SRGAP2 Gene Neuronal Migration Disorder Genetic Test in UAE | 2800 AED | DHA Approved

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.

Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy. Available daily from 8 AM to 11 PM.

Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.

Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This test analyzes the SRGAP2 gene using Next Generation Sequencing (NGS) to detect variants linked to neuronal migration disorders—conditions causing brain malformations, epilepsy, and intellectual disability. Single-nucleotide variants and copy number variations (CNVs) are identified with high precision using the Illumina platform in an ISO 9001:2015 accredited laboratory.

Feature	Our (SRGAP2 NGS)	Closest Alternative
Precision	99.9% Sensitivity, Single-Nucleotide & CNV Detection	Whole Exome Sequencing (Broader, Lower Depth)
Methodology	NGS (Illumina Platform, ISO 9001:2015 Lab)	Sanger Sequencing (Limited to Known Hotspots)
Speed	3–4 Weeks (Expedited Reporting Available)	Often 6–8 Weeks

Physician Insight & Safety Protocols

“SRGAP2-related neuronal migration defects are a spectrum; not every variant is pathogenic. Correlation with clinical features and family history is essential. As a Consultant Medical Genetics, I emphasize that genetic results are only one piece of the diagnostic puzzle and must never replace clinical evaluation.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403).

Advisory Note

Medication Caution

Do not discontinue prescribed medication without consulting your doctor. Genetic findings do not automatically warrant changes in current treatment plans. Always discuss result implications with your healthcare provider.

Exclusion Criteria & Emergency Red Flags

Contraindications for Testing

A confirmed contraindication to blood draw (e.g., severe coagulopathy) – home collection will be adjusted to heel-stick capillary card method only after physician approval.
Patient or legal guardian unable to provide informed consent. Mandatory genetic counseling per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
Acute neurological decompensation (status epilepticus, new focal deficits) – prioritize emergency care, postpone elective testing.
If the patient is a minor without a parent or legal guardian present, sampling is legally prohibited.

Patient FAQ & Clinical Guidance

1. What does a positive SRGAP2 result mean for my child’s development?

A positive result indicates a gene variant that may disrupt normal brain cell migration, potentially causing cortical malformations or epilepsy, but severity varies widely. Genetic consultation is essential to interpret the result within the full clinical context.

2. How should I prepare for the blood draw or FTA card collection?

No fasting or special preparation is needed; a single venipuncture or finger-prick drop on a DNA-stabilizing FTA card suffices for NGS analysis. Our mobile phlebotomist will collect the sample at your home in a fully safe and controlled manner.

3. Are my genetic data protected under UAE law?

Yes, your genetic data is anonymized, encrypted, and handled per Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Strict access controls ensure confidentiality.

UAE Regulatory & Data Privacy Adherence

Compliance & Data Protection

This test and all associated processing comply with UAE federal laws, including Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and informed consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is licensed by DHA (License No. 1143) and operates under the highest standards of laboratory quality and patient confidentiality.

Clinical & Logistical Metadata

Test Name	SRGAP2 Gene Neuronal Migration Disorder Genetic Test (NGS)
Price (AED)	2,800
Turnaround Time	3–4 weeks (expedited options available)
Sample Type / Matrix	Peripheral whole blood (venous or capillary) or FTA card – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM to 11 PM.
Methodology Used	Next Generation Sequencing (Illumina, ISO 9001:2015)
ICD-10-CM Code	Q04.8 (Other specified congenital malformations of brain)
LOINC Code	81233-7 (Genetic analysis of a specific gene by NGS)
DHA Facility License & Laboratory Address	License No. 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE