Test Price
2,800 AED✅ Home Collection Available
MPZ Gene CMT1B Genetic Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MPZ Gene CMT1B NGS Test is a definitive molecular diagnostic tool for Charcot-Marie-Tooth disease type 1B, detecting pathogenic variants in the myelin protein zero gene. This next‑generation sequencing assay provides unparalleled precision and is optimized for hereditary neuropathy evaluation under UAE genetic testing standards.
| Feature | Our Test (MPZ NGS) | Closest Alternative (CMT Panel) |
|---|---|---|
| Methodology | Hi‑depth Next‑Generation Sequencing (NGS) | Multiplex Ligation‑dependent Probe Amplification (MLPA) + Sanger |
| Analytical Sensitivity | >99.9% for SNVs, indels, CNVs (MPZ full coding region) | ~95% for known deletions; may miss rare point variants |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
Physician Insight & Safety Protocols
“Every CMT1B result must be interpreted in the full landscape of nerve conduction studies, family history, and clinical phenotype. A negative MPZ result does not exclude other hereditary neuropathies; genetic counselling remains the cornerstone of safe disclosure. I personally ensure each report is correlated with your neurologist’s findings.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Medication Guidance
⚠️ Important Medication Advisory
Do not discontinue any prescribed medication without consulting your treating physician. Genetic test results may inform future treatment strategy but never replace acute medical management or ongoing therapy adjustments.
Exclusion Criteria & Emergency Red Flags
Conditions Requiring Immediate Medical Attention
- Acute febrile illness or systemic infection within 48 hours of blood draw.
- Known coagulopathy or anticoagulant therapy not optimised – risk of haematoma.
- Recent blood transfusion (<2 weeks) – may cause sample chimerism.
- Inability to provide informed consent (patient must be legally capable or accompanied by legal guardian per Federal Decree-Law No. 4 of 2016 on Medical Liability for minors).
- Emergency red flags: Sudden severe weakness, respiratory distress, or rapid progression resembling Guillain-Barré syndrome – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What does a positive MPZ gene variant mean for my neuropathy diagnosis?
A positive MPZ variant confirms a molecular diagnosis of CMT1B, providing definitive aetiology for your neuropathy, guiding prognosis, and enabling accurate family risk assessment.
2. Is fasting or medication adjustment required before the blood collection?
No fasting or medication changes are required; continue all prescribed drugs and inform the phlebotomist of any anticoagulant use.
3. How long until I receive my results and who explains them?
Results are available in 3 to 4 weeks; a post-test teleconsultation with a clinical geneticist or neurologist is included for interpretation.
4. Can this test detect all types of Charcot-Marie-Tooth disease?
This test is specific to MPZ-related CMT1B. For broader evaluation of hereditary neuropathies, a comprehensive CMT gene panel may be recommended based on your clinical presentation and family history.
UAE Regulatory & Data Privacy Adherence
Compliance & Data Protection Framework
DNA Labs UAE operates under the full oversight of the Dubai Health Authority (DHA) and adheres to all applicable UAE federal laws governing genetic data and patient privacy:
- Data Privacy: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring your genetic information is processed lawfully, stored securely, and never shared without explicit consent.
- Health Data Governance: Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating the electronic handling, transmission, and storage of clinical records and genomic data.
- Medical Liability & Patient Consent: Federal Decree-Law No. 4 of 2016 on Medical Liability – governing informed consent procedures, clinical accountability, and patient safety standards.
Clinical & Logistical Metadata
| Test Name | MPZ Gene CMT1B Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection) |
| Methodology Used | Next-Generation Sequencing (NGS) – Hi‑depth, full coding region of MPZ |
| ICD-10-CM Code | G60.0 |
| LOINC Code | 82356-5 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians