Test Price
900 AEDโ Home Collection Available
Peripheral Blood Karyotyping for Couples in UAE | 900 AED | Clinical Cytogenetic Analysis
Executive Summary & Core Metrics
Test Overview & Methodology
The Peripheral Blood Karyotyping (Couple) test is a cytogenetic analysis that examines chromosomes from blood cells to detect numerical or structural abnormalities causing infertility or recurrent pregnancy loss. This DHA-approved test provides definitive genetic insights for couples planning pregnancy or experiencing unexplained reproductive challenges. The analysis is performed using cell culture and conventional karyotyping with G-banding at 550-band resolution, enabling detection of balanced and unbalanced translocations, aneuploidies greater than 5-10 Mb, and other structural chromosomal rearrangements that may impact reproductive outcomes.
| Feature | Our Test (Peripheral Blood Karyotyping Couple) | Closest Alternative (Chromosomal Microarray) |
|---|---|---|
| Methodology | Cell Culture + Conventional Karyotyping (G-banding, 550-band resolution) | Array CGH/SNP (CMA), genome-wide |
| Precision | Detects balanced and unbalanced translocations, aneuploidies >5-10 Mb | Detects submicroscopic CNVs; misses balanced rearrangements |
| Turnaround | 10-12 Days | 14-21 Days |
| Cost (UAE) | 900 AED | Approx. 2500-3500 AED |
| Sample Type | Peripheral Blood (minimally invasive) | Blood (same) or tissue |
| Clinical Intention | Couple infertility / recurrent miscarriage workup | Primarily pediatric developmental disorders; may miss balanced translocations |
Physician Insight & Safety Protocols
"Karyotyping findings must be correlated with a comprehensive reproductive history and adjunct diagnostic evaluations. The absence of visible chromosomal abnormalities does not exclude all genetic contributions to infertility or pregnancy loss; advanced molecular testing may be indicated in specific clinical scenarios. Treatment decisions should never be based exclusively on this single assay." โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Important Pre-Test Disclosure
Certain pharmaceutical agents, particularly anticoagulants such as heparin, may interfere with cell culture viability and compromise karyotyping accuracy. Patients must disclose all current medications, including over-the-counter supplements and herbal preparations, to the attending phlebotomist prior to specimen collection. Do not alter or discontinue any prescribed medication regimen without explicit instruction from your treating physician.
Exclusion Criteria & Emergency Red Flags
- Active systemic infection or pyrexia exceeding 38ยฐC โ postpone collection until clinical resolution.
- Severe anemia or hemodynamic instability โ immediate emergency medical assessment is required.
- Known hematological malignancies may produce aberrant karyotypic results; prior oncology consultation is advised.
- Onset of sudden bleeding, intense pain, or syncope following phlebotomy warrants urgent presentation to the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What does peripheral blood karyotyping for couples detect?
A: This test identifies numerical and structural chromosomal anomalies, including balanced translocations, inversions, and aneuploidies that contribute to infertility or recurrent pregnancy loss. Both partners are screened simultaneously to assess heritable genetic risks that may affect reproductive outcomes.
2. Is a doctor's prescription mandatory for this test in the UAE?
A: Yes, a valid physician's prescription is legally required for cytogenetic testing under DHA regulation. Exemptions are limited to specific scenarios such as pregnancy confirmation, pre-surgical workup, or international travel clearance. Please confirm eligibility via WhatsApp at +971 54 548 8731.
3. How should I prepare for the blood collection procedure?
A: No fasting is required. Heparin-containing products must be discontinued 24 hours prior to phlebotomy. Inform the healthcare professional of any blood transfusion received within the preceding two weeks, as donor lymphocytes may affect karyotype interpretation.
4. When will results be available, and how are they delivered?
A: The standard turnaround time is 10-12 business days from sample receipt at our Dubai Healthcare City laboratory. Results are delivered via secure electronic report and accompanied by telephonic clinical guidance from a qualified genetics professional.
5. What does a normal karyotype result mean for our family planning?
A: A normal karyotype (46,XX for females and 46,XY for males at the 550-band resolution level) indicates no large-scale chromosomal abnormality was detected. However, this does not rule out submicroscopic genetic variants or single-gene disorders. Further molecular testing such as chromosomal microarray or next-generation sequencing may be recommended based on your clinical history.
UAE Regulatory & Data Privacy Adherence
Data Protection & Clinical Governance: This diagnostic service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic information is encrypted, access-restricted, and processed under explicit patient consent as mandated by Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE holds DHA Facility License No. 1143 and adheres to ISO 9001:2015 standards (Cert: INT/EGQ/2509DA/3139) for quality management across all laboratory operations.
Clinical & Logistical Metadata
| Test Name | Peripheral Blood Karyotyping for Couples |
| Price (AED) | 900 AED |
| Turnaround Time | 10-12 Business Days |
| Sample Type / Matrix | Peripheral Whole Blood โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Cell Culture + Conventional Karyotyping (G-banding, 550-band resolution) |
| ICD-10-CM Code | Z31.41, Z31.49 |
| LOINC Code | 53754-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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