Test Price
2,800 AED✅ Home Collection Available
SLC6A14 Gene Cystic Fibrosis Modifier NGS Test in Dubai | 2800 AED
Executive Summary & Core Metrics
✔ Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited next-generation sequencing.
✔ Premium Logistics: Hospital-grade home collection with ISO-certified cold chain and VIP mobile phlebotomy, available daily 8 AM – 11 PM.
✔ Clinical Guidance: Post-test telephonic consultation with a consultant medical geneticist for result interpretation.
✔ Insurance & Billing: Direct billing verification via WhatsApp at +971 54 548 8731.
DHA Licensed Facility: DNA Labs UAE | License No. 1143 | Dubai Healthcare City
Test Overview & Methodology
The SLC6A14 gene NGS test identifies pathogenic variants in the SLC6A14 gene associated with cystic fibrosis modifier phenotypes and meconium ileus. This advanced sequencing assay provides comprehensive analysis of the entire coding region for precise diagnosis and carrier screening, targeting single nucleotide variants and small insertions or deletions with greater than 99.9% sensitivity.
Comparative Test Analysis
| Feature | SLC6A14 NGS Test (DNA Labs UAE) | Standard CFTR Mutation Panel |
|---|---|---|
| Methodology | Next-generation sequencing (full SLC6A14 gene) | Targeted mutation analysis (limited sites) |
| Diagnostic Precision | >99.9% sensitivity / 99.8% specificity | ~85% (misses rare and modifier variants) |
| Turnaround Time | 3–4 weeks | 2–4 weeks |
| Price | 2,800 AED | 1,500 – 2,200 AED |
* Turnaround begins after sample reception at the ISO-accredited laboratory. Home collection included.
Physician Insight & Safety Protocols
"As a consultant medical geneticist, I emphasize that SLC6A14 variant results must be interpreted alongside full CFTR analysis, clinical phenotype, and family history. A negative modifier result does not exclude cystic fibrosis. This test provides one piece of a complex diagnostic puzzle; please review your results with a genetic counselor or pulmonologist for integrated clinical management."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory – Do Not Alter Therapy Without Specialist Consultation
⚠ Important: Do not discontinue, adjust, or initiate any prescribed medication, enzyme therapy, or respiratory treatment based solely on genetic test results. All therapeutic decisions must be made by your treating physician or cystic fibrosis specialist after comprehensive clinical evaluation.
Exclusion Criteria & Urgent Clinical Indicators
- Exclusion Criteria: Active hemophilia or severe bleeding disorder (unless using FTA card sample obtained by trained professional); acute febrile illness at time of collection; inability to provide informed consent.
- Emergency Red Flags: If you or your child experience acute respiratory distress, severe abdominal pain with distension, or signs of meconium ileus in a newborn, seek immediate emergency medical care before proceeding with elective genetic testing.
- This test is not a substitute for comprehensive CFTR gene analysis. Clinical correlation with a cystic fibrosis specialist is mandatory for all results.
Patient FAQ & Clinical Guidance
1. What does the SLC6A14 gene test detect?
This test uses next-generation sequencing to identify pathogenic DNA variants in the SLC6A14 gene that act as cystic fibrosis modifier alleles. It scans the complete coding region for single nucleotide variants and small insertions or deletions that may influence disease severity and meconium ileus risk. Results provide a risk-modifier profile rather than a standalone diagnosis of cystic fibrosis.
2. How is the sample collected and can I use home phlebotomy?
A peripheral blood draw or FTA card finger-prick sample is collected by our DHA-licensed phlebotomist. We offer VIP mobile phlebotomy and temperature-controlled cold-chain home collection across the UAE daily from 8 AM to 11 PM. You may choose venous blood or a blood spot card based on your preference and clinical indication.
3. What does a positive result indicate for my health or my child's health?
A positive result signifies the presence of a pathogenic SLC6A14 variant linked to modified cystic fibrosis phenotype expression. It does not by itself diagnose cystic fibrosis; rather, it indicates a genetic factor that may modulate disease severity when combined with CFTR mutations. Positive findings guide specialist consultation, family cascade screening, and personalized monitoring plans with a pulmonologist or genetic counselor.
4. How long does it take to receive results?
The standard turnaround time is 3–4 weeks from sample reception at our ISO 9001:2015 accredited laboratory. Your referring physician will receive the full molecular report, which includes variant classification, clinical interpretation, and recommendations for follow-up.
5. Does insurance cover this genetic test?
Coverage varies by insurance provider and policy. We offer direct billing verification via WhatsApp at +971 54 548 8731. Please contact our billing team with your insurance details to confirm eligibility and any out-of-pocket costs before sample collection.
UAE Regulatory & Data Privacy Adherence
Data Protection & Confidentiality: All genetic data is processed and stored in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are encrypted and shared only with the ordering physician and patient upon explicit consent.
Clinical Safety & Consent: This test adheres to the standards outlined in Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring informed consent, patient autonomy, and clinical accountability throughout the testing pathway.
ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139 | DHA Facility License: 1143 | DNA Labs UAE
Clinical & Logistical Metadata
| Test Name | SLC6A14 Gene Cystic Fibrosis Modifier NGS Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood or FTA card blood spot |
| Methodology Used | Next-generation sequencing (NGS) – full gene coding region analysis |
| ICD-10-CM Code | E84.9, Z13.228 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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