Test Price
2,800 AED✅ Home Collection Available
FBLIM1 Gene (Kindler Syndrome) Genetic Test – Next-Generation Sequencing in Dubai, UAE
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post-Test Clinical Guidance with a board-certified genetic counselor to interpret results.
Insurance: Direct Billing Verification via WhatsApp
+971 54 548 8731.
Test Overview & Methodology
The FBLIM1 Next-Generation Sequencing (NGS) Genetic Test provides exhaustive analysis of the entire FBLIM1 gene, capturing single nucleotide variants, indels, and deep intronic mutations with >99.9% diagnostic sensitivity for Kindler syndrome—a rare dermato-osteo-immunological disorder.
This test is the definitive genetic tool for dermatologists, immunologists, and clinical geneticists, enabling accurate diagnosis, prognosis, and multidisciplinary care planning.
| Feature | Our NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) – full gene coverage | Targeted single-exon Sanger sequencing |
| Gene Coverage | 100% coding exons ± 10 bp flanking intronic regions | Limited to selected exons (typically <80% coverage) |
| Diagnostic Sensitivity | >99.9% | ~95% (misses deep intronic and copy-number variants) |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Genetics, I emphasize that this NGS test provides definitive molecular confirmation of Kindler syndrome, but results must always be correlated with the clinical phenotype. A negative report does not exclude all atypical presentations or phenocopies; therefore, continued dermatological surveillance and multidisciplinary follow-up remain essential for optimal patient care.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Note
Do not discontinue any prescribed medication without consulting your treating physician. Genetic testing is diagnostic and does not substitute ongoing medical management. Results should be interpreted in conjunction with clinical findings and family history.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- Patients under 18 years of age without legal guardian consent and prior approval from the UAE Genetic Testing Committee.
- Pregnant women, unless medically indicated after thorough genetic counseling.
- Active skin infection, cellulitis, or open wounds at the intended venipuncture site.
ER Red Flags (Seek Immediate Care)
- Rapidly enlarging, non-healing skin ulcer or lesion suspicious for squamous cell carcinoma.
- Signs of systemic infection (fever, chills) accompanied by severe blistering or skin fragility.
- Acute vision changes or eye pain (ectropion, keratitis).
Patient FAQ & Clinical Guidance
1. What is the FBLIM1 Gene NGS Test?
The FBLIM1 Next-Generation Sequencing (NGS) Genetic Test is a high-precision diagnostic tool that detects mutations in the FBLIM1 gene causing Kindler syndrome, a rare inherited disorder characterized by skin fragility, photosensitivity, poikiloderma, and elevated risk of squamous cell carcinoma. This comprehensive gene analysis confirms the clinical diagnosis, guides surveillance protocols, and enables cascade testing in at‑risk family members.
2. How is the sample collected and what is the turnaround time?
A simple blood sample is collected by our DHA-licensed phlebotomist during a home visit, with temperature-controlled cold-chain transport ensuring DNA integrity. Turnaround time is 3 to 4 weeks from receipt of the specimen at our genomics facility.
3. Do I need a genetic counseling session before testing?
Pre‑genetic counseling is required to review your family history, draw a pedigree, and ensure fully informed consent before sample collection. This mandatory session, provided by our certified genetic counselors, helps interpret the implications of a positive, negative, or variant-of-uncertain-significance result.
UAE Regulatory & Data Privacy Adherence
Your personal and genetic data are protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical procedures comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory holds DHA facility license number 1143 and is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | FBLIM1 Gene (Kindler Syndrome) Next-Generation Sequencing |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (or extracted DNA / dried blood spot on FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene coverage including coding exons and flanking intronic regions |
| ICD-10-CM Code | Q82.8 (Other specified congenital malformations of skin – Kindler syndrome) |
| LOINC Code | 59025-7 (Gene mutations identified in Specimen by Sequencing) |
| DHA Facility License & Location | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians