FISH Aneuploidy Screening (Chromosomes 13, 18, 21, X & Y) in UAE | 1300 AED | DHA Guidelines

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity through ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139), ensuring clinically actionable FISH signals for chromosomes 13, 18, 21, X and Y.
Sample Collection: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Clinical Guidance: Complimentary telephonic post‑test clinical interpretation by a DHA‑licensed physician, explaining your results within the UAE regulatory framework.
Insurance: Direct billing verification and pre‑approval assistance via WhatsApp +971 54 548 8731. We handle the paperwork while you focus on your health.

Test Overview & Methodology

This prenatal FISH test detects numerical abnormalities (aneuploidy) of chromosomes 13, 18, 21, X and Y using fluorescence in‑situ hybridization on uncultured amniocytes, chorionic villi, or cord blood. Results are available within 3‑4 days — markedly faster than conventional karyotyping — enabling early clinical decisions aligned with DHA maternal‑fetal care guidelines.

Feature	Our FISH Test	Conventional Karyotype (Alternative)
Method	Fluorescence In‑Situ Hybridization (FISH) – targets specific loci	Full chromosome culture and G‑banding
Speed (TAT)	3 – 4 days	10 – 14 days
Diagnostic Sensitivity	99.9% for five chromosome aneuploidies	>99% for all numerical/structural anomalies (broader scope)
Clinical Utility	Rapid reassurance or early intervention for common trisomies/sex aneuploidies	Comprehensive genome‑wide survey; longer reporting time

Physician Insight & Safety Protocols

“As a Consultant Medical Genetics, I stress that a positive FISH result must be confirmed by karyotype or microarray before any irreversible clinical decision. This test offers rapid, highly accurate initial information, but it does not substitute for comprehensive cytogenetic evaluation. Always correlate with ultrasound findings and maternal history.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication & Clinical Management

Do not discontinue or alter any prescribed medication without prior consultation with your treating physician. This genetic screening does not constitute medical advice regarding pregnancy management.

Exclusion Criteria & Emergency Red Flags

Maternal haemodynamic instability or active bleeding at the sample collection site.
Known allergy to local anaesthetics used during CVS/amniocentesis (hospital procedure adaptations apply).
Inability to obtain valid informed consent due to language barrier or acute distress.
ER Red Flags:
Severe abdominal pain, profuse vaginal bleeding, or rupture of membranes post‑procedure — proceed immediately to the nearest Emergency Department.
Fever >38.5°C or chills following invasive sampling.

Patient FAQ & Clinical Guidance

1. How quickly will I receive my FISH aneuploidy screening result in Dubai?

Your FISH analysis for chromosomes 13, 18, 21, X and Y is reported within 3 to 4 working days from sample receipt, thanks to our ISO‑certified cold‑chain transport and advanced fluorescence microscopy. This turnaround is significantly faster than conventional karyotyping, enabling rapid clinical decisions.

2. Is a doctor’s prescription mandatory for this prenatal genetic test in the UAE?

A valid DHA‑registered physician’s prescription is required for all individuals except pregnant women, patients undergoing surgery, or those planning international travel; we will verify eligibility during booking.

3. What sample types are accepted and where is the collection performed?

We accept amniotic fluid, chorionic villi, or cord blood. Sample collection is strictly conducted within an accredited hospital facility by qualified medical professionals. Mobile home phlebotomy is not available for these invasive specimens.

UAE Regulatory & Data Privacy Adherence

This test is performed under DHA Facility License No. 1143. All patient data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic information is encrypted, access-controlled, and never shared without explicit consent. Clinical safety and patient consent align with Federal Decree-Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name	FISH Aneuploidy Screening (Chromosomes 13, 18, 21, X & Y)
Price (AED)	1,300 AED
Turnaround Time	3 – 4 working days
Sample Type / Matrix	Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Methodology Used	Fluorescence In‑Situ Hybridization (FISH)
ICD-10-CM Code	Z13.7 (Encounter for screening for genetic and chromosomal anomalies)
LOINC Code	47244-3 (FISH analysis of 5 chromosomes in amniotic fluid)
DHA Facility License & Address	License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Corporate Lab: DNA Labs UAE