Test Price
1,800 AED✅ Home Collection Available
FISH 1p/19q Codeletion Test in UAE | 1800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
Diagnostic Accuracy: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval for archival FFPE tissue blocks.
Clinical Guidance: Telephonic Post-Test Clinical Guidance with DHA-licensed medical genetics specialist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This FISH 1p/19q Codeletion Test is a targeted molecular cytogenetic analysis that detects the combined deletion of chromosome arms 1p and 19q in glioma tissue—critical for diagnosing oligodendroglioma and guiding personalized therapy. This chromosomal codeletion is a definitive diagnostic marker per WHO classification, directly influencing prognosis and chemotherapy response.
| Feature | Our Test: FISH 1p/19q Codeletion | Closest Alternative: NGS Panel / CMA |
|---|---|---|
| Precision | Single‑cell resolution, gold‑standard per WHO | Whole‑genome coverage but may miss low‑level mosaicism |
| Methodology | Fluorescence In‑Situ Hybridization (FISH) on FFPE | Next‑Generation Sequencing / Chromosomal Microarray |
| Turnaround Time | 7 working days | 10–14 working days |
| Price (AED) | 1,800 | 3,000+ |
| Clinical Actionability | Directly defines oligodendroglioma diagnosis and prognosis | Provides broader genomic profile but requires bioinformatics interpretation |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA License: 9294403 notes: “A positive 1p/19q codeletion result is a strong molecular hallmark of oligodendroglioma, conferring a more favorable prognosis and enhanced chemosensitivity. However, this genetic finding must always be integrated with histopathological and imaging data for a definitive diagnosis. Always consult your healthcare provider for personalized medical advice.”
Important Advisory: Never Self-Adjust Your Medication
Do not discontinue or alter any prescribed medication without consulting your doctor. This test result is for informational purposes and should not replace professional medical advice.
Exclusion Criteria & Emergency Red Flags
- FFPE tissue blocks with less than 10% viable tumor cells or extensive necrosis – insufficient for accurate FISH analysis; a new biopsy may be required.
- Sample not accompanied by a duly filled Chromosome & FISH Analysis Requisition Form (Form 17) – mandatory for processing.
- Emergency Red Flags: If you experience sudden severe headache, loss of consciousness, new‑onset seizures, or acute neurological deficits (e.g., vision loss, limb weakness), seek emergency medical attention immediately. These symptoms may indicate disease progression unrelated to test results.
Patient FAQ & Clinical Guidance
1. What is the 1p/19q codeletion test and why is it important for brain tumors?
The FISH 1p/19q codeletion test detects combined loss of chromosome arms 1p and 19q in glioma tissue, guiding diagnosis and treatment planning for oligodendroglioma patients. This genetic signature is a definitive diagnostic criterion per WHO classification, directly influencing prognosis and chemotherapy response. Without this test, oligodendrogliomas may be misclassified as astrocytomas, leading to suboptimal therapy.
2. How should I prepare for the test and what sample is required?
No patient preparation is needed; however, a formalin‑fixed paraffin‑embedded (FFPE) tissue block with at least 10% tumor content and a completed Chromosome & FISH Analysis Requisition Form (Form 17) is mandatory. The tissue block must be shipped via secure medical courier at room temperature to our laboratory.
3. How soon will I receive results, and will a doctor explain them?
Results are typically available within 7 working days, and a post‑test telephonic consultation with a DHA‑licensed medical genetics specialist is included to interpret the report. The report clearly states the presence or absence of 1p/19q codeletion and its clinical significance. Your treating physician can also schedule a dedicated interpretation session with our laboratory director.
UAE Regulatory & Data Privacy Adherence
Testing is performed under the Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability.
DHA Facility License No: 1143 | Laboratory performed at DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | FISH 1p/19q Codeletion Test |
| Price (AED) | 1,800 |
| Turnaround Time | 7 working days |
| Sample Type / Matrix | Formalin‑fixed paraffin‑embedded (FFPE) tissue block |
| Methodology Used | Fluorescence In Situ Hybridization (FISH) |
| ICD-10-CM Code | C71.9, Z15.09, C71.1 |
| LOINC Code | 82463-9 |
| DHA Facility License & Laboratory Address | DHA Facility License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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