Test Price
2,800 AEDโ Home Collection Available
MSRB3 Gene Autosomal Recessive Deafness Type 74 (DFNB74) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all Emirates.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation provided by DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
A targeted next-generation sequencing (NGS) test detecting MSRB3 gene mutations linked to autosomal recessive non-syndromic hearing loss DFNB74, providing gold-standard diagnostic clarity for Emirati families. The test analyses the entire coding region and adjacent splice sites of the MSRB3 gene, identifying point mutations, small insertions/deletions, and copy number variants.
| Feature | Our MSRB3 NGS Test | Standard Hearing Loss Panel |
|---|---|---|
| Precision | >99.9% sensitivity for MSRB3 coding region | Limited coverage, may miss rare variants |
| Methodology | NGS with bioinformatic depth >100x | Multiplex ligation-dependent probe amplification or Sanger |
| Turnaround Time | 3-4 Weeks | 4-6 Weeks |
Physician Insight & Safety Protocols
โThe MSRB3 gene test offers definitive genetic confirmation for families facing hereditary hearing loss. It enables precise counseling for cochlear implant candidacy and early intervention. Always correlate results with audiometry and ENT examination. Never discontinue prescribed medications, especially ototoxic drugs, without physician supervision.โ
โ Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory: Medication Caution
Do not stop any prescribed medication, particularly ototoxic drugs or ear drops, without consulting your doctor. Abrupt discontinuation may worsen underlying health conditions.
Exclusion Criteria & Emergency Red Flags
- Not suitable for individuals with active untreated ear infections or acute illnesses that may interfere with blood collection.
- This test is for genetic diagnosis only. If you experience sudden severe hearing loss, vertigo, or facial weakness, seek emergency ENT care immediately.
Patient FAQ & Clinical Guidance
1. What is the MSRB3 gene deafness test?
This NGS test finds MSRB3 gene variants causing autosomal recessive deafness DFNB74 with 99.9% diagnostic accuracy.
The test sequences the entire coding region and adjacent splice sites of the MSRB3 gene, detecting point mutations, small insertions/deletions, and copy number variants. It confirms a diagnosis of autosomal recessive deafness type 74, differentiates it from other genetic hearing losses, and aids in family counseling and early intervention planning. Results are interpreted by DHA-certified clinical geneticists.
2. Who should consider MSRB3 genetic testing?
Recommended for individuals with congenital bilateral sensorineural hearing loss, especially with family history of autosomal recessive inheritance or consanguinity.
Candidates include infants and children with hearing loss, as well as adults seeking carrier testing for family planning. Pre-test genetic counselling is mandatory to evaluate inheritance patterns and discuss implications. The test uses a simple blood draw.
3. How long does the MSRB3 genetic test take and what is the cost?
The NGS test takes 3-4 weeks after sample receipt and costs 2800 AED, including home phlebotomy across the UAE.
After sample receipt, the laboratory processes DNA, performs next-generation sequencing, bioinformatic analysis, and delivers a detailed clinical report within 3-4 weeks. The price covers all laboratory steps and reporting. Home phlebotomy is available daily 8 AMโ11 PM. Insurance direct billing can be verified via WhatsApp at +971545488731.
UAE Regulatory & Data Privacy Adherence
All genetic testing and handling of personal data comply with the following UAE federal laws:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ governing the collection, processing, and storage of genetic and health data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ ensuring secure digital transmission of test results and patient information.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ establishing the framework for clinical safety, informed consent, and patient rights during testing.
Patients have full rights to access, rectify, and request deletion of their data in accordance with PDPL provisions.
Clinical & Logistical Metadata
| Test Name | MSRB3 Gene Autosomal Recessive Deafness Type 74 (DFNB74) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3-4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) |
| Methodology Used | Targeted Next-Generation Sequencing (NGS) with >100x depth |
| ICD-10-CM Code | H90.5 |
| LOINC Code | 21756-8 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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