Test Price
2,800 AEDโ Home Collection Available
FBN2 Gene Congenital Contractural Arachnodactyly Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Accuracy: >99% analytical sensitivity via Next-Generation Sequencing (NGS) with ISO 9001:2015 certified processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Post-Test Support: Complimentary telephonic clinical interpretation by a Consultant Medical Genetics specialist.
- Insurance Facilitation: Direct billing verification via WhatsApp at +971 54 548 8731 (DHA/MOHAP compliant).
Test Overview & Methodology
The FBN2 Genetic Test identifies pathogenic variants in the FBN2 gene associated with congenital contractural arachnodactyly (Beals syndrome), a rare heritable connective tissue disorder. This advanced Next-Generation Sequencing (NGS) analysis provides comprehensive exon-level coverage, delivering results in 3โ4 weeks to guide early intervention and family planning.
| Feature | Our Test (Precision NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) โ full gene & flanking intronic regions | Sanger sequencing of select exons only |
| Turnaround Time | 3โ4 Weeks | 6โ8 Weeks |
| Diagnostic Yield | >99% analytical sensitivity | ~85% (misses deep intronic/copy-number variants) |
| Validation | ISO 9001:2015, DHA/MOHAP accredited, CAP-aligned | Basic CLIA; limited UAE accreditation |
| Home Collection | Included โ VIP Mobile Phlebotomy with cold-chain (8 AMโ11 PM) | Not provided |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
"A precise molecular diagnosis in congenital contractural arachnodactyly does more than confirm a clinical suspicionโit provides the family with a roadmap. Each FBN2 variant we identify is interpreted within the full context of echocardiographic findings, ophthalmologic assessment, and three-generation pedigree. I guide every family through the implications with clarity and compassion, ensuring they understand that genetics is one piece of a comprehensive care plan."
Advisory โ Medication Continuity
⚠️ Critical Medication Advisory
Continue all prescribed medications (including beta-blockers for aortic root protection and any cardiovascular therapy) unless explicitly directed by your treating physician. Abrupt discontinuation of cardiac or musculoskeletal medications may precipitate serious adverse events such as aortic dissection, arrhythmia, or joint instability. Always consult your specialist before making any changes.
Safety Exclusion & Emergency Indicators
⚠️ Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Active febrile illness, blood transfusion within the preceding 4 weeks (may compromise DNA extraction purity), or inability to provide a venous blood sample or adequate FTA card blood spots.
- Seek Emergency Care Immediately If You Experience: Sudden chest pain, severe palpitations, or unexplained shortness of breath; sudden visual disturbance or lens displacement; acute joint dislocation or severe limb pain. These symptoms may signal life-threatening complications of connective tissue disorders and warrant urgent hospital evaluation.
Patient FAQ & Clinical Guidance
1. What exactly does the FBN2 NGS test detect and how accurate is it?
The FBN2 Genetic Test analyses your DNA to detect mutations causing congenital contractural arachnodactyly (Beals syndrome) with over 99% analytical accuracy. It sequences all coding exons and adjacent splice sites of the FBN2 gene, including detection of single nucleotide variants and small insertions/deletions that are missed by older methods. This test is validated according to ISO 9001:2015 and CAP molecular standards, ensuring diagnostic-grade results you and your physician can trust for clinical decision-making.
2. How is the sample collected and when will I receive the results?
A certified phlebotomist visits your home for a painless blood draw or FTA card blood spot collection anytime from 8 AM to 11 PM. The sample is immediately placed in an ISO-certified cold chain and transported to our laboratory. Results are reported within 3 to 4 weeks, with an option for expedited telephonic preliminary findings in urgent cases. We accept venous whole blood, extracted DNA, or a single drop of blood on an FTA card, offering maximum flexibility for paediatric and adult patients.
3. Is the FBN2 genetic test covered by insurance in the UAE, and how can I confirm?
Many UAE insurers now cover NGS-based genetic tests for suspected hereditary connective tissue disorders when prescribed by a Dermatologist, Pediatrician, or Neonatologist. Our billing team will directly verify your policy coverage through WhatsApp at +971 54 548 8731 before sample collection, eliminating any surprise out-of-pocket costs. We handle all pre-authorisation paperwork in accordance with DHA regulations and applicable federal laws. For self-pay patients, the all-inclusive price is 2800 AED.
4. What clinical information will my physician receive with the results?
Your referring physician receives a comprehensive clinical report that includes variant classification per ACMG guidelines, zygosity, pathogenicity assessment, and clinical correlation recommendations. The report also suggests appropriate surveillance measures (echocardiography, ophthalmology referral) and family cascade screening options. A post-test telephonic consultation with our Consultant Medical Genetics is included to discuss implications and next steps.
UAE Regulatory & Data Privacy Adherence
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): Your genetic information is classified as sensitive personal data, encrypted, stored exclusively within UAE borders, and only accessible with your explicit consent. No data is shared without a court order except as expressly permitted for treatment continuity.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: All electronic health data transmissions, including genetic test orders and results, comply with mandated cybersecurity standards and audit trail requirements for complete data integrity.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Your consent for genetic testing is documented in accordance with medical liability provisions, ensuring you receive comprehensive pre-test counselling and understand the scope, limitations, and potential implications of results.
- ISO 9001:2015 Certification: Certificate INT/EGQ/2509DA/3139 guarantees systematic quality management across sample collection, testing, and reporting phases.
- Parental Consent Protocol: For minors, written consent from a parent or legal guardian is mandatory; results are disclosed only to authorised guardians as per UAE child protection statutes.
Clinical & Logistical Metadata
| Test Name | FBN2 Gene Congenital Contractural Arachnodactyly Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Gene & Flanking Intronic Regions |
| ICD-10-CM Code | Q87.4 |
| LOINC Code | 60436-5 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
For appointments or insurance verification, contact +971 54 548 8731 (WhatsApp / call). Home collection available daily 8 AM โ 11 PM. All services provided in accordance with DHA and MOHAP regulations.
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ISO Accredited
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All reports reviewed by DHA-Certified physicians