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Test Price

2,800 AED

โœ… Home Collection Available

FANCA Gene Fanconi Anemia Type A Genetic Test in UAE | 2800 AED | DHA Guidelines

Executive Summary & Core Metrics

Clinical Utility

Definitive genetic confirmation for suspected Fanconi anemia type A, enabling early intervention, precise family counseling, and informed reproductive planning. This test serves as the gold standard for diagnosing pathogenic variants in the FANCA gene.

Key Performance Indicators

  • ๐Ÿ”ฌ Accuracy: >99.9% diagnostic sensitivity and specificity via ISO 9001:2015 certified platform
  • ๐Ÿšš Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ€“ 11 PM)
  • ๐Ÿฉบ Post-Test Support: Complimentary telephonic genetic counseling session with DHA-licensed Consultant Medical Geneticist
  • ๐Ÿ’ณ Insurance Verification: Direct billing support via WhatsApp at +971 54 548 8731

Test Overview & Methodology

Comprehensive NGS Analysis of the FANCA Gene

The FANCA NGS test provides comprehensive analysis of all coding exons and flanking intronic regions of the FANCA gene using next-generation sequencing technology. This method achieves >99% analytical sensitivity for single nucleotide variants and small insertions/deletions, enabling the identification of pathogenic, likely pathogenic, and variants of uncertain significance (VUS). This represents the definitive diagnostic approach for Fanconi anemia complementation group type A, supporting diagnosis, carrier screening, and presymptomatic testing in at-risk family members.

Feature Our NGS FANCA Test Alternative Targeted Mutation Analysis
Methodology Next-Generation Sequencing (NGS) โ€“ full gene coverage Sanger sequencing of a single known familial variant
Variant Detection Scope SNVs, small indels, copy number variants (bioinformatically assessed) Only the pre-identified familial mutation
Turnaround Time 21โ€“28 business days (~3โ€“4 weeks) 10โ€“15 business days (~2โ€“3 weeks)
Clinical Application Diagnosis, carrier screening, VUS resolution, prenatal planning Confirmatory testing for known familial variant only
Regulatory Accreditation DHA / MOHAP accredited, ISO 9001:2015 certified laboratory May not satisfy comprehensive regulatory compliance frameworks

Physician Insight & Safety Protocols

โ€œReceiving a suspected diagnosis of Fanconi anemia brings profound uncertainty for families. This comprehensive NGS analysis of the FANCA gene delivers the definitive genetic evidence required to establish a precise diagnosis, determine carrier status, and guide informed reproductive decisions. It is essential, however, that all results are interpreted by a clinical geneticist within the full context of family history, clinical presentation, and hematological findings. A negative result does not rule out other complementation groups that may present with overlapping phenotypes.โ€

โ€” Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA License: 9294403

โš ๏ธ Medication Advisory

Do not discontinue, alter, or initiate any prescribed medication without direct consultation with your managing physician or specialist. Genetic test results are not a substitute for ongoing medical management.

Exclusion Criteria & Emergency Red Flags

  • Exclusion Criteria: Active severe infection, uncontrolled bleeding diathesis, or acute hematological crisis requiring immediate stabilization must be addressed prior to sample collection. This test is not indicated for somatic mutation analysis, minimal residual disease monitoring, or pharmacogenomic profiling.
  • Emergency Red Flags: Seek immediate emergency care if you experience sudden severe bruising, uncontrolled bleeding, signs of systemic infection (fever exceeding 38ยฐC), or if acute leukemia is diagnosed before test results are available. Genetic testing results never replace emergency clinical evaluation and treatment.

Patient FAQ & Clinical Guidance

1. What sample type is needed and when will I receive results?

Answer: This test requires 3โ€“5 mL whole blood collected in a standard EDTA tube (lavender-top), a dried blood spot on an FTA card, or previously extracted DNA from an accredited laboratory. Results are typically reported within 21 to 28 business days due to the extensive sequencing coverage, bioinformatics analysis, and clinical variant interpretation required.

2. Is this genetic test covered by UAE health insurance plans?

Answer: Most UAE health insurers provide coverage for medically necessary genetic testing when prior authorization is secured from the insurance provider. Our team performs direct billing verification via WhatsApp at +971 54 548 8731 before sample collection to confirm eligibility and minimize out-of-pocket expenses.

3. What clinical support is provided after receiving my results?

Answer: Every patient receives a complimentary telephonic post-test counseling session with our DHA-licensed Consultant Medical Geneticist. This session explains the clinical implications of your report, reviews variant classifications (pathogenic, likely pathogenic, VUS, or benign), and provides personalized guidance on next steps including hematology specialist referral, family cascade screening, and reproductive counseling if indicated.

4. How do I schedule a home phlebotomy appointment?

Answer: After test registration, our logistics team will coordinate a VIP Mobile Phlebotomy visit to your home or office within your preferred time window between 8 AM and 11 PM, including weekends. All samples are transported using ISO-certified temperature-controlled cold-chain couriers to ensure specimen integrity. Same-day booking is available subject to slot availability.

UAE Regulatory & Data Privacy Adherence

๐Ÿ“œ Regulatory Compliance Framework

All genetic testing services provided by DNA Labs UAE operate under strict adherence to UAE federal laws. Patient data processing and genomic information are fully protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety, informed consent, and medical liability are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and holds full DHA and MOHAP accreditation for genetic diagnostic services.

Clinical & Logistical Metadata

Test Name FANCA Gene Fanconi Anemia Type A NGS Genetic Test
Price (AED) 2,800 AED
Turnaround Time 21โ€“28 business days (~3โ€“4 weeks)
Sample Type / Matrix 3โ€“5 mL whole blood (EDTA tube), dried blood spot (FTA card), or previously extracted DNA
Methodology Used Next-Generation Sequencing (NGS) โ€“ full coding exons and flanking intronic regions with CNV assessment
ICD-10-CM Code D61.09 โ€“ Fanconi anemia (unspecified complementation group)
LOINC Code 21661-0 โ€“ Fanconi anemia gene mutation analysis
DHA Facility License & Laboratory Address License No. 1143 | DNA Labs UAE โ€“ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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All reports reviewed by DHA-Certified physicians