Test Price
1,400 AED✅ Home Collection Available
FISH Prenatal Screening Panel (Chromosomes 13, 18, 21, X & Y) in UAE | 1400 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic post-test genetic counselling from a DHA-licensed Consultant Medical Genetics for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Regulatory Compliance: Full adherence to Federal Decree-Law No. 45 of 2021 (PDPL), Federal Law No. 2 of 2019 (ICT in Health Fields), and Federal Decree-Law No. 4 of 2016 (Medical Liability). All genetic data processed in-country with strict privacy safeguards.
Test Overview & Methodology
The FISH (Fluorescence In Situ Hybridization) Prenatal Screening Panel rapidly detects the most common chromosomal aneuploidies—trisomy 13, 18, 21 (Down syndrome), and sex chromosome abnormalities (X and Y)—directly on uncultured amniotic fluid cells. This targeted molecular cytogenetic method delivers results within four days, providing expectant parents with early diagnostic clarity and enabling informed clinical decision-making during high-risk pregnancies.
| Feature | Our FISH Panel (UAE) | Conventional Karyotype |
|---|---|---|
| Result Turnaround | 4 Days (Report by 4 pm) | 10–14 Days |
| Methodology | FISH (Interphase Nuclei Analysis) | Culture-dependent G-Banding |
| Diagnostic Scope | 5 critical aneuploidies (13,18,21,X,Y) | All chromosome number >5 Mb structural |
| Clinical Applicability | Rapid risk stratification in high-risk pregnancy | Confirmatory comprehensive analysis |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I interpret FISH results within the full clinical context of the pregnancy. A positive signal for trisomy 13, 18, 21, or sex chromosome aneuploidy provides a rapid diagnostic answer, yet a negative result does not exclude mosaic forms or structural rearrangements. Confirmatory microarray or karyotype analysis is often recommended to achieve complete resolution."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Pre-Procedure Advisory & Informed Consent
Amniocentesis for FISH analysis requires documented informed consent covering procedural risks, benefits, and alternatives. Any invasive diagnostic procedure carries a small risk of miscarriage (estimated <1 in 500 when performed under continuous ultrasound guidance by a qualified specialist). Patients experiencing cramping, vaginal bleeding, or fluid leakage after the procedure must seek emergency obstetric evaluation immediately. Do not alter any prescribed medication or prenatal supplement without consulting your managing obstetrician or maternal-fetal medicine specialist.
Exclusion Criteria & Emergency Red Flags
- Active vaginal bleeding or confirmed ruptured membranes before amniocentesis.
- Multiple gestation with chorionicity not clearly established.
- Maternal coagulation disorder or anticoagulant therapy not cleared by haematologist.
- Gestational age <15 weeks (amniocentesis not recommended).
- Red Flags after sample collection: fever >38°C, severe abdominal pain, or decreased fetal movements; proceed to nearest emergency room.
Patient FAQ & Clinical Guidance
1. What is the FISH prenatal screening panel and what does it detect?
Answer: The FISH prenatal panel directly identifies abnormal copy numbers of chromosomes 13, 18, 21, X, and Y in uncultured amniotic fluid cells, delivering results within 4 days for the most common aneuploidies associated with severe developmental disorders. It is a targeted diagnostic test, not a broad genomic screen.
2. How is the test performed and what are the risks?
Answer: A trained maternal-fetal medicine specialist extracts approximately 10 mL of amniotic fluid under continuous ultrasound guidance after 15 weeks of gestation. The overall procedural risk is less than 1 in 500 when performed by an experienced operator in a DHA-licensed facility. After extraction, the fluid is transported via secure medical courier to our ISO 9001:2015 accredited laboratory for FISH analysis.
3. When should this test be considered and how are results interpreted?
Answer: The panel is indicated for pregnancies with high-risk non-invasive prenatal testing (NIPT) results, advanced maternal age (≥35 years), or ultrasound markers suggestive of aneuploidy. A positive result should prompt formal genetic counselling before any pregnancy management decision. A negative result reduces but does not eliminate the possibility of a chromosomal abnormality, and confirmatory testing may be advised based on the full clinical picture.
UAE Regulatory & Data Privacy Adherence
This FISH Prenatal Screening Panel is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient genetic data is processed, stored, and transmitted within the UAE using encrypted infrastructure with strict access controls. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE operates under DHA Facility License Number 1143 and is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | FISH Prenatal Screening Panel (Chromosomes 13, 18, 21, X & Y) |
| Price (AED) | 1,400 AED |
| Turnaround Time | 4 Days (Report by 4 pm) |
| Sample Type / Matrix | Amniotic Fluid (Hospital Extraction Only) |
| Methodology Used | FISH – Interphase Nuclei Analysis on Uncultured Amniocytes |
| ICD-10-CM Code | Z36.0 (Encounter for antenatal screening for chromosomal anomalies) |
| LOINC Code | 82121-9 (Chromosomes 13, 18, 21, X, and Y interphase nuclei analysis) |
| DHA Facility License & Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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