Test Price
2,800 AED✅ Home Collection Available
ERCC4 (FANCQ) Gene Genetic Test for Fanconi Anemia in Dubai, UAE | 2800 AED
Executive Summary & Core Metrics
Executive Summary
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-accredited next-generation sequencing.
- Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test genetic counseling and result interpretation by a Consultant Medical Genetics specialist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This ERCC4 (FANCQ) gene test uses next-generation sequencing to detect pathogenic variants causing Fanconi anemia complementation group Q, a rare DNA repair disorder. Early molecular diagnosis enables marrow failure surveillance, cancer predisposition monitoring, and informed family planning. The assay covers all coding exons and splice junctions with >99.9% analytical sensitivity and specificity.
| Feature | Our Test (Gold Standard) | Closest Alternative |
|---|---|---|
| Precision | >99.9% analytical sensitivity and specificity | Single-variant or panel with lower coverage depth |
| Method | Next-generation sequencing (full gene, all exons and splice sites) | Sanger sequencing (targeted regions only) |
| Speed | 3 to 4 weeks (comprehensive report with variant interpretation) | 4 to 6 weeks (often requires reflex testing) |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I emphasize that the ERCC4 gene test provides critical molecular confirmation for Fanconi anemia complementation group Q. This test enables precise genetic counseling, informs surveillance strategies for bone marrow failure and malignancy, and guides family planning decisions. The comprehensive NGS approach ensures high sensitivity for detecting pathogenic variants across the entire coding region. Results must always be correlated with clinical phenotype and family pedigree.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue, adjust, or initiate any prescribed medication without direct consultation with your treating physician. Genetic test results may inform but do not replace clinical judgment regarding therapeutic regimens.
Safety Exclusion & Emergency Red Flags
Exclusion Criteria:
- Inability to provide valid informed consent (minors without a legal guardian present).
- Active severe infection or blood transfusion within the past 14 days (sample may still be accepted with clinical caution).
- Uncontrolled bleeding diathesis contraindicating phlebotomy.
Emergency Red Flags (seek immediate medical attention):
- Sudden severe fatigue, pallor, or shortness of breath.
- Petechiae, easy bruising, or uncontrolled bleeding.
- Fever with signs of infection in an immunocompromised context.
Patient FAQ & Clinical Guidance
1. What is ERCC4 gene testing and why is it important for Fanconi anemia?
ERCC4 gene testing identifies pathogenic mutations in the FANCQ complementation group, enabling a definitive molecular diagnosis of Fanconi anemia. The ERCC4 gene encodes a DNA repair protein; biallelic mutations lead to bone marrow failure, congenital anomalies, and a markedly elevated risk of solid tumors. Our NGS panel covers all exons and splice sites, providing the precise genetic information needed to guide hematopoietic stem cell transplant timing, organ-specific cancer screening protocols, and reproductive counseling.
2. How is the sample collected and what is the turnaround time?
A simple blood draw or FTA card spot is collected at your home by a DHA-licensed phlebotomist through our VIP mobile phlebotomy service, available daily from 8 AM to 11 PM. The sample is transported in an ISO-certified temperature-controlled cold chain to our accredited laboratory in Dubai Healthcare City. Results are reported within 3 to 4 weeks from sample receipt. Prior to collection, a telephonic genetic counseling session is scheduled to review the pedigree and confirm clinical indication.
3. Is this test covered by insurance in the UAE?
We verify direct billing coverage with all major UAE insurers. Please send your Emirates ID and policy details via WhatsApp at +971 54 548 8731 for a coverage assessment. Eligibility depends on your individual plan and the clinical necessity documented by your referring physician. Our team provides pre-approval assistance and confirms financial responsibility before sample collection.
4. What happens after I receive my results?
A comprehensive clinical report is issued, and a telephonic follow-up consultation with our Consultant Medical Genetics specialist is scheduled to explain the findings, discuss clinical implications, and provide tailored recommendations for surveillance, family member testing, and reproductive options. You will receive a copy of the report and a summary letter for your referring hematologist or oncologist.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
This test is performed at DNA Labs UAE, a DHA-licensed facility (License No. 1143) located in Dubai Healthcare City, in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – governing the collection, processing, and storage of genetic and personal health data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating digital health records and telemedicine practices.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – ensuring clinical safety, informed consent, and professional accountability in diagnostic procedures.
All genetic data is encrypted, access-controlled, and retained in accordance with UAE federal data retention schedules. Results are shared only with the patient and designated healthcare providers upon explicit written consent.
Clinical & Logistical Metadata
| Test Name | ERCC4 (FANCQ) Gene Genetic Test for Fanconi Anemia |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks from sample receipt |
| Sample Type / Matrix | Peripheral whole blood or FTA card spot. VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM. |
| Methodology Used | Next-generation sequencing (NGS) – full gene coding exons and splice junctions |
| ICD-10-CM Code | D61.09 |
| LOINC Code | 21634-2 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians