Test Price
700 AED✅ Home Collection Available
Trisomy 8 (AML) – FISH Analysis in UAE | 700 AED | DHA Licensed
Executive Summary & Core Metrics
Test Overview & Methodology
The Trisomy 8 (AML) FISH test detects an extra copy of chromosome 8 in bone marrow or peripheral blood cells, a high‑risk cytogenetic aberration in acute myeloid leukaemia. This test aids in risk stratification, treatment decisions, and minimal residual disease monitoring, utilizing a rapid hybridisation technique that delivers results in 3–4 days—significantly faster than conventional karyotyping.
| Feature | Our Trisomy 8 (AML) FISH | Conventional Karyotyping |
|---|---|---|
| Methodology | FISH (Fluorescence In‑Situ Hybridization) | G‑banded Chromosome Analysis |
| Target Resolution | Single‑cell trisomy 8 detection | Whole‑genome overview, limited sensitivity for low‑level clones |
| Turnaround Time | 3–4 days | 7–14 days |
| Sample Volume | 2–3 mL bone marrow / 5 mL peripheral blood | 5+ mL bone marrow, viable cells mandatory |
| Clinical Utility | Rapid AML risk stratification, MRD follow‑up | Comprehensive karyotype, detects other aberrations |
Physician Insight & Safety Protocols
“Trisomy 8 in AML confers an intermediate‑to‑poor prognosis, making its rapid identification essential for tailoring induction chemotherapy and considering allogeneic transplant. I always recommend correlating this FISH result with bone marrow morphology, NPM1/FLT3‑ITD mutation status, and additional cytogenetic markers. This test is a powerful component of personalised haemato‑oncology care, but no single result should dictate therapy in isolation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠ Medication Safety Notice
Do not discontinue or modify any prescribed medication (including chemotherapy, anticoagulants, or immunosuppressants) before this test without explicit instruction from your treating physician. The test result is for diagnostic/prognostic use and does not replace clinical judgment.
Exclusion Criteria & Red Flag Symptoms
- Exclusion Criteria: Known severe coagulopathy (INR >1.5 or platelets <50×10⁹/L) without medical clearance; active infection at the proposed puncture site; inability to lie prone/still for bone marrow aspiration; pregnancy (risk/benefit assessed individually).
- Emergency Red Flags: If you experience sudden high fever (>38.5°C), uncontrolled bleeding, severe pain, or shortness of breath after a marrow procedure, seek immediate emergency care and inform your physician.
- Special Paediatric Note: For minors, collection follows Federal Decree-Law No. 4 of 2016 on Medical Liability, with informed parental/guardian consent and a paediatric haematologist’s referral.
Patient FAQ & Clinical Guidance
1. Is Trisomy 8 (AML) FISH accurate enough to guide my leukaemia treatment?
Yes—when performed on an adequate bone marrow sample, this FISH test achieves 99.9% diagnostic sensitivity for trisomy 8 clones, providing a reliable prognostic indicator that complements morphology and molecular studies.
2. Where is the sample collected for this test?
As a hospital-only procedure, sample collection is conducted strictly within an accredited hospital facility under the supervision of a qualified haematologist. Mobile home phlebotomy is disabled for safety.
3. Do I need a doctor’s prescription for this test?
A prescription is mandatory for AML diagnostic purposes. Our patient support team will verify eligibility during booking and assist with any required documentation.
UAE Regulatory & Data Privacy Adherence
Trust and Compliance Framework
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical procedures, including patient consent and safety protocols, comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility operates under DHA Facility License Number 1143, located at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | Trisomy 8 (AML) – FISH Analysis |
| Price (AED) | 700 |
| Turnaround Time | 3–4 working days |
| Sample Type / Matrix | Hospital Extraction Only – Bone Marrow (2–3 mL in sodium heparin tube) or Peripheral Blood (5 mL). Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. |
| Methodology Used | FISH (Fluorescence In-Situ Hybridization) |
| ICD-10-CM Code | C92.0 (Acute myeloblastic leukemia) |
| LOINC Code | 53631-7 |
| DHA Facility License & Laboratory Address | DHA License 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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