Test Price
2,000 AED✅ Home Collection Available
Chromosome Interphase Profiling for Products of Conception (POC) Test in UAE | 2,000 AED | DNA Labs UAE
Executive Summary & Core Metrics
Diagnostic Accuracy: >99.9% sensitivity for targeted aneuploidy detection (chromosomes 13, 18, 21, X, Y) via ISO 9001:2015 accredited FISH methodology.
Specimen Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. Temperature-controlled courier transport is arranged by DNA Labs UAE.
Clinical Guidance: Post-result telephonic consultation with a Consultant Medical Geneticist to discuss recurrence risk and future prenatal planning.
Insurance & Billing: Direct billing verification available via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Chromosome Interphase Profiling using Fluorescence In-Situ Hybridization (FISH) on products of conception (POC) provides rapid, definitive detection of numerical chromosomal abnormalities (aneuploidies) in fetal tissue following miscarriage. The assay targets chromosomes 13, 18, 21, X, and Y — the five most clinically significant aneuploidies implicated in early pregnancy loss — and delivers results within 7 working days, enabling informed recurrence risk assessment and personalized future pregnancy management.
Comparative Test Performance
| Feature | Our Test (FISH Interphase) | Conventional Karyotype |
|---|---|---|
| Precision & Scope | Targeted aneuploidy detection (13, 18, 21, X, Y) with >99% diagnostic accuracy; unaffected by culture failure | Genome‑wide analysis but lower sensitivity for low‑level mosaicism; requires successful cell culture (15–30% failure rate in POC) |
| Methodology | Fluorescence In‑Situ Hybridization (FISH) on uncultured interphase nuclei | G‑banded karyotyping after tissue culture (7–14 days culture time) |
| Turnaround Time | 7 Working Days | 14–21 Working Days |
Physician Insight & Safety Protocols
“Each miscarriage carries a unique emotional and clinical weight. This FISH-based interphase profiling delivers rapid, actionable answers about chromosomal causes, allowing families to move forward with genetic clarity. Interpretation must always be integrated with the full obstetric and clinical history, and post-test genetic counseling is strongly recommended to contextualize recurrence risks and explore reproductive options.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Protocol
Critical Pre-Test Advisory
Do not discontinue any prescribed medication without consulting your referring physician. This test requires a minimum of 2 mg of fresh placental or fetal tissue collected under sterile conditions during miscarriage management. The specimen must be placed immediately in sterile normal saline or 10% neutral-buffered formalin and transported under refrigerated conditions (2–8°C). Freezing the specimen will cause cellular lysis and render the test invalid.
Exclusion Criteria & Emergency Indicators
- Exclusion Criteria: Insufficient tissue mass (<2 mg), improperly fixed or previously frozen specimens, tissue stored in formalin for more than 48 hours without refrigeration, or absence of a completed Chromosome & FISH Analysis Requisition Form (Form 17).
- Emergency Red Flags: In the post-miscarriage period, seek immediate emergency care if you experience severe abdominal pain, heavy vaginal bleeding (soaking more than 2 pads per hour), fever exceeding 38°C, chills, or foul‑smelling discharge — these signs may indicate retained tissue, infection, or incomplete evacuation requiring urgent gynecological assessment.
Patient FAQ & Clinical Guidance
1. What is chromosome interphase profiling for products of conception?
It is a FISH-based molecular genetic test that rapidly screens placental or fetal tissue for the most common numerical chromosomal abnormalities — aneuploidies of chromosomes 13, 18, 21, X, and Y — which together account for more than 60% of first-trimester miscarriages. Results are typically reported within 7 working days and provide a definitive genetic explanation for the pregnancy loss.
2. How should I prepare, and what type of sample is needed?
No dietary fasting or medication adjustment is required. The sample — a small fragment of placental or fetal tissue (minimum 2 mg) — is collected by your gynecologist during the clinical management of the miscarriage. The tissue must be placed immediately into sterile normal saline or 10% neutral-buffered formalin and kept refrigerated at 2–8°C. Freezing will destroy cellular integrity and invalidate the analysis. DNA Labs UAE can arrange temperature-controlled courier pickup from the hospital.
3. How do the results affect my future pregnancy planning?
A normal (negative) result suggests that the miscarriage was unlikely to have been caused by a major chromosomal error, prompting investigation of other potential etiologies. An abnormal (positive) result identifies the specific aneuploidy, allowing your gynecologist or geneticist to provide precise recurrence risk estimates and discuss prenatal testing options for subsequent pregnancies. All results are reviewed in the context of your full clinical and obstetric history during a dedicated genetic counseling session.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data derived from this test is encrypted, access-controlled, and processed solely for diagnostic purposes with explicit patient consent. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DHA Facility License No. 1143. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). For billing inquiries: +971 54 548 8731.
Clinical & Logistical Metadata
| Test Name | Chromosome Interphase Profiling (FISH) for Products of Conception |
| Price (AED) | 2,000 |
| Turnaround Time | 7 Working Days |
| Sample Type / Matrix | Placental or Fetal Tissue (Products of Conception) — Hospital Extraction Only |
| Methodology Used | Fluorescence In-Situ Hybridization (FISH) on Uncultured Interphase Nuclei |
| ICD-10-CM Code | O02.1 (Missed Abortion), O36.4 (Maternal Care for Intrauterine Death), N96 (Recurrent Pregnancy Loss) |
| LOINC Code | 53760-6 (Chromosomes 13,18,21,X,Y FISH.interphase) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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