Test Price
700 AEDโ Home Collection Available
BCL2 Gene Rearrangement, FISH Test in UAE | 700 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) Accredited Processing.
- Premium Logistics: Hospital Extraction Only โ Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Key Metrics
- Test Price: 700 AED
- Turnaround Time: 3โ4 business days
- Sample Type: Bone Marrow / Peripheral Blood (Hospital Extraction Only)
- Methodology: Fluorescence In-Situ Hybridization (FISH)
Test Overview & Methodology
BCL2 gene rearrangement testing by FISH is a molecular cytogenetic assay used to detect translocations involving the BCL2 gene, most commonly t(14;18), associated with follicular lymphoma and other B-cell malignancies. This test aids in diagnosis, risk stratification, and monitoring of minimal residual disease, delivering high precision with 99.9% sensitivity and a 3โ4 day turnaround.
| Feature | Our BCL2 FISH Test | Traditional Karyotyping |
|---|---|---|
| Methodology | FISH (Fluorescence In-Situ Hybridization) | Conventional G-banding karyotype |
| Sensitivity | >99% for BCL2 rearrangements | ~5โ10%; requires dividing cells |
| Turnaround Time | 3โ4 days | 2โ3 weeks |
| Sample Type | Bone Marrow / Peripheral Blood | Bone marrow (fresh sample required) |
| Price | 700 AED | Often >1200 AED |
Physician Insight & Safety Protocols
โUnderstanding your genetic markers can be daunting. I urge you to review your BCL2 FISH results with your oncologist or hematologist, as this test is one piece of a larger diagnostic puzzle. Clinical correlation with imaging, immunohistochemistry, and other biopsies is essential for a complete assessment.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Continuation
Do not discontinue prescribed medication without consulting your doctor. Always inform your healthcare provider of all medications and supplements before testing.
Safety Exclusion Criteria & Emergency Red Flags
Before Collection, Tell Your Phlebotomist If You Have:
- Uncontrolled bleeding disorder or easy bruising
- Active skin infection over the intended puncture site
- Pregnancy (for bone marrow biopsy without obstetric clearance)
- Allergy to local anesthetics
After Collection โ Seek Immediate ER Care If You Experience:
- Severe pain or increasing swelling at the collection site
- Prolonged bleeding beyond 30 minutes
- Fever over 38ยฐC within 48 hours
- Pus or foul-smelling discharge
Patient FAQ & Clinical Guidance
1. What is the BCL2 FISH test and why is it ordered?
BCL2 FISH testing uncovers gene rearrangements in follicular lymphoma for precise diagnosis and personalized therapy. It is ordered when lymphoma is suspected based on lymph node biopsy or unexplained cytopenias, and aids in differentiating follicular lymphoma from reactive conditions. The test detects the t(14;18) translocation causing BCL2 overexpression, a hallmark in many B-cell lymphomas.
2. How should I prepare for the bone marrow or blood collection?
No fasting required; tell your phlebotomist about any medications or bleeding conditions before the collection. For bone marrow aspiration, a mild sedative may be offered; arrange for a companion. Continue routine medications unless directed otherwise. Loose clothing and hydration are recommended.
3. What do the results mean?
Positive BCL2 FISH result signals follicular lymphoma, directing your oncologist to targeted therapy and prognosis. A positive result indicates the presence of BCL2 rearrangement, confirming or supporting a lymphoma diagnosis. It may guide eligibility for BCL2 inhibitors or clinical trials. Negative results do not wholly exclude lymphoma; clinical correlation is paramount.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is processed with strict confidentiality, encrypted storage, and controlled access. Clinical testing safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Our DHA facility license number 1143 ensures adherence to the highest standards of laboratory practice in Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | BCL2 Gene Rearrangement, FISH |
| Price (AED) | 700 |
| Turnaround Time | 3โ4 business days |
| Sample Type / Matrix | Bone Marrow / Peripheral Blood (Hospital Extraction Only) |
| Methodology Used | Fluorescence In-Situ Hybridization (FISH) |
| ICD-10-CM Code | C82.9 |
| LOINC Code | 48532-1 |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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