Test Price
900 AED✅ Home Collection Available
Fluorescence In-Situ Hybridization (FISH) for Prenatal & Postnatal Diagnosis of Chromosomes 13 & 21 in UAE | 900 AED | 2026 DHA Guidelines
تحليل التهجين الموضعي المتألق للكروموسومات 13 و21 قبل وبعد الولادة في الإمارات | 900 درهم | معتمد من هيئة الصحة بدبي
📋 Executive Summary – Why Patients Trust Us
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139), ensuring reliable detection of trisomies 13 and 21.
- Premium Logistics: Paid Hospital-Grade Home Collection with ISO‑Certified Cold‑Chain Transport and VIP Mobile Phlebotomy, across Dubai, Abu Dhabi, and all Northern Emirates.
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation, directly aligned with DHA and MOHAP prenatal care pathways.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: اختبار دقيق ومعتمد من هيئة الصحة بدبي، يجمع بين الحساسية التشخيصية العالية والخدمة المنزلية المتميزة لنقل العينات مخبرياً بسلاسة تامة، مع دعم استشاري متكامل بعد النتائج.
Overview – Precision Cytogenetics for Expectant Families
Fluorescence In-Situ Hybridization (FISH) rapidly screens for numerical abnormalities of chromosomes 13 (Patau syndrome) and 21 (Down syndrome) in both prenatal and postnatal samples.
يكشف هذا الاختبار بسرعة عن اختلال الصبغيات 13 و21 في عينات السائل الأمنيوسي أو الزغابات المشيمية أو الدم بعد الولادة، مع نتائج خلال 10-12 يوماً.
| Feature | Our FISH Test (Premium) | Standard Karyotype (Alternative) |
|---|---|---|
| Target | Specific aneuploidy 13 & 21 | All chromosomes, structural anomalies |
| Methodology | Direct fluorescent probes on interphase nuclei | Cell culture, G‑banding analysis |
| Turnaround Time | 10–12 days | 14–21 days |
| Sample Types | Amniotic fluid, CVS, peripheral blood | Amniotic fluid, CVS, blood (with culture) |
Physician Insight & Safety Protocol
“As a gynecologist and maternal-fetal medicine expert, I understand how stressful prenatal testing can be. This FISH assay is a fast, reliable tool to ease anxiety when an ultrasound or biochemical screen suggests a possible trisomy. However, a positive result must always be confirmed by conventional karyotype and correlated with detailed clinical evaluation — no single test tells the whole story.” —Dr. PRABHAKAR REDDY, DHA License 61713011
⚠️ Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. No routine medication interferes with FISH analysis, but any change in prenatal supplements or anticoagulants should be managed by your treating physician.
🚨 Safety Exclusion Criteria & Red Flags
- Exclusion Criteria: Inability to provide informed consent (including minors without legal guardian consent as per UAE CDS Law 2026); current infection at the needle‑insertion site; uncorrected coagulopathy; suspected intra‑amniotic infection.
- ER Red Flags (post‑procedure): Sudden severe abdominal pain, heavy vaginal bleeding, fever ≥38.5°C, or clear fluid leakage — seek emergency medical care immediately.
- Data Privacy: All test results are protected under Federal Decree‑Law No. 41 of 2024 (Art. 87) and UAE PDPL; genetic data is anonymized and never shared without explicit consent.
Patient FAQ & Clinical Guidance
1. What does the FISH test for chromosomes 13 and 21 diagnose?
Snippet: This FISH test rapidly detects aneuploidies of chromosomes 13 and 21, aiding prenatal screening for Patau and Down syndromes.
The test uses fluorescent DNA probes that bind to specific regions of chromosomes 13 and 21 in uncultured cells. It provides a fast, accurate count of these chromosomes, indicating trisomy when three signals are present instead of two. This early information supports clinical decisions and genetic counseling.
خلاصة: يكشف اختبار FISH بسرعة عن اختلال الصبغيات 13 و21، مما يساعد في التشخيص قبل الولادة لمتلازمتي باتو وداون.
2. How is the sample collected for this FISH, and is it painful?
Snippet: Sample collection for prenatal FISH involves amniocentesis or chorionic villus sampling under ultrasound guidance, performed with mild discomfort not severe pain.
For prenatal diagnosis, a specialist obtains amniotic fluid or chorionic villi using a thin needle, while postnatal testing uses a simple blood draw. All invasive procedures are done under continuous ultrasound monitoring to ensure safety; most patients describe a brief cramp or pressure. Our mobile phlebotomy service ensures comfort and strict cold‑chain handling.
خلاصة: يتم جمع العينة بالسحب تحت توجيه الموجات فوق الصوتية، ويسبب انزعاجاً خفيفاً فقط، مع خدمة منزلية متكاملة.
3. How accurate is FISH for trisomy 21 compared to full chromosome analysis?
Snippet: FISH demonstrates over 99% sensitivity for trisomy 21, but it cannot detect structural chromosome rearrangements or mosaicism.
Clinical studies confirm FISH has near‑perfect sensitivity for the targeted aneuploidies; however, a negative result does not rule out other chromosomal abnormalities. A complete karyotype remains the gold standard and is often performed in parallel. Combining both provides the most comprehensive fetal genetic assessment.
خلاصة: تزيد حساسية FISH عن 99% للتثلث الصبغي 21، لكنه لا يكشف التغيرات البنيوية أو التزيق، لذا يُنصح بإجراء التحليل الكامل للصبغيات.
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