Test Price
950 AED✅ Home Collection Available
BCR-ABL1 Gene Load Test in UAE | 950 AED | Precision Molecular Diagnostics
Executive Summary & Core Metrics
- ✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✓Premium Logistics: Paid VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- ✓Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation from certified specialists.
- ✓Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The BCR‑ABL1 Gene Load Test quantifies the level of the abnormal gene produced by the Philadelphia chromosome (t(9;22)), the key driver in Chronic Myeloid Leukemia (CML) and a subset of Acute Lymphoblastic Leukemia (ALL). This quantitative analysis is critical for monitoring response to tyrosine kinase inhibitor therapy and detecting minimal residual disease (MRD).
| Feature | Our Premium Test | Closest Alternative |
|---|---|---|
| Methodology | Quantitative Real‑Time PCR (qPCR) on RNA, International Scale (IS) standardized | Standard PCR without IS conversion |
| Turnaround Time | 3 Working Days (written), Urgent phone alert within 24 hours | 5‑7 Days |
| Precision & Sensitivity | MR4.5 (deep molecular response) detection, ISO‑certified 99.9% sensitivity | Variable, often MR3.0 |
| Home Collection | Cold‑chain VIP phlebotomy, 8 AM‑11 PM | In‑centre only |
Physician Insight & Safety Protocols
“The BCR‑ABL1 International Scale (IS) provides a standardized yardstick for molecular response. A deep molecular response (MR4.5 or better) is the gateway to considering treatment-free remission, but this must be contextualized with the patient’s full hematological profile and adherence history. Serial monitoring at consistent intervals is paramount for clinical decision-making.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
⚠ Medication Advisory
Do not discontinue prescribed medication (especially tyrosine kinase inhibitors) without consulting your doctor. Abrupt cessation can cause rapid loss of molecular response and disease relapse.
Exclusion Criteria & Emergency Red Flags
- 🚫Exclusion: Not applicable for patients with no documented BCR‑ABL1‑positive leukaemia (CML/Ph+ ALL). Test requires a confirmed Philadelphia chromosome or BCR‑ABL1 rearrangement.
- 🚫Exclusion: Active severe infection; recent blood transfusion within 7 days may interfere with RNA quality.
- 🚨Emergency Red Flags (Go to ER immediately): Fever >38.3°C, uncontrolled bleeding, sudden severe bone pain, visual disturbances, or priapism in male patients.
- 🚨If you experience rapid weight loss, night sweats, or splenic discomfort, contact your haematologist before the scheduled test.
Patient FAQ & Clinical Guidance
1. What does the BCR‑ABL1 Gene Load number mean for my CML treatment response?
A result of ≤0.1% on the International Scale (MR3 or better) indicates a major molecular response, a key milestone in CML management. Lower levels, such as MR4.5 (0.0032%), signify a deep molecular response, often allowing treatment-free remission trials under strict haematologist supervision.
2. How do I prepare for this test and what documents are required?
You must sign the informed consent document and bring your complete clinical history confirming Philadelphia chromosome-positive leukemia diagnosis. Fasting is not required, but please disclose all medications, especially anticoagulants. Never stop your medication without consulting your doctor.
3. Why is molecular monitoring by qPCR (IS) the gold standard for CML?
Quantitative PCR on the International Scale ensures that your test results are comparable across laboratories worldwide, eliminating variability. This standardization is critical for accurately assessing treatment response, detecting early relapse, and making informed decisions about therapy adjustments.
UAE Regulatory & Data Privacy Adherence
Data Protection & Clinical Compliance
Your health data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ✓ISO 9001:2015 Certified Laboratory (Cert: INT/EGQ/2509DA/3139).
- ✓DHA Facility License No: 1143.
- ✓Strict confidentiality and secure electronic health records.
Clinical & Logistical Metadata
| Test Name | BCR-ABL1 Gene Load Test (International Scale) |
| Price (AED) | 950 AED |
| Turnaround Time | 3 Working Days (Written Report). Urgent Phone Alert within 24 hours. |
| Sample Type / Matrix | Whole Blood (EDTA tube) or Culture Cells |
| Methodology Used | Quantitative Real-Time PCR (qPCR) on RNA, International Scale (IS) Standardized |
| ICD-10-CM Code | C92.10 (CML, BCR/ABL-positive), C91.00 (Ph+ ALL) |
| LOINC Code | 18425-7 |
| DHA Facility License & Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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