Test Price
2,800 AEDโ Home Collection Available
Factor X Deficiency (F10 Gene) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
High-Reliability Molecular Diagnosis for Hereditary Bleeding Disorders
This next-generation sequencing (NGS) assay provides definitive molecular confirmation of pathogenic variants in the F10 gene, enabling precise diagnosis of hereditary factor X deficiency. The laboratory maintains ISO 9001:2015 certification and adheres to UAE federal health data regulations.
- Diagnostic Sensitivity >99% โ Full gene sequencing with CNV detection, validated against orthogonal methods.
- VIP Mobile Phlebotomy โ Temperature-controlled cold-chain home collection (8 AM โ 11 PM daily).
- Post-Test Genetic Counselling โ Telephonic consultation to discuss results and clinical implications.
- Direct Billing Support โ WhatsApp +971 54 548 8731 for insurance pre-approval.
Test Overview & Methodology
The F10 gene NGS test identifies single-nucleotide variants, small insertions/deletions, and copy-number alterations across the entire coding region and splice sites. This molecular approach resolves cases where functional clotting assays provide indeterminate results, particularly in mild or borderline deficiency states.
| Parameter | F10 Gene NGS Test | Functional Factor X Assay |
|---|---|---|
| Method | Next-Generation Sequencing (full gene, CNV analysis) | Clotting-time based activity measurement |
| Genetic Resolution | Single-nucleotide variants, insertions/deletions, copy-number changes | None (activity level only) |
| Diagnostic Sensitivity | >99% for known pathogenic variants | ~85% (may miss mild or heterozygous cases) |
| Turnaround Time | 3โ4 weeks | 1โ2 days |
| Price (AED) | 2,800 | ~500 |
Physician Insight & Safety Protocols
โThis NGS-based test provides the genetic blueprint of factor X deficiency, offering definitive molecular confirmation when clinical and family history raise suspicion. No genetic result should be interpreted in isolation; always correlate with coagulation assays and the patientโs bleeding phenotype. Never alter or discontinue prescribed factor replacement or anticoagulant therapy without direct consultation with the treating physician.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Anticoagulant and Factor Replacement Continuation
Continue all prescribed anticoagulants, antiplatelet agents, or factor X concentrate exactly as directed. Abrupt cessation of these medications may provoke thrombotic events or rebound hemorrhage. Genetic testing does not require any medication adjustment.
Exclusion Criteria & Emergency Indicators
- Inability to provide informed consent (minors require legal guardian permission per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Active febrile illness or hemodynamic instability at the time of specimen collection.
- Known allergy to antiseptic solutions or phlebotomy materials.
- Seek immediate emergency care if you develop sudden severe bleeding, expanding hematoma at the puncture site, or signs of anaphylaxis after collection.
Patient FAQ & Clinical Guidance
1. What does the F10 gene NGS test detect?
This test identifies disease-causing variants in the F10 gene responsible for hereditary factor X deficiency. It provides definitive molecular diagnosis, enables carrier detection within families, and guides long-term management planning for bleeding risk.
2. Do I need to stop blood-thinning medications before the test?
No. Continue all prescribed anticoagulants exactly as directed. Genetic testing does not require any medication changes, and stopping these drugs could provoke dangerous clot formation or hemorrhage.
3. How is the home blood collection performed?
A certified phlebotomist visits your home with a temperature-controlled cold-chain kit within your selected 8 AMโ11 PM slot. Stay well hydrated and have your Emirates ID and insurance card ready. The sample is transported directly to our ISO-certified laboratory under continuous temperature monitoring.
4. When will I receive my results and how are they delivered?
The full report is issued within 3โ4 weeks. Results are delivered via secure electronic medical record portal and followed by a telephonic genetic counselling session to explain findings, implications for family members, and recommended next steps.
UAE Regulatory & Data Privacy Adherence
Comprehensive Compliance Framework
- Data Protection: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Information Governance: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability & Consent: Operates under Federal Decree-Law No. 4 of 2016 on Medical Liability for all clinical procedures and patient consent protocols.
- Laboratory Certification: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | Factor X Deficiency (F10 Gene) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 weeks |
| Sample Type / Matrix | Peripheral whole blood โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM daily) |
| Methodology Used | Next-Generation Sequencing (NGS) with full F10 gene coverage, CNV detection, and orthogonal validation |
| ICD-10-CM Code | D68.2, Z14.8, Z84.1 |
| LOINC Code | 81306-3 |
| DHA Facility License & Laboratory Address | License #1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE • DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
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All reports reviewed by DHA-Certified physicians