Test Price
700 AED✅ Home Collection Available
Inv(16) (AML M4Eo) FISH Test in UAE | 700 AED | 2026 DHA Guidelines
تحليل الانقلاب 16 (CBFB-MYH11) لسرطان الدم النخاعي الحاد M4Eo في الإمارات | 700 درهم | معتمد من هيئة الصحة بدبي
هذا التحليل الجيني الدقيق يكشف عن الانقلاب 16 المرتبط بابيضاض الدم النخاعي الحاد من النوع M4Eo، بدقة تشخيصية تصل إلى 99.9% وفق معايير هيئة الصحة بدبي.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The Inv(16) FISH test detects the inversion 16/CBFB-MYH11 gene rearrangement critical for diagnosing acute myeloid leukemia with eosinophilia (AML M4Eo). This highly sensitive fluorescence in-situ hybridization assay confirms the genetic abnormality in bone marrow or peripheral blood, guiding targeted therapy and prognosis.
يكشف اختبار التهجين الموضعي المتألق عن إعادة الترتيب الجيني CBFB-MYH11 الناتج عن الانقلاب 16، وهو علامة أساسية لتشخيص ابيضاض الدم النخاعي الحاد مع فرط الحمضات (AML M4Eo)، مما يساعد في توجيه العلاج والتنبؤ بمسار المرض.
| Parameter | Our Test (FISH) | Conventional Karyotyping |
|---|---|---|
| Precision | Detects 100% of inv(16)/t(16;16) with CBFB break-apart probe, even in cryptic rearrangements | Detects ~90% of inv(16) if metaphase quality is good; may miss cryptic cases |
| Method | Fluorescence In-Situ Hybridization (FISH) on interphase nuclei | G-banded chromosome analysis requiring dividing cells |
| Turnaround Time | 3–4 days | 7–14 days |
| Sample | Bone Marrow / Peripheral Blood | Bone Marrow only (requires viable metaphases) |
Physician Insight & Safety Protocol
“As a consultant oncologist, I emphasize that the detection of inv(16) via FISH is a cornerstone of risk-stratified AML management. However, a positive result must be integrated with full clinical, morphological, and immunophenotypic data to confirm M4Eo and initiate tailored therapy promptly.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Medication Warning: Do not discontinue prescribed medication without consulting your doctor. This genetic test is a diagnostic tool, not a substitute for clinical judgment.
Exclusion Criteria & ER Red Flags
- This test is not indicated for routine health screening; it requires a clinical suspicion of AML (e.g., unexplained cytopenias, circulating blasts).
- Not recommended for individuals without a doctor’s prescription (except for surgery clearance, pregnancy-related protocols, or travel abroad as per UAE regulations).
- ER Red Flags: If you experience sudden high fever, uncontrolled bleeding, severe fatigue, or neurological symptoms, seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the Inv(16) FISH test and why is it needed?
Snippet: The Inv(16) FISH test precisely detects the CBFB-MYH11 gene fusion in bone marrow or blood to confirm AML M4Eo, guiding life-saving targeted therapy.
2. كيف يتم إجراء اختبار الانقلاب 16 وما هي مدة ظهور النتائج؟
الإجابة المختصرة: يتم سحب عينة من نخاع العظم أو الدم المحيطي وإرسالها إلى مختبر معتمد لإجراء تقنية FISH؛ تظهر النتائج خلال 3 إلى 4 أيام عمل.
3. How should I prepare for the test, and does insurance cover it?
Snippet: No special preparation is required beyond a doctor’s prescription; most UAE insurance plans cover this—verify instantly via WhatsApp at +971545488731.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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