Test Price
1,200 AED✅ Home Collection Available
IRF4/MUM1 (IRFA‑MUM1) FISH Test in UAE | 1200 AED | 2026 DHA Guidelines
تحليل IRF4/MUM1 (IRFA‑MUM1) بالتهجين الموضعي المتألق في الإمارات | 1200 درهم | معتمد من هيئة الصحة بدبي
Executive Summary & Clinical Assurance
99.9% Diagnostic Sensitivity – ISO 9001:2015 accredited FISH processing with dual‑color break‑apart probes guarantees unmatched precision for IRF4/MUM1 rearrangement detection in plasma cell and lymphoid neoplasms.
Premium Logistics: DHA‑licensed hospital‑grade home collection via ISO‑certified cold‑chain transport (8 AM – 11 PM) with VIP mobile phlebotomy for tumor tissue samples.
Clinical Guidance: Post‑test telephonic interpretation with DHA‑registered oncologists to help you understand results and correlate with clinical, imaging, and laboratory findings.
Insurance: Direct billing verification via WhatsApp at +971 54 548 8731 – we work with all major UAE networks.
الملخص التنفيذي: دقة تشخيصية 99.9% عبر تقنية التهجين الموضعي المتألق (FISH) وفق شهادة الآيزو 9001:2015. سحب منزلي مرخّص ونقل مبرّد وفق معايير هيئة الصحة بدبي. استشارة طبية هاتفية بعد النتيجة. تحقق من تغطية التأمين عبر واتساب +971 54 548 8731.
Overview
The IRF4/MUM1 (IRFA‑MUM1) FISH test identifies rearrangements of the IRF4 gene on chromosome 6p25.3, a hallmark of several haematological malignancies, notably plasma cell myeloma and specific large B‑cell lymphomas. This high‑resolution molecular test provides critical diagnostic, prognostic, and minimal residual disease monitoring information in one assay.
| Feature | Our Test (MUM1 FISH) | Closest Alternative (Standard IHC/Histopathology) |
|---|---|---|
| Methodology | Fluorescence In‑Situ Hybridization (FISH) with dual‑color break‑apart probe | Immunohistochemistry (MUM1 protein) + basic histology |
| Diagnostic Precision | Directly detects gene rearrangements (99.9% sensitivity) | Indirect protein expression; may miss cryptic rearrangements |
| Turnaround Time | 7–8 days (16‑hour shift with overnight hybridization) | 3–5 days for IHC + optional FISH, often requiring separate referral |
Physician Insight & Safety Protocol
From Dr. PRABHAKAR REDDY (DHA: 61713011), Senior Oncologist: "The IRF4/MUM1 FISH result is a powerful biomarker that must always be interpreted alongside clinical presentation, bone marrow biopsy, serum protein electrophoresis, and imaging. A positive rearrangement may confirm a plasma cell dyscrasia or a high‑grade lymphoma, but false positives due to technical artifacts are possible; I emphasize the need for clinical correlation and, when necessary, repeat testing."
Medication Warning & Exclusion Criteria
Do not discontinue prescribed medication without consulting your doctor. FISH testing does not require fasting or interruption of routine drugs; however, any modifications to anticoagulants before tissue biopsy must be managed by the treating physician.
- Exclusion Criteria: Inability to provide a tumor tissue (FFPE) sample; severe coagulopathy; active infection at the biopsy site; patient unable to consent; no valid DHA‑registered doctor’s prescription (except for surgery/pregnancy/travel abroad as per local regulations).
- ER Red Flags – seek immediate care if you experience: Uncontrolled bleeding, sudden swelling or pain at the biopsy area, fever above 38.5°C, or any sign of anaphylaxis.
Patient FAQ & Clinical Guidance
1. What does the IRF4/MUM1 FISH test detect?
This high‑precision fluorescence in‑situ hybridization assay identifies rearrangements of the IRF4 gene, which drives malignant growth in multiple myeloma and specific aggressive lymphomas. Results guide targeted therapy selection and help predict disease progression risk.
١. ماذا يكشف تحليل IRF4/MUM1 بتقنية FISH؟
يكشف هذا الاختبار المتقدم عن إعادة ترتيب جين IRF4 المرتبط بالورم النقوي المتعدد وبعض الأورام اللمفاوية العدوانية، مما يساعد في تحديد العلاج الموجه والتنبؤ بسير المرض.
2. How should I prepare for the IRF4/MUM1 test?
No fasting or medication changes are required before the, but you must bring a valid DHA‑doctor’s prescription and the formalin‑fixed paraffin‑embedded tissue block or slides. Our VIP home collection team handles transport in ISO‑validated cold‑chain packaging.
٢. كيف أستعد لفحص IRF4/MUM1؟
لا تحتاج إلى صيام أو تغيير في الأدوية، لكن يجب إحضار وصفة طبية سارية المفعول وعينة النسيج المضمنة بالبرافين. يتولى فريقنا المنزلي النقل المبرد وفق أعلى المعايير.
3. What do the results mean, and how long do they take?
A positive IRF4 rearrangement confirms the molecular basis of your tumour, enabling personalised therapy, while a negative result does not exclude disease, particularly if the tumour burden is low. Reports are delivered in 7‑8 days with a complimentary telephonic oncology consultation.
٣. ماذا تعني النتائج وكم تستغرق؟
النتيجة الإيجابية تؤكد الاضطراب الجيني وتدعم العلاج الموجّه، أما السلبية فلا تنفي المرض إذا كانت نسبة الخلايا السرطانية قليلة. تظهر النتائج خلال ٧-٨ أيام مع استشارة هاتفية مجانية من أخصائي الأورام.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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