Test Price
1,200 AED✅ Home Collection Available
FISH Amniotic Fluid Two‑Probe Panel (Trisomy 13 & 21) in UAE | 1200 AED | DHA Licensed Facility No. 1143
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited FISH processing on interphase nuclei, validated against full karyotype.
- Sampling Protocol: Hospital extraction only – sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Complimentary telephonic post‑test consultation for result interpretation and genetic counselling, arranged within 24 hours of report release.
- Insurance & Billing: Direct billing verification via WhatsApp at +971 54 548 8731 – we handle pre‑authorizations and insurance queries.
Test Overview & Methodology
The FISH (Fluorescence In‑Situ Hybridization) Two‑Probe Panel rapidly counts chromosome 13 and 21 signals in uncultured amniocytes, delivering a result within 4 days. This targeted prenatal test rules out aneuploidy with near‑perfect precision, supporting early clinical decisions. The methodology employs validated DNA probes specific to the centromeric regions of chromosomes 13 and 21, with a detection threshold of >99% sensitivity for trisomy.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative (cFISH) |
|---|---|---|
| Methodology | FISH on direct amniotic fluid, uncultured interphase nuclei, ISO 15189 validated probes | Standard FISH, often requires cultured cells, longer turnaround time |
| Turnaround Time | Report in 4 days (sample by 4 pm) | 5–7 days |
| Precision | 99.9% sensitivity, DHA‑compliant consent and identity verification | Variable probe sets, no local consent integration |
Physician Insight & Safety Protocols
“This FISH panel offers rapid reassurance for the most common viable autosomal trisomies. However, a normal result does not exclude other chromosomal anomalies; always correlate with complete karyotype and ultrasound findings. I am available to discuss any ambiguous result before you act.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Safety Notice
Medication Warning
Do not discontinue prescribed medications or alter pregnancy management solely on the basis of this test. Always consult your obstetrician or a maternal‑fetal medicine specialist.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Gestational age <15 weeks (risk of sampling error); maternal anticoagulation in the last 24 hours without clearance; known anhydramnios.
- ER Red Flags post‑amniocentesis: Heavy vaginal bleeding, gush of fluid (ruptured membranes), fever >38°C, severe cramping unrelieved by rest. Proceed to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. How accurate is the FISH amniotic fluid test for Trisomy 21?
This test demonstrates over 99.9% diagnostic sensitivity for Trisomy 21 when performed on an adequate sample, providing near‑certain detection of the most common aneuploidy. A negative result does not guarantee a normal karyotype; full chromosomal analysis is recommended.
2. Can I have the amniocentesis performed outside a hospital?
No. Amniocentesis is an invasive procedure that must be performed by a qualified maternal‑fetal medicine specialist within an accredited hospital setting to ensure patient safety and sample integrity. Home collection is not available for this test.
3. What happens if the result is positive?
A positive result should be confirmed by full karyotype and genetic counselling. Our team will arrange an urgent telehealth consultation with a consultant medical geneticist within 24 hours of report release to discuss implications and next steps.
UAE Regulatory & Data Privacy Adherence
All genetic testing and data handling comply with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. Results are released only after identity‑verified authorization.
Clinical & Logistical Metadata
| Test Name | FISH Amniotic Fluid Two‑Probe Panel (Trisomy 13 & 21) |
| Price (AED) | 1,200 |
| Turnaround Time | 4 working days (sample by 4 pm) |
| Sample Type / Matrix | Amniotic fluid (hospital extraction only) |
| Methodology Used | Fluorescence In‑Situ Hybridization (FISH) on interphase nuclei |
| ICD-10-CM Code | Q90.9, Q91.7 |
| LOINC Code | 33778-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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