Test Price
2,800 AED✅ Home Collection Available
SCN5A Gene (Atrial Fibrillation Type 10) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
🏥 Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Next‑Generation Sequencing.
📦 Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily 8 AM – 11 PM).
🩺 Clinical Guidance: Telephonic Post‑Test Genetic Counselling and Result Interpretation by a Consultant Medical Geneticist.
💳 Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SCN5A Gene (Atrial Fibrillation Type 10) Genetic Test employs Next‑Generation Sequencing (NGS) to comprehensively identify pathogenic and likely pathogenic variants in the SCN5A gene associated with familial atrial fibrillation type 10. This molecular analysis facilitates risk stratification for hereditary arrhythmia syndromes, guides clinical management decisions for cardiologists, and enables cascade screening for at‑risk family members. The assay achieves full coverage of all coding exons, flanking splice sites, and deep intronic regions implicated in cardiac ion channel dysfunction.
| Feature | DNA Labs UAE NGS Test | Standard Panel / Sanger Sequencing |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) – full gene coverage | Sanger sequencing or targeted hotspot panel |
| Coverage | Complete SCN5A coding region, all splice sites, deep intronic variants | Known mutation hotspots or limited exons |
| Turnaround Time | 21 to 28 Days | 4 to 6 Weeks |
| Cost | 2,800 AED | 2,500 – 3,500 AED (varies) |
Physician Insight & Safety Protocols
“As a DHA‑licensed Consultant Medical Geneticist, I emphasise that SCN5A genetic testing must be interpreted in the context of a complete cardiac evaluation including electrocardiogram, echocardiogram, and family history. A positive result indicates elevated genetic susceptibility to atrial fibrillation type 10, not a definitive diagnosis. All results require post‑test genetic counselling and correlation with clinical phenotype. Patients experiencing syncope, unexplained palpitations, or with a first‑degree relative who suffered sudden cardiac death should seek urgent cardiology review.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
⚠️ Critical Advisory – Do Not Alter Prescribed Therapy
Do not discontinue, adjust, or modify any prescribed antiarrhythmic medication, anticoagulant, or cardiac therapy without direct consultation with your treating cardiologist. Genetic test results complement clinical assessment but do not replace immediate medical management for symptomatic arrhythmia.
🔴 Exclusion Criteria & Emergency Red Flags
- Exclusion: Minors (under 18 years) cannot be tested without written informed consent from a parent or legal guardian as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Exclusion: Individuals unable to provide voluntary informed consent or those with uncorrected coagulopathy contraindicating venipuncture.
- Emergency Red Flag: Syncope accompanied by palpitations, sharp chest pain, or shortness of breath – requires immediate Emergency Department referral.
- Emergency Red Flag: New‑onset atrial fibrillation with hemodynamic compromise (hypotension, altered mental status, pulmonary congestion).
Patient FAQ & Clinical Guidance
1. What is the SCN5A gene test for atrial fibrillation type 10?
This targeted genetic test identifies heritable pathogenic variants in the SCN5A gene that cause familial atrial fibrillation type 10. The analysis uses next‑generation sequencing to scan the entire gene for disease‑causing mutations, enabling precise risk stratification for patients and their blood relatives. Results inform preventive cardiology strategies and guide clinical surveillance frequency.
2. How is the sample collected and what is the turnaround time?
A VIP mobile phlebotomist collects a peripheral blood sample from your home or office between 8 AM and 11 PM; results are ready within 21 to 28 calendar days. The specimen is transported via ISO‑certified temperature‑controlled cold‑chain logistics to our NGS laboratory. Genetic reports are delivered electronically through a secure patient portal and include a telephonic interpretation session with a Consultant Medical Geneticist.
3. Is this genetic test covered by health insurance in the UAE?
Insurance eligibility and direct billing are verified via WhatsApp at +971 54 548 8731; coverage varies by insurer and policy. Forward your insurance card to our billing team, and we will confirm pre‑approval requirements and any copayment obligations. Most major UAE health insurers provide partial or full coverage for genetic testing when ordered by a specialist cardiologist or geneticist.
4. What does a positive SCN5A result mean for my family members?
A positive result indicates a hereditary predisposition that may affect first‑degree relatives (parents, siblings, children). Cascade genetic screening is strongly recommended for all at‑risk family members. Each relative has a 50% chance of inheriting the pathogenic variant. Early identification enables proactive cardiac monitoring and lifestyle modifications to reduce arrhythmia risk.
5. Can this test detect all types of atrial fibrillation?
No. This test is specific to atrial fibrillation type 10 caused by SCN5A mutations, which accounts for a minority of familial AF cases. Other genetic loci and acquired factors contribute to the broader AF population. Your cardiologist will determine whether this targeted test or a broader arrhythmia gene panel is clinically appropriate based on your personal and family history.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and strictly complies with all UAE federal data protection and healthcare privacy regulations. All genetic data is processed and stored in full accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), ensuring that your genomic information is encrypted, access‑controlled, and never shared without explicit written consent. Additionally, our health information systems adhere to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, guaranteeing the confidentiality, integrity, and availability of electronic medical records. Clinical testing safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability, which mandates informed consent and establishes clear accountability standards for diagnostic procedures.
Clinical & Logistical Metadata
| Test Name | SCN5A Gene (Atrial Fibrillation Type 10) Genetic Test – Next‑Generation Sequencing |
| Price (AED) | 2,800 AED |
| Turnaround Time | 21 to 28 Calendar Days |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or Buccal Swab – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection |
| Methodology Used | Next‑Generation Sequencing (NGS) – Full Gene Coverage Including Splice Sites and Deep Intronic Regions |
| ICD-10-CM Code | I48.91, Z15.89 |
| LOINC Code | 96413-5 |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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