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Test Price

2,800 AED

✅ Home Collection Available

C4orf26 Gene Amelogenesis Imperfecta Type 2A4 Genetic Test – 2,800 AED

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Laboratory.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
  • Clinical Guidance: Confidential Post-Test Telephonic Clinical Guidance with a DHA-licensed clinician.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This advanced NGS panel interrogates the entire coding region of the C4orf26 gene to diagnose Amelogenesis Imperfecta Type 2A4, a hereditary enamel defect. Our ISO 9001:2015–certified, DHA-licensed laboratory delivers a complete molecular report within 3–4 weeks.

Feature Our NGS Test Conventional Sanger Sequencing
Gene Coverage Full gene (all exons + splice sites) Limited to selected exons
Detection Power SNVs, indels & copy number variants (CNVs) Only small mutations; CNVs often missed
Turnaround Time 3–4 weeks 4–6 weeks
Accreditation ISO 9001:2015, DHA-Licensed Variable; often non‑ISO
Sample Types Whole blood, extracted DNA, dried blood spot (FTA card) Usually blood or buccal swab

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh | Consultant Medical Genetics (DHA: 9294403) shares: “Understanding the genetic basis of Amelogenesis Imperfecta is crucial for tailored dental and medical management. This NGS test provides definitive answers, but it must be complemented by a thorough clinical examination and family history assessment. Our team is dedicated to supporting you throughout the diagnostic journey.”

Advisory: Test Limitations & Medication Caution

  • This test is for diagnostic purposes only and does not replace ongoing medical or dental care.
  • Do not discontinue any prescribed medication without consulting your doctor.
  • Results should be interpreted in conjunction with clinical findings and family history.

Exclusion Criteria & Emergency Red Flags

  • Exclusion Criteria: Active systemic infection, recent blood transfusion (<4 weeks), inability to provide informed consent (guardian required for minors).
  • Emergency Red Flags: If you experience sudden severe dental pain, facial swelling, high fever, or signs of sepsis, seek immediate emergency medical attention—do not wait for genetic results.
  • Minors: Testing of minors requires parental consent. All genetic data is protected under UAE PDPL (Federal Decree-Law No. 45 of 2021) and Federal Law No. 2 of 2019 Concerning the Use of ICT in Health Fields.

Patient FAQ & Clinical Guidance

1. What is the C4orf26 gene amelogenesis imperfecta type 2A4 NGS test used for?

This NGS test detects disease‑causing mutations in the C4orf26 gene to confirm hereditary Amelogenesis Imperfecta Type 2A4 diagnosis. It analyses the complete gene sequence, including copy number variants, and is ordered by dermatologists, pediatric dentists, or clinical geneticists when a patient presents with thin, pitted, or discoloured enamel without other known syndromes. A positive result facilitates personalised treatment planning and genetic counselling for family members.

2. How is the sample collected and what is the turnaround time?

A simple blood draw, cheek swab, or dried blood spot (FTA card) is taken by a certified phlebotomist, and results are delivered in 3–4 weeks. Our VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection service operates daily from 8 AM to 11 PM. No special fasting is required, but a pre‑test genetic counselling session is mandatory to draw a family pedigree and obtain informed consent.

3. Is this test covered by UAE health insurance?

Many UAE insurers cover genetic testing when medically indicated; our team verifies direct billing eligibility via WhatsApp at +971 54 548 8731. We work with leading networks including Daman, Thiqa, and Neuron, and provide a detailed pre‑authorisation support letter citing ICD‑10 code K00.5 and Z31.430. Co‑payments and plan limits vary, so please contact us prior to sample collection to avoid out‑of‑pocket surprises.

UAE Regulatory & Data Privacy Adherence

Data Protection & Privacy: All genetic data is handled in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent for genetic testing follows UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.

Accreditation: ISO 9001:2015 Certified (Certificate No. INT/EGQ/2509DA/3139) | DHA Facility License No. 1143

Laboratory Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

Clinical & Logistical Metadata

Attribute Value
Test Name C4orf26 Gene Amelogenesis Imperfecta Type 2A4 Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 weeks
Sample Type / Matrix Whole blood, extracted DNA, dried blood spot (FTA card)
Methodology Used Next-Generation Sequencing (NGS) – Full gene sequencing including CNV detection
ICD-10-CM Code K00.5, Z31.430
LOINC Code 21636-6
DHA Facility License & Address License: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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All reports reviewed by DHA-Certified physicians