CYBA Gene Chronic Granulomatous Disease (CGD, Cytochrome b‑Negative) Genetic Test in UAE | 2,800 AED

Executive Summary & Core Metrics

✅ Accuracy Guarantee

99.9% Diagnostic Sensitivity – ISO 9001:2015 certified laboratory processing with NGS full‑gene sequencing and CNV analysis.

🚑 Premium Logistics

VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM – 11 PM).

🩺 Clinical Guidance

Telephonic post‑test interpretation with a consultant medical geneticist; mandatory genetic counselling session included.

🏥 Insurance

Direct billing verification via WhatsApp. Send your insurance card to +971 54 548 8731.

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+971 54 548 8731

Test Overview & Methodology

The CYBA gene NGS test detects pathogenic mutations causing autosomal recessive chronic granulomatous disease (CGD) with cytochrome b‑negative phenotype. This advanced genetic analysis ensures precise diagnosis for recurrent infections and granuloma formation, guiding clinical management in UAE healthcare.

Feature	Our Test – NGS CYBA Gene	Closest Alternative – DHR Flow Cytometry
Precision	99.9% sensitivity – full gene sequencing + CNV detection	~95% for functional defect; cannot identify carrier status or specific mutation
Methodology	Next Generation Sequencing (NGS), Sanger confirmation	Dihydrorhodamine (DHR) flow cytometry
Turnaround Time	3–4 Weeks	2–3 Days
Price	2,800 AED	~1,200 AED
Clinical Utility	Definitive molecular diagnosis, family screening, prenatal testing	First‑line screening for CGD; requires genetic test for confirmation

Physician Insight & Safety Protocols

“As a Consultant Medical Geneticist, I emphasize that genetic testing for CYBA mutations must be interpreted alongside clinical findings and neutrophil oxidative burst assays. No single test defines CGD; a multidisciplinary approach ensures accurate diagnosis and appropriate prophylactic treatment.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License: 9294403

⚠️ Medication Warning

Do not discontinue prescribed medication without consulting your doctor. Genetic results never override urgent clinical judgment.

Exclusion Criteria & Emergency Red Flags

Active severe infection requiring hospitalisation — postpone testing until stable.
Home collection not recommended for infants <6 months or patients with difficult venous access.
Neonatal screening without family history of CGD is not validated; discuss with a geneticist.
ER Red Flags: Sudden shortness of breath, high fever with abscess formation, signs of septic shock — seek emergency care immediately.

Patient FAQ & Clinical Guidance

1. What exactly does this CYBA gene test detect?

This test detects pathogenic mutations in the CYBA gene, confirming autosomal recessive chronic granulomatous disease (CGD) with cytochrome b deficiency, enabling targeted prophylaxis.

2. How should I prepare for the test?

No special preparation is required; you can eat, drink, and take medications normally before blood collection.

3. When will I receive my results and genetic counselling?

Results are delivered within 3 to 4 weeks, and a mandatory post‑genetic counselling session will be scheduled to interpret findings for your family.

UAE Regulatory & Data Privacy Adherence

🔬 ISO 9001:2015 Certified Laboratory

Certificate: INT/EGQ/2509DA/3139 – All processing adheres to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent comply with Federal Decree‑Law No. 4 of 2016 on Medical Liability.

Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE.

Clinical & Logistical Metadata

Test Name	CYBA Gene Chronic Granulomatous Disease Genetic Test
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Whole Blood (Peripheral)
Methodology Used	Next Generation Sequencing (NGS) with Sanger Confirmation
ICD-10-CM Code	D70.1
LOINC Code	55353-1
DHA Facility License & Laboratory Address	DHA License: 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE