (Spastic Quadriplegic) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 14 to 28 calendar days |
| Sample Type / Matrix | Peripheral whole blood (2–3 mL) or dried blood spot on FTA card |
| Methodology Used | Next-Generation Sequencing (NGS) with copy number variant detection |
| ICD-10-CM Code | G80.0 |
| LOINC Code | 92822-6 |
| DHA Facility License & Address | License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE — DNA Labs UAE |
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