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Test Price

2,800 AED

✅ Home Collection Available

F2 Gene (Prothrombin) Factor II Deficiency NGS Test in UAE | 2,800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Diagnostic Accuracy: 99.9% sensitivity achieved through ISO 9001:2015 certified processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
  • Post‑Test Guidance: Complimentary teleconsultation with a Consultant Medical Geneticist to explain results.
  • Insurance Verification: Direct coverage check via WhatsApp at +971545488731.

Test Overview & Methodology

The F2 Gene (Prothrombin) Factor II Deficiency NGS Test sequences the entire coding region and intronic boundaries of the F2 gene using Next‑Generation Sequencing. It identifies pathogenic variants causing congenital factor II deficiency (prothrombin deficiency) and the thrombophilic G20210A mutation. This comprehensive assay replaces limited PCR‑based hot‑spot analysis and enables earlier molecular diagnosis for at‑risk individuals in the UAE.

Feature DNA Labs UAE NGS Test Standard PCR‑Based Test
Precision Full gene coverage, all exonic & intronic boundaries Limited to G20210A hotspot only
Methodology NGS with dual‑strand error correction, verified by Sanger sequencing Real‑time PCR or restriction fragment length analysis
Turnaround Time 3 to 4 Weeks (DHA‑regulated) 5 to 7 Days (incomplete variant detection)

Physician Insight & Safety Protocols

“The F2 gene NGS test provides comprehensive mutation detection, but it must always be interpreted alongside a full coagulation workup, personal bleeding history, and family pedigree. No single result defines your health—trust the discussion with your haematologist and genetic counsellor.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

Important Medication Advisory

Do not discontinue prescribed anticoagulants, antiplatelet agents, or any other medications without consulting your treating physician. A genetic finding of factor II deficiency may require careful adjustment—never abrupt cessation.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Active, uncontrolled bleeding requiring immediate haemodynamic stabilisation; severe anaemia of unknown origin without prior haematological evaluation; inability to provide informed consent.
  • ER Red Flags: Sudden severe headache with neck stiffness, profuse bleeding from gums or injection sites, blood in urine or stool, or signs of intracranial haemorrhage – go to the nearest emergency department immediately.

Patient FAQ & Clinical Guidance

1. What is the F2 Gene Factor II deficiency test and who should consider it?

The F2 Gene Factor II deficiency test is a next‑generation sequencing assay that comprehensively screens the prothrombin gene for pathogenic mutations causing congenital bleeding disorder or thrombophilic risk. It is recommended for individuals with unexplained bleeding/bruising, prolonged clotting times, or a family history of factor II deficiency.

2. How should I prepare for the blood draw and what samples are accepted?

No fasting is required; simply stay hydrated and inform the phlebotomist of all medications, especially blood thinners. Accepted sample types: whole blood in EDTA tubes, extracted DNA, or a single drop of blood on an FTA card shipped at ambient temperature. VIP Mobile Phlebotomy is available daily from 8 AM to 11 PM across Dubai.

3. What do the results mean and how will I receive them?

Results clearly state whether a disease‑causing mutation was identified or not. A board‑certified genetic counsellor will explain the implications, including family risk. You will receive a secure, DHA‑compliant report via email and can schedule a free post‑test teleconsultation.

UAE Regulatory & Data Privacy Adherence

This test is performed under DHA Facility License No. 1143 and fully complies with:

  • Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring confidential handling of genetic and health data.
  • Federal Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields – governing digital health records and telemedicine.
  • Federal Decree‑Law No. 4 of 2016 on Medical Liability – guaranteeing patient safety and informed consent in clinical genetic testing.

ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139.

Clinical & Logistical Metadata

Test Name F2 Gene (Prothrombin) Factor II Deficiency NGS Test
Price (AED) 2,800 AED
Turnaround Time 3 to 4 Weeks
Sample Type / Matrix Peripheral Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card)
Methodology Used Next‑Generation Sequencing (NGS) with Sanger Verification
ICD‑10‑CM Code D68.2
LOINC Code 98124-0
DHA Facility License & Laboratory Address DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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