Test Price
5,200 AED✅ Home Collection Available
CLL NGS Panel (FISH, Karyotyping, IGHV & TP53 Mutation Analysis) in UAE | 5200 AED | 2026 DHA Guidelines
تحليل لوحة CLL الجينية الشاملة (FISH، النمط النووي، طفرات IGHV وTP53) في الإمارات | 5200 درهم | معتمد من هيئة الصحة بدبي
Executive Summary | الملخص التنفيذي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ضمان الدقة: حساسية تشخيصية تصل إلى 99.9% عبر معالجة معتمدة من ISO.
الخدمات اللوجستية المتميزة: خدمة سحب منزلي على مستوى المستشفى مع سلسلة تبريد معتمدة ISO وفريق تمريض متنقل VIP.
الإرشاد السريري: استشارة هاتفية بعد الاختبار لتفسير النتائج.
التأمين: التحقق المباشر من تغطية التأمين عبر واتساب على الرقم +971 54 548 8731.
Overview
The CLL NGS Panel is a definitive genomic stratification test for chronic lymphocytic leukemia, integrating karyotyping, FISH, PCR-based IGHV mutation analysis, and NGS for TP53. This single assay delivers the prognostic and predictive information required to personalise therapy according to 2026 DHA protocols.
| Feature | Our Test (CLL NGS Panel) | Standard FISH-Only Panel |
|---|---|---|
| Precision | 99.9% sensitivity for TP53 mutations (NGS depth >500x) | ~85% detection rate, low-level clones missed |
| Method | Karyotyping + FISH + PCR (IGHV) + NGS (TP53) | FISH probes only (13q, 11q, 17p, +12) |
| Turnaround Time | 3 weeks | 1–2 weeks |
Physician Insight & Safety Protocol
"CLL is a clinically heterogeneous malignancy where the mutational status of IGHV and TP53 defines both prognosis and therapeutic vulnerability. This integrated panel combines karyotyping, FISH, and high-sensitivity NGS to ensure no actionable mutation is overlooked, enabling your oncologist to craft a precisely tailored treatment plan. As with all laboratory tests, results must be interpreted within the full clinical context."
— Dr. PRABHAKAR REDDY, Consultant Hematologist (DHA License: 61713011)
⚠️ Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Safety Red Flags
- Pregnancy or suspected pregnancy (requires specialist referral).
- Active bleeding disorder or severe anaemia (Hb <7 g/dL) that contraindicates phlebotomy.
- Infection at the venipuncture site (cellulitis, abscess, or skin lesion).
- Inability to provide informed consent; for minors, an additional guardian consent per UAE CDS Law 2026.
- ER Red Flags After Blood Draw: Rapid onset of dizziness, fainting, chest pain, shortness of breath, or uncontrolled bleeding from the puncture site – seek emergency care immediately.
- FFPE block submission requires a previously performed biopsy; no additional risk beyond the original procedure.
Patient FAQ & Clinical Guidance
What is the CLL NGS Panel?
The CLL NGS Panel is a comprehensive genomic profiling that detects prognostic IGHV and TP53 mutations for personalised CLL management. It analyses peripheral blood or FFPE tissue using NGS and FISH to risk-stratify the leukemia and guide targeted therapy decisions.
لوحة CLL الجينية الشاملة هي اختبار جيني شامل يكشف عن طفرات IGHV وTP53 لتحديد مآل المرض واختيار العلاج المناسب وفق أحدث توصيات هيئة الصحة بدبي.
How is the sample collected?
A hospital-grade home collection service using cold-chain logistics ensures sample integrity for the CLL NGS Panel. A trained phlebotomist draws peripheral blood or collects the previously prepared FFPE block, which is then transported to our ISO-certified laboratory.
يتم سحب عينة الدم أو استلام الكتلة النسيجية (FFPE) بواسطة فريق تمريض متخصص في منزلك مع الحفاظ على سلسلة التبريد لضمان دقة النتائج.
What do mutations in IGHV and TP53 mean for my treatment?
Mutated IGHV indicates a more indolent CLL course, whereas unmutated IGHV and TP53 mutations predict aggressive disease that may require targeted therapies. Detection of TP53 mutations helps oncologists select inhibitors or clinical trials, significantly improving outcomes.
وجود طفرات في جين TP53 أو عدم وجود طفرات في IGHV يشير إلى مرض أكثر عدوانية ويوجه الطبيب نحو استخدام مثبطات محددة أو تجارب سريرية لتحسين النتائج.
Regulatory Compliance: This service adheres to Federal Decree-Law No. 41 of 2024 (Art. 87) on genetic testing confidentiality, UAE Child Protection (CDS) Law 2026 for minors, and UAE Personal Data Protection Law (PDPL). Laboratory processes are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) under MOHAP facility license 9834453.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians