Test Price
850 AED✅ Home Collection Available
FISH, 13q14.3 (D13S319) Deletion Test in UAE | 850 AED
Executive Summary & Core Metrics
Core Metrics at a Glance
Lab & Facility: DNA Labs UAE, DHA Licensed Facility No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Accuracy Guarantee: 99.9% Diagnostic Sensitivity for 13q14.3 deletions via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Turnaround Time: 4 Business Days (sample accepted daily before 4 PM).
Clinical Guidance: Telephonic post-test clinical guidance by a Consultant Medical Genetics to interpret results in the context of your complete hematologic profile.
Insurance & Billing: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This Fluorescence In-Situ Hybridization (FISH) test detects deletions in the 13q14.3 region, a critical prognostic marker in Multiple Myeloma. The D13S319 probe targets a locus commonly deleted in high-risk cases, directly informing risk stratification and treatment intensity. Unlike conventional karyotyping, FISH can analyze non-dividing cells, offering superior sensitivity and faster results.
| Feature | Our FISH 13q Test (DHA Licensed) | Conventional Karyotyping |
|---|---|---|
| Precision & Resolution | >99% sensitivity for clonal del(13q); detects non-dividing cells | ~30-40% sensitivity; requires dividing (mitotic) cells |
| Sample Types | Bone marrow aspirate or peripheral blood (Green Top-Heparin) | Primarily bone marrow aspirate |
| Turnaround Time | 4 Days | 7-14 Days |
Physician Insight & Safety Protocols
"The 13q14.3 deletion detected by FISH is a powerful independent prognosticator in multiple myeloma, but it is not a diagnostic standalone. This genetic finding must be interpreted alongside serum protein electrophoresis, immunofixation, and clinical history. A positive result stratifies patients into a high-risk group, guiding intensified therapy. The decision to start or adjust treatment is always multidisciplinary, never based on a single genomic event."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor.
- Anticoagulant & Antiplatelet Drugs: Avoid aspirin, clopidogrel, warfarin, or other anticoagulants/antiplatelet agents for the period specified by your physician prior to bone marrow collection. Herbal supplements such as Ginkgo biloba and high-dose Vitamin E must be stopped 7 days before the procedure.
- Post-Procedure Observation: Patients should be monitored for at least 1 hour after bone marrow aspiration to ensure no bleeding or hematoma formation.
Exclusion Criteria & Emergency Red Flags
Patient Exclusion Criteria
- Active Infection or Bleeding Diathesis: Bone marrow aspiration is contraindicated in the presence of active systemic infection or severe coagulopathy without prior correction.
- Pregnancy: Bone marrow sampling is not performed on pregnant patients due to positional discomfort and potential risk; alternative approaches will be discussed with your oncologist.
- Recent High-Dose Chemotherapy: Samples should not be collected within 24 hours of high-dose chemotherapy administration, as it may interfere with cell viability.
Post-Procedure Emergency Red Flags
- Excessive bleeding or large hematoma at the puncture site.
- Sudden severe pain, fever, chills, or signs of infection (e.g., redness, warmth).
- In such cases, proceed immediately to the nearest Emergency Department.
Patient FAQ & Clinical Guidance
1. What does a 13q14.3 deletion detected by FISH indicate for multiple myeloma prognosis?
A positive FISH result for 13q14.3 deletion places your multiple myeloma into a high-risk genetic subgroup. It means the plasma cells lack a tumor suppressor gene in this region, correlating with a more aggressive disease course. Your oncologist will use this information, combined with other lab findings, to recommend a tailored, intensive treatment plan in line with current clinical guidelines.
2. Why must this test be performed in a hospital setting?
The primary specimen for FISH analysis in multiple myeloma is bone marrow aspirate, which requires an invasive procedure performed only in a hospital or accredited clinic with appropriate sterile conditions and post-procedure monitoring. Peripheral blood may be used in specific cases, but collection for this test is still arranged through our hospital network to ensure proper handling and cold-chain transport. Home phlebotomy is not available for this test due to sample integrity and safety requirements.
3. How is the sample handled and what is the turnaround time?
After hospital extraction, the bone marrow or blood sample is collected in green top (sodium heparin) tubes and transported at 18-22°C by our ISO-certified courier service. Samples are accepted daily up to 4 PM. The turnaround time is 4 business days. A fully completed Chromosome & FISH Requisition Form (Form 17) is mandatory and will be guided by our team. Your results will be released with a detailed interpretive report followed by a telephonic consultation with a Consultant Medical Genetics.
UAE Regulatory & Data Privacy Adherence
Trust & Compliance Framework
Data Protection: Your genetic and clinical data are handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Clinical Safety: All invasive procedures and sample handling adhere to the standards set by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Accreditation: Our Dubai Healthcare City facility (DHA License No. 1143) is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139), ensuring the highest quality management and traceability throughout the testing process.
Clinical & Logistical Metadata
| Test Name | FISH, 13q14.3 (D13S319) Deletion Test |
| Price (AED) | 850 AED |
| Turnaround Time | 4 Business Days (sample accepted daily before 4 PM) |
| Sample Type / Matrix | Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. |
| Methodology Used | Fluorescence In-Situ Hybridization (FISH) with D13S319 probe set |
| ICD-10-CM Code | C90.0 |
| LOINC Code | 49595-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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