EGFR MUTATIONAL ANALYSIS Test
Test Name: EGFR MUTATIONAL ANALYSIS Test
Components: PCR, Fragment Analysis, Sequencing
Price: 1640.0 AED
Sample Condition: Submit formalin fixed paraffin embedded block containing tumor tissue. Paraffin block must contain minimum 10% tumor cells. Ship at room temperature. Provide a copy of the Histopathology report. Duly filled NGS Test Requisition Formis mandatory.
Report Delivery: Sample Mon / Thu by 9 am; Report Fri / Tue
Test Type: Cancer
Doctor: Oncologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information: Provide a copy of the Histopathology report. Duly filled NGS Test Requisition Formis mandatory.
Overview
EGFR mutational analysis is a laboratory test that detects mutations in the EGFR gene. EGFR (epidermal growth factor receptor) is a protein involved in cell growth and division, and mutations in this gene can lead to the development of certain types of cancer, particularly lung cancer.
Procedure
The EGFR mutational analysis test is typically performed on a tumor sample obtained through a biopsy or surgery. The sample is analyzed in the laboratory to identify specific mutations in the EGFR gene. The most common mutations detected in this test are exon 19 deletions and the L858R point mutation in exon 21.
Importance of the Test
The results of the EGFR mutational analysis test can help guide treatment decisions for patients with lung cancer. Certain mutations in the EGFR gene are associated with increased sensitivity to targeted therapies, such as EGFR tyrosine kinase inhibitors (TKIs) like erlotinib, gefitinib, and osimertinib. These drugs specifically target the mutated EGFR protein and can help inhibit tumor growth.
Patients with EGFR mutations may be candidates for targeted therapy, while those without mutations may benefit more from other treatment options, such as chemotherapy or immunotherapy.
Conclusion
In conclusion, EGFR mutational analysis is a test that detects mutations in the EGFR gene and helps guide treatment decisions for patients with lung cancer.
Test Name | EGFR MUTATIONAL ANALYSIS Test |
---|---|
Components | |
Price | 1640.0 AED |
Sample Condition | Submit formalin fixed paraffin embedded block containing tumor tissue. Paraffin block must contain minimum 10% tumor cells. Ship at room temperature. Provide a copy of the Histopathology report. Duly filled NGS Test Requisition Formis mandatory. |
Report Delivery | Sample Mon / Thu by 9 am; Report Fri / Tue |
Method | PCR, Fragment Analysis, Sequencing |
Test type | Cancer |
Doctor | Oncologist |
Test Department: | MOLECULAR DIAGNOSTICS |
Pre Test Information | Provide a copy of the Histopathology report. Duly filled NGS Test Requisition Formis mandatory. |
Test Details |
EGFR mutational analysis is a laboratory test that detects mutations in the EGFR gene. EGFR (epidermal growth factor receptor) is a protein involved in cell growth and division, and mutations in this gene can lead to the development of certain types of cancer, particularly lung cancer. The EGFR mutational analysis test is typically performed on a tumor sample obtained through a biopsy or surgery. The sample is analyzed in the laboratory to identify specific mutations in the EGFR gene. The most common mutations detected in this test are exon 19 deletions and the L858R point mutation in exon 21. The results of the EGFR mutational analysis test can help guide treatment decisions for patients with lung cancer. Certain mutations in the EGFR gene are associated with increased sensitivity to targeted therapies, such as EGFR tyrosine kinase inhibitors (TKIs) like erlotinib, gefitinib, and osimertinib. These drugs specifically target the mutated EGFR protein and can help inhibit tumor growth. Patients with EGFR mutations may be candidates for targeted therapy, while those without mutations may benefit more from other treatment options, such as chemotherapy or immunotherapy. In conclusion, EGFR mutational analysis is a test that detects mutations in the EGFR gene and helps guide treatment decisions for patients with lung cancer. |