Test Price
2,800 AED✅ Home Collection Available
FLNA Gene (Frontometaphyseal Dysplasia) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available Daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation by a DHA-Licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
This NGS-based genetic test identifies pathogenic variants in the FLNA gene responsible for frontometaphyseal dysplasia, providing a definitive molecular diagnosis to guide early multidisciplinary intervention.
Test Overview & Methodology
The FLNA Gene Genetic Test utilizes Next-Generation Sequencing (NGS) to analyze all coding regions and flanking introns of the filamin A (FLNA) gene. This method offers superior sensitivity (99.9%) over conventional Sanger sequencing, detecting both known and novel pathogenic mutations linked to frontometaphyseal dysplasia, an X-linked dominant disorder affecting skeletal, neurological, and cardiac development.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision / Coverage | Full gene sequencing, all coding regions ± flanking introns | Targeted mutation or limited gene segments |
| Method | Next‑Generation Sequencing (Illumina™ platform) | Capillary electrophoresis (Sanger) |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Sensitivity | 99.9% | 95–98% for targeted sites |
| Price | 2,800 AED | 3,200+ AED (estimate) |
Physician Insight & Safety Protocols
“As a DHA‑licensed Consultant Medical Genetics, I stress that FLNA‑related frontometaphyseal dysplasia presents a wide clinical spectrum. A positive NGS result must always be correlated with detailed clinical and radiological assessments. Timely genetic diagnosis enables targeted surveillance for skeletal, neurological, and cardiac complications, improving long‑term patient outcomes.” – Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory and Safety Protocols
Do not alter or discontinue any prescribed medication without consulting your physician. The following safety measures ensure sample integrity and patient well-being:
- Sample must be collected in an EDTA tube (3–5 mL venous blood) or via buccal swab/DNA FTA card under sterile conditions.
- Transport temperature: 2–8 °C for blood; FTA cards must be completely dry before sealing.
- Pre-test genetic counselling and family pedigree chart are mandatory before sample collection.
- In case of active high fever, systemic infection, or inability to provide informed consent, the collection will be deferred.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inability to provide informed consent; active high fever or systemic infection on day of collection; patient non‑cooperation (risk of haemolysis).
- Potential ER Red Flags: Sudden severe headache, acute visual loss, new‑onset seizures, rapid neurological decline, suspected raised intracranial pressure – seek immediate medical attention.
- Sample Integrity: Blood must be drawn into EDTA tube; DNA FTA cards must be completely dry before sealing; transported at 2‑8 °C.
Patient FAQ & Clinical Guidance
1. What is the FLNA Gene NGS test and why is it ordered?
The FLNA Gene NGS test identifies pathogenic mutations in the FLNA gene, which causes frontometaphyseal dysplasia. It is ordered to confirm a clinical diagnosis, guide multidisciplinary referrals, and provide accurate recurrence risk counselling for family planning.
2. How is the sample collected and what are the pre‑test requirements?
A venous blood sample (3–5 mL in an EDTA tube) or a buccal swab/DNA FTA card is collected via a hospital‑grade home visit. Pre‑test genetic counselling and a detailed family pedigree chart are mandatory to ensure accurate interpretation of results.
3. What does a positive result mean and what are the next steps?
A positive result indicates a disease‑causing FLNA variant, confirming the diagnosis of frontometaphyseal dysplasia. Immediate referral to a neurologist, clinical geneticist, and orthopaedic specialist is recommended for comprehensive management and surveillance.
4. How long does the test take and when can I expect results?
The turnaround time is 3–4 weeks from sample receipt. You will receive a detailed molecular report with a clinical interpretation, followed by a telephonic consultation with our geneticist to discuss the findings and next steps.
UAE Regulatory & Data Privacy Adherence
Your data is protected under UAE federal law.
- Data Privacy: All personal health information is handled in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical Safety: Patient consent and clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Accreditation: DNA Labs UAE operates under DHA Facility License No. 1143 and follows ISO 15189 and ISO 9001:2015 standards for clinical laboratory quality.
Clinical & Logistical Metadata
| Test Name | FLNA Gene (Frontometaphyseal Dysplasia) Genetic Test – NGS |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Venous Blood (EDTA) or Buccal Swab / DNA FTA Card |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina™ Platform |
| ICD-10-CM Code | Q78.8 (Other specified osteochondrodysplasias) |
| LOINC Code | 48804-5 (FLNA gene mutation analysis) |
| DHA Facility License & Laboratory Address | DNA Labs UAE | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians